Carbon nanotube–mediated antibody-free suspension array for determination of typical endocrine-disrupting chemicals

Suspension array platform based on aptamer for high-throughput detection of five environmental hormones

“…The SEM can enlarge targets tens of thousand times and intuitively observe the structural changes on the surface of substance. The zeta potential informs the degree of bonding between chemical bonds through the change of potential [37]. We employ SEM to scan the surface of MBs (Fig.…”

Application of aptamer functionalized nanomaterials in targeting therapeutics of typical tumors

“…However, the intermolecular interaction, site, and mode of action are the key factors in constructing multifunctional nanomaterials. Nan Liu’s team explored the binding characteristics of aptamers and compounds ( Zhang et al, 2019 ), the interaction between carbon nanotubes and aptamers ( Liu et al, 2020a ), and established a new evaluation method for molecular beacon binding system ( Jia et al, 2017 ), which laid a certain foundation in the research of aptamer-functionalized nanomaterials. The system based on AFNs composites not only has the dual characteristics of aptamer and nanomaterials, but also has new characteristics such as high affinity, strong degradation, and high cell uptake between functionalized nano-materials and targets.…”