Causes of hospital admission of AIDS patients in southern Brazil, 2007 to 2012

Guerro, Anna Caroline; Andretta, Iliana Barbosa; Bello, Soraya Lamin; Trevisol, Daisson José; Schuelter-Trevisol, Fabiana

doi:10.1590/0037-8682-0235-2013

Cited by 6 publications

(16 citation statements)

References 8 publications

(9 reference statements)

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“…As was previously shown by us and by others [1,27,30] older age at the time of diagnosis was an independent risk factor for death. Not surprisingly, as was also reported by others, [23] mortality was higher among patients who were hospitalized 3 or more times during the years of the study (Fig. 3).…”

Section: Discussionsupporting

confidence: 88%

“…[10] As was reported by others, [7,13,16,17,23] the main causes for AIDS-defining illnesses hospitalizations were: Ly, PCP, TB, and recurrent pneumonia. Another quarter of hospitalizations were due to HIV-related diseases (mainly non-AIDS-related infections).…”

Section: Discussionmentioning

confidence: 70%

“…Studies from Barcelona, [16] United Kingdom, and Italy [17] reported similar percentage of hospitalizations due to AIDS-defining illnesses. Higher percentages of hospital admissions due to AIDS-defining illnesses were noted in south Brazil (40%) [23] and in a worldwide meta-analysis (46%). [18] This difference is probably the result of differences in the availability of HIV care in different countries.…”

Section: Discussionmentioning

confidence: 99%

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Hospitalizations of HIV patients in a major Israeli HIV/AIDS center during the years 2000 to 2012

et al. 2017

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To evaluate hospitalization rates and causes among human immunodeficiency virus (HIV) patients in the late highly active antiretroviral therapy (HAART) era. Data during the years 2000 to 2012 were obtained from hospital/clinical charts. Hospitalizations were defined as a ≥24 hours hospital admission. Obstetric admissions were excluded. Causes of hospitalizations were defined as acquired immune deficiency syndrome (AIDS)-defining illnesses, AIDS-related diseases (HAART adverse events, metabolic complications and non-AIDS-defining tumors/infections), and non-HIV-related diseases. Hospitalization rates are presented as admissions per 100 patient years. The number of HIV patients (58% males) in our center increased from 521 in 2000 to 1169 in 2012. 1676 hospital admissions (in 557 patients) were observed during the years of the study. The mean number of admissions per hospitalized patient was 3 ± 3.39. Hospitalization rates of HIV patients declined significantly (18.4/100 in 2000, 9/100 patient years in 2012; P = .0001), but it was higher than the rates reported in the Israeli general population (X8.76 in 2000, X6.04 in 2012). Furthermore, hospitalizations for AIDS-defining illness declined (from 46.9% to 16.1%) whereas non-HIV-related hospitalizations increased (from 31.3% to 60.1%). Lower cluster of differentiation 4 (CD4) cell counts and older age, at the time of HIV diagnosis, were associated with higher rates of admissions (especially for AIDS-defining illnesses) and mortality. Hospitalization rates of HIV patients, especially for AIDS-defining illness, continue to decline in the late HAART era despite the increasing age of the patients, though it is still higher than that of the general population. Low CD4 cell counts and older age, at the time of HIV diagnosis, are associated with readmissions and mortality.

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Section: Discussionsupporting

confidence: 88%

Section: Discussionmentioning

confidence: 70%

Section: Discussionmentioning

confidence: 99%

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Hospitalizations of HIV patients in a major Israeli HIV/AIDS center during the years 2000 to 2012

et al. 2017

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“…Regarding CD4+/CD8+ ratio, the proportion of individuals with values lower than 1 was higher among males (59% of cases). The same pattern was reported by Guerro et al 9 , who analyzed data from HIV patients admitted to hospital in Southern Brazil and found most to be male (67.4%). Between 2007 and 2015, among all cases of HIV reported by the Notifiable Diseases Information System (SINAN), Department of Ministry of Health of Brazil, there was a total of 61,904 cases in men and 31,331 cases in women 8 .…”

