Caracterización de los episodios de neutropenia febril en niños con leucemia mieloide aguda y leucemia linfoblástica aguda

Abstract

period of time and had a worse clinical outcome, as evidenced by > hemodynamic instability, > sepsis, CRP > 90 mg/L for a longer time, more days of hospitalization, > frequency of hospitalization in ICU, > bacteremia, mainly by Streptococcus viridans group, > change of antimicrobial treatment, > use of antifungal therapy. Conclusions: This study demonstrates that FN episodes in children with ALML further evolve unfavorably, compared with episodes of FN in children with ALL. FN episodes in children with ALML require a more aggressive diagnostic and therapeutic approach, related to its severity.]]>

Contributions of a regional approach to document hematologic disease in Mexico: a 10-year experience in an open population

“…Median age was 10 years (0-79), five years younger than in the US [10]. In our children's group, median age was 6 years (0-17), similar to other LMICs, with results between 5 and 6.4 years [12,13]. Recently, we defined survival rates for adult ALL patients [14], for children [15] and adolescents [16] as well as relapse and its outcomes in the pediatric group [17] over a decade.…”

Caracterización microbiológica y de susceptibilidad antimicrobiana de las infecciones asociadas a neutropenia febril en pacientes hemato-oncológicos pediátricos

“…Cercano a lo reportado en los mismos centros entre 2004 y 2009, donde la frecuencia de aislamiento de los CGP fue predominante (56%), siendo los agentes más frecuentes SCN, E. coli, S. viridans y S. aureus; con resistencia a Oxacilina en un 77% de SCN y 14% de S. aureus 27 . Resultados similares fueron descritos por Cortez en 2008 y Ducasse en el 2014 28,29 . Maldonado propone que esta similitud en las resistencias a pesar del paso de los años, corresponde al conocimiento riguroso de la epidemiología local que lleva al uso racional de antibióticos; en contraste con el incremento de las resistencias observado en otros países 26 .…”

Bloodstream infection in pediatric patients with febrile neutropenia induced by chemotherapy

“…The predominant infectious foci are the lower respiratory tract, urinary tract and gastrointestinal tract. 3 , 4 , 5 , 6 , 7 , 8 Infections confirmed by clinical or microbiological tests account for less than half of all the cases of FN and most children present no symptoms during treatment. 9 …”