“…Individuals who typically react with increases in TPR that are not offset by decreases in CO may be at risk due to atherosclerotic changes arising from repeated or prolonged periods of increased vascular resistance (Gregg et al, 2002 There is a growing body of evidence to suggest that blunted, rather than exaggerated, physiological reactivity is associated with a range of health outcomes such as depression and obesity (Carroll et al, 2007;York et al, 2007;Carroll et al, 2008). Studies have shown that those who respond best to a vaccination challenge show greater cardiovascular and cortisol reactions to stress (e.g., Phillips et al, 2009), while young adolescents who spent a greater proportion of their lives in poverty show muted CVR to acute stress (Evans and Kim, 2007).…”