Section: The Latest Brazilian Acquired Immunodeficiency Syndrome/ Sexsupporting

confidence: 85%

“…According to the literature, parasitic and infectious diseases are the main causes of hospitalization among HIV-infected patients 9 . Neurotoxoplasmosis was the most prominent in this study, resulting in lower CD4 + /CD8 + ratios in both genders.…”

Section: The Latest Brazilian Acquired Immunodeficiency Syndrome/ Sexmentioning

confidence: 99%

Influence of comorbidities on CD4+/CD8+ proportion in HIV-positive patients in Blumenau, State of Santa Catarina: a retrospective study

Batista

Bogoni

Müller

et al. 2017

Rev. Soc. Bras. Med. Trop.

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Introduction:The objective was to identify comorbidities related to HIV-positive patients in Blumenau, State of Santa Catarina. Methods: A retrospective, descriptive observational design study which analyzed data from 424 patients assisted by the sexually transmitted disease/acquired immunodeficiency syndrome (STD/AIDS) Specialized Care Service (SCS). Results: Of 424 medical records analyzed, 388 patients presented CD4 + /CD8 + ratios lower than 1. The most prevalent comorbidities were smoking, depression, alcoholism, and herpes zoster infection, in males and females. Conclusions: The most relevant comorbidity in both genders was herpes zoster, an important marker of immunity in patients. The lowest mean was observed among patients with neurotoxoplasmosis.Keywords: HIV infection. Comorbidities. CD4 + /CD8 + ratio. Patients with HIV may have several comorbidities that could contribute to the reduction in the CD4 + /CD8 + ratio. It has been observed that long-term smoking decreases the number of CD4 + cells, and increases the number of CD8 + cells 7 .Our objective was to identify comorbidities related to HIVpositive patients treated at the sexually transmitted disease/ acquired immunodeficiency syndrome Specialized Care Of all 424 evaluated medical records that had data regarding CD4 + /CD8 + ratio, 388 patients presented values lower than 1. The analysis by sex showed 41% female and 59% male patients. The mean age of these patients was 35.54 (± 11.01) years, and the average age among HIV-positive men and women was 36.59 and 34.23 years, respectively. Of the 388 included patients, 243 (62.6%) were using specific antiretroviral drugs for HIV infection, highly active antiretroviral therapy (HAART), while 145 (37.4%) had never been on antiretroviral therapy (n = 113) or did not adhere to treatment (n = 32).

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HIV Related Admission and Associated Factors among Adult Patients Admitted to Medical Ward at Adama Hospital Medical College, Adama, Oromia, Ethiopia

Kassaye¹

2018

CMR

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Reports are indicating increased rate of HIV related admissions despite high coverage of anti-retroviral drug usage. The aim of this study was to assess the magnitude of HIV related admission and associated factors among adult patients admitted to Medical ward of Adama Hospital Medical College in Ethiopia. An institution based cross sectional study design was conducted by using the formula to estimate a single population proportion (P) of 65% taken from HIV case hospital bed occupancy in Addis Ababa hospitals to select a total of 549 patients. Data were collected by an interviewer administered pre tested structured questionnaires. The 95% confidence intervals with p-value of less than 0.05 were considered statistically significant. Analysis was performed by using Statistical package for the social sciences (SPSS v 21) software program. A total of 538(97.9%) patients were involved in a study out of which, 120(22.3%) of them were HIV cases with various clinical manifestations. Toxoplasmosis was the commonest 32(26.7%) opportunistic infection. Patients who had divorced, widowed or separated were 2.6 (

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Causes of hospital admission of AIDS patients in southern Brazil, 2007 to 2012

Cited by 6 publications

References 8 publications

Hospitalizations of HIV patients in a major Israeli HIV/AIDS center during the years 2000 to 2012

Hospitalizations of HIV patients in a major Israeli HIV/AIDS center during the years 2000 to 2012

Influence of comorbidities on CD4+/CD8+ proportion in HIV-positive patients in Blumenau, State of Santa Catarina: a retrospective study

HIV Related Admission and Associated Factors among Adult Patients Admitted to Medical Ward at Adama Hospital Medical College, Adama, Oromia, Ethiopia

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