Cellulose membrane modified with LED209 as an antibacterial and anti-adhesion material

Zhou, Zongbao; Dong, Zixuan; Wang, Lei; Song, Rijian; Mei, Naibin; Chen, Tao; Luo, Lei; Ding, Qiang; Wang, Xiaoying; Tang, Shunqing

doi:10.1016/j.carbpol.2020.117138

Cited by 10 publications

(4 citation statements)

References 45 publications

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“…The combination of TPAD with LED209 could significantly enhance the bactericidal effect against MDR gram-negative bacteria such as Pseudoalteromonas and S. maltophilia , which opens an avenue to improve the antimicrobial efficiency of antimicrobial peptides ( Yu et al, 2020 ). Moreover, Zhou et al (2021) covalently modified cellulose membrane (CM) with LED209 via click reaction to produce an antibacterial material (LED209-CM). LED209-CM exhibited marked anti-adhesion ability to enterohemorrhagic E. coli , and significantly reduced the formation of bacterial biofilm.…”

Section: Novel Histidine Kinase-targeted Antimicrobial Agentsmentioning

confidence: 99%

Recent Advances in Histidine Kinase-Targeted Antimicrobial Agents

Chen

et al. 2022

Front. Chem.

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The prevalence of antimicrobial-resistant pathogens significantly limited the number of effective antibiotics available clinically, which urgently requires new drug targets to screen, design, and develop novel antibacterial drugs. Two-component system (TCS), which is comprised of a histidine kinase (HK) and a response regulator (RR), is a common mechanism whereby bacteria can sense a range of stimuli and make an appropriate adaptive response. HKs as the sensor part of the bacterial TCS can regulate various processes such as growth, vitality, antibiotic resistance, and virulence, and have been considered as a promising target for antibacterial drugs. In the current review, we highlighted the structural basis and functional importance of bacterial TCS especially HKs as a target in the discovery of new antimicrobials, and summarize the latest research progress of small-molecule HK-inhibitors as potential novel antimicrobial drugs reported in the past decade.

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Section: Novel Histidine Kinase-targeted Antimicrobial Agentsmentioning

confidence: 99%

Recent Advances in Histidine Kinase-Targeted Antimicrobial Agents

Chen

et al. 2022

Front. Chem.

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“…For example, Zhou et al attached LED209 onto cellulose via copper-catalyzed azide-alkyne cycloaddition (CuAAC) to obtain functionalized membrane with an antiadhesion ability. 18 Nouri-Felekori et al synthesized a novel citric acid-modified hydroxyethyl cellulose via click chemistry to prepare scaffolding materials for cartilage tissue engineering. 19 Nada et al functionalized cellulose acetate with 6-azido hexanoate group first, then applied CuAAC to produce nanofibers as wound dressing.…”

Section: Introductionmentioning

confidence: 99%

“…Functionalized cellulose and its derivatives via click chemistry has been reported and applied in the medical engineering field. For example, Zhou et al attached LED209 onto cellulose via copper‐catalyzed azide‐alkyne cycloaddition (CuAAC) to obtain functionalized membrane with an anti‐adhesion ability 18 . Nouri‐Felekori et al synthesized a novel citric acid‐modified hydroxyethyl cellulose via click chemistry to prepare scaffolding materials for cartilage tissue engineering 19 .…”

Section: Introductionmentioning

confidence: 99%

Fabrication of thermoresponsive micelles by functionalizing hydroxypropyl cellulose via azide‐alkyne click reaction

Wang,

Zhou

2023

Journal of Polymer Science

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In this work, we functionalized hydroxypropyl cellulose (HPC) by attaching tetraphenylethylene (TPE) via copper‐catalyzed azide‐alkyne cycloaddition (CuAAC). The obtained HPC‐TPE samples displayed water‐solubility, biocompatibility, fluorescence and thermoresponsive properties. The degree of substitution (DSTPE) of HPC‐TPE1 ~ 4 was determined to be 0.002, 0.006, 0.025, and 0.053, respectively. HPC‐TPE could self‐assemble into micelles in water with the hydrodynamic radius (Rh) ranging from 164 to 190 nm. Under different DSTPE, HPC‐TPE samples showed different lower critical solution temperature (LCST) behaviors in light transmittance, Rh and fluorescence. The critical transition temperatures in light transmittance for HPC‐TPE1 ~ 4 solutions were 55–49 °C during the heating process, and were 44–40 °C during the cooling process, respectively. Moreover, HPC‐TPE demonstrated a rapid and sensitive response to Fe3+ with ignoring interferences in the presence of other common metal ions, and could also be used to image 4T1 cells. Therefore, this work offered a general approach for the synthesis of functionalized polymers with promising applications in sensing and bioimaging.

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“…Various types of polymers have been used in the production of membranes for water separation applications, such as cellulose [20][21][22], cellulose derivatives [23][24][25], poly (ethersulfon) (PES) [26][27][28], poly (sulfone) (PSf) [29][30][31], and poly (vinyl chloride) (PVC) [32][33][34][35] as well as the batter. Interestingly, the rubber-based membrane had the potential to be utilized in wastewater treatment applications [36].…”

Section: Introductionmentioning

confidence: 99%

Natural Fiber-Reinforced Thermoplastic ENR/PVC Composites as Potential Membrane Technology in Industrial Wastewater Treatment: A Review

et al. 2022

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Membrane separation processes are prevalent in industrial wastewater treatment because they are more effective than conventional methods at addressing global water issues. Consequently, the ideal membranes with high mechanical strength, thermal characteristics, flux, permeability, porosity, and solute removal capacity must be prepared to aid in the separation process for wastewater treatment. Rubber-based membranes have shown the potential for high mechanical properties in water separation processes to date. In addition, the excellent sustainable practice of natural fibers has attracted great attention from industrial players and researchers for the exploitation of polymer composite membranes to improve the balance between the environment and social and economic concerns. The incorporation of natural fiber in thermoplastic elastomer (TPE) as filler and pore former agent enhances the mechanical properties, and high separation efficiency characteristics of membrane composites are discussed. Furthermore, recent advancements in the fabrication technique of porous membranes affected the membrane’s structure, and the performance of wastewater treatment applications is reviewed.

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Cellulose membrane modified with LED209 as an antibacterial and anti-adhesion material

Cited by 10 publications

References 45 publications

Recent Advances in Histidine Kinase-Targeted Antimicrobial Agents

Recent Advances in Histidine Kinase-Targeted Antimicrobial Agents

Fabrication of thermoresponsive micelles by functionalizing hydroxypropyl cellulose via azide‐alkyne click reaction

Natural Fiber-Reinforced Thermoplastic ENR/PVC Composites as Potential Membrane Technology in Industrial Wastewater Treatment: A Review

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