Catheter-based infrared light scanner as a tool to assess conduit quality in coronary artery bypass surgery

Abstract

OCT imaging provides an accurate, real-time, and reproducible means for assessing saphenous vein graft and radial artery graft bypass conduits. As a quality assurance tool, this technology might afford a more objective basis for conduit selection.

The Role of Preexisting Pathology in the Development of Neointimal Hyperplasia in Coronary Artery Bypass Grafts

“…Four separate 5 thick sections were cut from each graft. Intimal and media thickness was measured in hematoxylin and eosin stained sections using image analysis software (Bioquant Nova Prime, Nashville, TN) and the intima-media ratio was calculated for each graft [13].…”

Optical Coherence Tomography Imaging as a Quality Assurance Tool for Evaluating Endoscopic Harvest of the Radial Artery

“…The change in mean luminal volume measured from the in situ and ex vivo OCT scans, a measure of RA spasm, was compared between groups using a t test. In preliminary data using discarded RA segments, we found that ERAH was associated with a fivefold increase in minor intimal injury vs open RA harvest [10]. Therefore, 25 RAs per group were expected to provide an 80% power to detect a fourfold difference in intimal injury between groups at p = 0.05.…”

“…The OCT images were analyzed by 2 technicians blinded to group assignment, with harvesting injury categorized as minor when intimal disruption was restricted to the ostia of branch points and severe when the luminal surface was involved [10]. Luminal volume of the RA was calculated from OCT data using automated imaging processing software.…”

“…Our group has shown that catheter-based optical coherence tomography (OCT) provides images of the conduit at near histologic resolution, which is a far better method for detecting focal pathology within bypass conduits intraoperatively compared with histology [10]. This study used a clinical and cadaver model to evaluate OCT as a tool for intraoperative feedback on the quality of RAs procured using ERAH vs open techniques.…”

Clinical optical diagnostics – Status and perspectives

“…The radial scanner was developed for coronary artery characterisation [87]. The probe produces cross-sectional images of the vessel wall while it rotates (see Fig.…”