Carp (Cyprinus carpio L.) innate immune factors are present before hatching

Ontogeny and tissue-specific expression of innate immune related genes in rohu, Labeo rohita (Hamilton)

“…The transferrin mRNA was detected only in liver of rohu juveniles. In carps, the liver starts developing before hatching and it is extremely small and immature at this time [35] and this might be the reason for the presence of transferrin in rohu from 6 h post-fertilization onwards. Similarly, transferrin mRNA alleles were also detected in liver in very high amount and to a much lesser extent in head kidney, thymus and spleen of common carp [12].…”

Short and long peptidoglycan recognition proteins (PGRPs) in zebrafish, with findings of multiple PGRP homologs in teleost fish

“…The present study also showed that all these three genes are maternally derived, especially for zfPGRP-L that is expressed at a high level in unfertilized eggs. Maternal mRNA of innate immune factors including complement factor 3 (C3), ␣ 2 -macroglobulin (␣ 2 M), serum amyloid A (SAA), complement factor 1 r/s-mannose binding lectin associated serine proteaselike molecule (C1/MASP2) and Ig protein, were present in unfertilized eggs and considered to play an important role in defending the egg (Huttenhuis et al, 2006). The high level expression of zfPGRP-L and zfPGRP-SC in fish egg and embryo development stages indicated that both of them might play implicated role in addition to innate immunity, which was supported by the unreported results that gene silencing of zebrafish PGRPs involves in the Wnt, BMP, toll-like receptor and other signal pathways (unreported observation).…”

Effects of dietary β-glucan on maternal immunity and fry quality of rainbow trout (Oncorhynchus mykiss)

“…Both innate and adaptive types of immune factors are transferred from mother to offspring in fishes. Immunoglobulin, as the most important maternal immune factor in vertebrates (Picchietti et al, 2006), and other innate immune factors such as the complement components (Huttenhuis et al, 2006), lectins (Hasan et al, 2009), lysozymes (Magnadóttir et al, 2005), and antimicrobial peptides (Seppola et al, 2009) have been found to be transferred maternally by protein or mRNA in several fish species.…”