Carriers based on poly-3-hydroxyalkanoates containing nanomagnetite to trigger hormone release

Castro, Mayara de Freitas e; Mendonça, Thatiane Teixeira; Silva, Luiziana Ferreira da; Gomez, José Gregório Cabrera; Rodríguez, Rubén Jesus Sánchez

doi:10.1016/j.ijbiomac.2020.10.203

Cited by 5 publications

(1 citation statement)

References 62 publications

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“…Furthermore, the incorporation of compounds can also serve to modulate the release of the drug by the carrier, as well as the incorporation of superparamagnetic nanoparticles. A carrier with a thermal responsive property regulated by magnetic oscillation was demonstrated to be a promising candidate for veterinary application when PHA copolymers were combined with nanomagnetite to achieve controlled progesterone release [69]. G.H.…”

Section: Drug Carriersmentioning

confidence: 99%

Recent Biotechnological Applications of Polyhydroxyalkanoates (PHA) in the Biomedical Sector—A Review

Diniz,

Mourão,

Xavier

et al. 2023

Polymers

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Petroleum-derived plastics are materials of great importance for the contemporary lifestyle, and are widely used commercially because they are low cost, resistant, malleable, and weightless, in addition to their hydrophobic character. However, some factors that confer the qualities of these materials also cause problems, mainly environmental, associated with their use. The COVID-19 pandemic aggravated these impacts due to the high demand for personal protective equipment and the packaging sector. In this scenario, bioplastics are environmentally positive alternatives to these plastics due to their applicability in several areas ranging from packaging, to biomedicine, to agriculture. Polyhydroxyalkanoates (PHAs) are biodegradable biopolymers usually produced by microorganisms as an energy reserve. Their structural variability provides a wide range of applications, making them a viable option to replace polluting materials. PHAs can be applied in various biotechnology sectors, such as producing drug carriers and scaffolds for tissue engineering. This review aimed to survey works published in the last five years on the study and biotechnological application of PHAs in the biomedical sector, exploring the versatility and advantages of their use and helping to understand how to enhance their application.

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Section: Drug Carriersmentioning

confidence: 99%