Ceramic Powder Made from Chicken Feces: Anti-Viral Effects Against Avian Influenza Viruses

Abstract

Ceramic powder prepared by sintering of chicken feces, when mixed with avian influenza viruses or an avian adenovirus, inactivated these organisms to below detection levels. When the ceramic powder was mixed with double-distilled water, the pH of the water rose to 10 but the aqueous phase did not show any antivirus activity. After 10 washings with water or five washings with 1M Tris-HCl (pH 8.0), the ceramic powder still retained antivirus activity. Antivirus activity was not affected by the presence of organic material (33% fetal calf serum). When chicks were fed food containing 5% ceramic powder, there was no difference in body weight between normal feeding and the ceramic-mixture feeding. The mode of action of the ceramic powder remains unknown, but it possibly works by adsorbing the virus. These results show that the ceramic powder has antiviral activities and is a potentially useful tool against avian influenza on poultry farms.

Inhibition of infectious bursal disease virus transmission using bioceramic derived from chicken feces

“…Previously, we demonstrated that if the virus liquid was not adsorbed completely in BCX, BCX could not inactivate the virus completely (Takehara et al, 2009). So the ratio of the amount of the powder and the volume of the virus liquid is important for inactivating the virus.…”

“…Inactivation was considered to be satisfied when RF was ≥3 (Alphin et al, 2009;Hasegawa et al, 2013;Lombardi et al, 2008;Takehara et al, 2009;Thammakarn et al, 2014).…”

“…The possibility of proposing BCX as feed additive was evaluated using 2 difference beginning ages of conventional chicks, according to protocol of Ministry of Agriculture, Forestry and Fisheries (MAFF) of Japan as described (Takehara et al, 2009). Two lots of conventional chicks, 6 and 8 days old were spent for testing, while 12 chicks of each lot were allotted into 2 cages equally.…”

“…Since a bioceramic powder (pH 10.6) was invented in Japan, its efficacy was first illustrated by the ceramic prepared from chicken feces to inactivate AI virus (Takehara et al, 2009). The present experiment investigates efficacy of a bioceramic powder (BCX) at pH 13, derived from chicken feces after sintering process, for applying during chick raising, aimed at stopping fecal-oral transmission, while using infectious bursal disease virus (IBDV) within the employed evaluation system.…”

Efficacy of scallop shell powders and slaked lime for inactivating avian influenza virus under harsh conditions

“…Inactivation was determined to be satisfactory when RF was greater than or equal to 3 [16,29,30]. The experiment was carried out three times, and the viral titers were averaged.…”