Carbon isotopes in vanillin and the detection of falsified natural vanillin

Abstract

A method has been developed for quantitative removal of the methyl group carbon from vanillin and determination of its isotopic composition. The method is of value for the detection of synthetic vanillins whose isotopic compositions have been adjusted by the addition of [methyZ-13C]vanillin to resemble natural vanillins.

Forensic applications of isotope ratio mass spectrometry—A review

“…Numerous publications have addressed research in this field, and cover the analysis of substances such as flavours, fragrances, wine, fruit juice, honey, and vegetable oils [6,11,23,[52][53][54][55][56][57][58][59][60][61][62][63][64].…”

Recovery of vanillin from Kraft lignin oxidation by ion-exchange with neutralization

“…Nowadays, approximately 50% of the worldwide production of synthetic vanillin is used by the chemical and pharmaceutical industries for the production of herbicides, antifoaming agents, household products or drugs [1,6,7]. The antioxidant and antimicrobial properties are applied in use of vanillin as a food preservative [2,8,9]. It exhibits the activity against both Gram-positive and Gram-negative food-spoilage bacteria and also shows antimutagenic effect, for instance, as a suppressor of chromosomal damages [10][11][12][13].…”

Obtenção de vanilina: oportunidade biotecnológica

“…Nesta análise é feito um perfil de isótopos usando um espectro de massa ( 13 C EMPI) ou o método de ressonância magné-tica nuclear ( 2 H-RMN) onde é possível destinguir a origem natural ou sintética da vanilina, já que a percentagem de 13 C na vanilina de origem da orquídea Vanilla planifolia difere da sintética [7][8][9][10][11][12][13] . Os métodos de análise usados para controle de qualidade incluem cinzas, acidez total, espectroscopia UV, cromatografia de camada delgada e em papel [14][15][16] , cromatografia gasosa e líquida de alta eficiência 17,18 .…”