[Ce(l-Pro)₂]₂ (Oxa) as a heterogeneous recyclable catalyst: synthesis of pyrazoles under mild reaction conditions

Abstract

A highly efficient method for the synthesis of pyrazoles mediated by [Ce(l-Pro)2]2 (Oxa) as a heterogeneous catalyst.

Application and developing of iron‐doped multi‐walled carbon nanotubes (Fe/MWCNTs) as an efficient and reusable heterogeneous nanocatalyst in the synthesis of heterocyclic compounds

“…The route which uses 1,3‐diketones and aryl hydrazines is one of the most famous methods for the synthesis of substituted pyrazoles. Recently, the synthesis of pyrazoles have been reported by using the heteropoly acids, sulfamic acid, zeolite, SiO 2 ‐H 2 SO 4 , Baker's yeast/phosphate buffer/D‐glucose, and [Ce(L‐Pro) 2 ] 2 (Oxa) . However, these methods suffers from one or more drawbacks such as use of toxic, homogeneous and no recoverable catalysts.…”

“…Brown liquid; 88% yield (0.22 mg); 1 H NMR (250 MHz, CDCl 3 ): δ = 2.19 (s, 6H, 2CH 3 ), 5.90 (s, 1H, CH), 7.20–7.24 (m, 2H, ArH), 7.44–7.48 (m, 2H, ArH).…”

An Unexplored Lewis Acidic Catalytic System for Synthesis of Pyrazole and its Biaryls Derivatives with Antimicrobial Activities through Cycloaddition‐Iodination‐Suzuki Reaction

“…Once the C−X bond is formed in efficient manner, different cross coupling reactions can easily be performed through the C−X bond and it was well established by different known reactions . To synthesize the pyrazole core moiety, various Lewis acidic metal catalyzed methodologies such as [Ce(L‐Pro) 2 ] 2 (Oxa), Sc(OTf) 3 , Bismuth(III)trifluoroacetate, CeCl 3 .7H 2 O, nano‐TiO 2 , Zn[(L)proline] 2 , 12‐Tungstophosphoric acid, Layered Zirconium Sulfophenyl Phosphonate are well reported in literature but they are associated with various drawbacks such as high cost, complex catalyst preparation, harsh reaction conditions, elevated temperature etc. Therefore we tried to find out the milder way to synthesize pyrazole moiety with low cost, easily available Lewis acid metal catalyst.…”

C-S Cross-Coupling Reaction Using a Recyclable Palladium Prolinate Catalyst under Mild and Green Conditions

“…From this perspective, our research group has already described some protocols using hybrid catalysts in some reactions such as thio‐Michael, Kabachnik‐Fields and pyrazole synthesis in which these catalysts are reused. Aiming to describe a new, effective, green and low cost protocol for C−S cross‐coupling reaction, with a recyclable catalyst in large scale, including the synthesis of RN‐18, herein we present the palladium (II) bis‐ L ‐prolinate or Pd[( L )‐proline] 2 (Figure ) as a heterogeneous catalyst.…”