“…Plot of eradication rate versus T ϾMIC (assuming a MIC 95 of 0.015 g/ml) achieved over the duration of therapy, i.e., total T ϾMIC, for various penicillin (Pen VK) dose regimens (OE) (4,11,12,13,14,16,18,20,21,22,23,24,25,26,30,31,32,34,37,38,39,40,41,42,43,44,45,49,50) compared to those achieved by amoxicillin sprinkle (f, with 95% confidence interval shown as a bar) (based on average of both doses) and various amoxicillin dose regimens (᭜) (1,8,11,16,33,38) for the treatment of tonsillopharyngitis due to S. pyogenes. Model fit is based on penicillin VK data.…”