Carcinoma of stomach: evaluation of individual and combined diagnostic accuracy of radiology, cytology, and gastrophotography.

Blendis, Laurence M.; Beilby, J. O. W.; Wilson, Joe; Coles, Melissa

doi:10.1136/bmj.1.5541.656

Cited by 15 publications

(4 citation statements)

References 15 publications

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“…Besides, patients with chronic hepatitis or liver cirrhosis also have higher level of AFP. It was estimated that 85% patients with HCC were followed by chronic hepatitis [ 30 ]. Missed diagnostic can happen easily under these situations.…”

Section: Discussionmentioning

confidence: 99%

Clinical utility of decarboxylation prothrombin combined with α-fetoprotein for diagnosing primary hepatocellular carcinoma

et al. 2018

Bioscience Reports

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We conducted a comprehensive analysis to evaluate clinical utility of decarboxylation prothrombin combined with α-fetoprotein (AFP) for diagnosing primary hepatocellular carcinoma (HCC). Systematical searches were performed in PubMed, Web of Science, China National Knowledge Internet, and Wangfang databases. The bivariate random-effect model was used to calculate the pooled sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood, diagnostic odds ratio (DOR), and summary area under the curve (AUC). Fourteen studies were included in the meta-analysis. For decarboxylation prothrombin, the overall pooled parameters are as follows: sensitivity: 79% (95% confidence interval (CI): 74–84%), specificity: 91% (95%CI: 87–93%), PLR: 8.42 (95%CI: 5.79–12.23), negative likelihood ratio (NLR): 0.23 (95%CI: 0.17–0.30), DOR: 37.09 (95%CI: 21.37–64.36), summary AUC: 0.92 (95%CI: 0.89–0.94); for combined diagnostic, the overall pooled parameters were as follows: sensitivity: 91% (95%CI: 85–95%), specificity: 83% (95%CI: 74–89%), PLR: 5.26 (95%CI: 3.53–7.83), NLR: 0.11 (95%CI: 0.07–0.18), DOR: 47.14 (95%CI: 30.09–73.85), summary AUC: 0.94 (95%CI: 0.91–0.95). The serum decarboxylation prothrombin showed a relatively higher diagnostic specificity for primary HCC and decarboxylation prothrombin combined with AFP exhibited can improve sensitivity for HCC than any of the biomarkers alone.

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Section: Discussionmentioning

confidence: 99%

Clinical utility of decarboxylation prothrombin combined with α-fetoprotein for diagnosing primary hepatocellular carcinoma

et al. 2018

Bioscience Reports

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“…If a lesion shows features suggestive of malignancy, exfoliative cytology may be performed with a separate tube at the same time as fibregastroscopy (Kidokoro, 1966;Blendis, Beilby, Wilson, Cole, and Hadley, 1967). The tube for gastric lavage can be passed alongside the fibrescope, and some measure of guidance is possible so that a jet of saline can be directed at the lesion.…”

Section: Discussionmentioning

confidence: 99%

“…Patients with carcinoma seldom required gastroscopy as diagnosis was obvious as seen by barium meal but fibregastroscopy prevented unnecessary laparotomy where the radiologist had raised doubts about possible malignancy, as may happen with large, irregular gastric folds. Direct vision of suspicious areas has been more satisfactory than the experience of Blendis et al (1967) using the blind gastrocamera without the fibrescope. Also, unsatisfactory examinations after the tube has been introduced into the stomach have been rare.…”

Section: Discussionmentioning

confidence: 99%

Gastroscopy and gastric photography with the Olympus GTF-A

Cockel¹,

Hawkins²

1970

Gut

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“…Microscopically, nearly all gastric cancers were of the adenocarcinoma type varying only in the degree of differentation. Pathological staging of carcinoma stomach depends on essential part of the operative strategy and histopathological reports from resected specimen 25…”

Section: Histopathologymentioning

confidence: 99%

A Clinico-pathological Correlation of Carcinoma Stomach and ABO Blood Group

2021

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Introduction: Stomach cancer related to higher rate for blood group A over other ABO types, a prospective assessment of relation between blood group and carcinoma stomach was performed with a view to state the role of ABO blood group in the development of gastric cancer with relationship of clinico-pathological variation. This study sought to investigate the relationship between ABO blood groups and the risk of gastric cancer as well as clinical pathological parameters. Materials and Methods: A Prospective random observational study carried between October 2005 to September 2006 in Dhaka Medical College Hospital, Department of Surgery & Radiotherapy. Maximum patients admitted in the surgery units with diagnosed case of carcinoma stomach were taken as sample or study population & rest attended in radiotherapy department in DMCH. Results: Among the 70 cases the mean age is 44.3(18-65) (M/F=4:1) years. All the information and data taken from Hospital records and patients themselves or first degree relatives. Results Blood group B-42.85%, A-34.28%, O- 15.71% only 11.42% gave positive family history. Histopathological report show's Adenocarcinoma 95% and among them blood group B 40% and A 31.42%. The differentiation of carcinoma stomach are categorized as Grade-I well differentiated, 37.14% cases moderately differentiated 15.71% and poorly differentiated 45.71%. Among them blood group B is more in case of poorly differentiated carcinoma 25.71%, blood group A is more in well differentiated carcinoma 17.14%. Conclusion: Blood group 'A' has an established relationship with carcinoma stomach. In this study it is found that blood group 'B' is more associated with carcinoma stomach and with poorly differentiated adenocarcinoma. Medicine Today 2021 Vol.33(1): 27-33

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Carcinoma of stomach: evaluation of individual and combined diagnostic accuracy of radiology, cytology, and gastrophotography.

Cited by 15 publications

References 15 publications

Clinical utility of decarboxylation prothrombin combined with α-fetoprotein for diagnosing primary hepatocellular carcinoma

Clinical utility of decarboxylation prothrombin combined with α-fetoprotein for diagnosing primary hepatocellular carcinoma

Gastroscopy and gastric photography with the Olympus GTF-A

A Clinico-pathological Correlation of Carcinoma Stomach and ABO Blood Group

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