Caracterização dos distúrbios cognitivos na Doença de Parkinson

Galhardo, Mônica Maria de Azevedo Mello Carvalho; Amaral, Ana Karênina de Freitas Jordão do; Vieira, Ana Cláudia de Carvalho

doi:10.1590/s1516-18462009000600015

Cited by 22 publications

(15 citation statements)

References 7 publications

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“… 38 However, studies show that PD patients exhibit no decline in recognition memory. 7 , 39 The impaired recognition performance in the PDDS group, when compared to the PD group, suggests an influence of the association between depressive symptoms and MCI, given the same task showed a decline when the performance between the CGDS and PD groups, and the CGDS and CG groups were compared. Therefore, PDDS and CGDS had impaired recognition performance compared to the groups without depressive symptoms.…”

Section: Discussionmentioning

confidence: 98%

Symptoms of depression in patients with mild cognitive impairment in Parkinson's disease

Malak

Vasconcellos

Pereira

et al. 2017

Dement. neuropsychol.

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ObjectiveTo investigate the most frequent depressive symptoms and their association with cognition in Parkinson's disease (PD) patients with mild cognitive impairment (MCI).Methods48 patients with PD and 44 controls (CG), aged between 50 and 80 years and with at least 4 years of formal education, all with MCI and none diagnosed with depression, were assessed. Patients and controls were matched for age, education, and Mini-Mental State Examination (MMSE) score. Participants underwent clinical evaluation with a neurologist followed by neuropsychological assessment employing the instruments: MMSE, Clock Drawing Test, Verbal Fluency Test (semantic and phonemic), Figures Memory Test (FMT), Stroop Test, Trail Making Test, Digit Span (WAIS III), Rey Auditory Verbal Learning Test (RAVLT), Hooper Visual Organization Test, and Beck Depression Inventory (BDI).ResultsThe most frequent depressive symptoms in the PD group were: difficulty working, fatigue and sleep disorders (the latter also being present in CG). BDI score correlated negatively with learning and recognition memory in both groups. Episodic memory, evaluated by the FMT and RAVLT tests, was the cognitive function showing greatest impairment.ConclusionSome of the depressive symptoms observed in PD patients with MCI seem to be attributable to complications of PD, while others are common to both PD and MCI, making differential diagnoses complex but crucial.

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Section: Discussionmentioning

confidence: 98%

Symptoms of depression in patients with mild cognitive impairment in Parkinson's disease

Malak

Vasconcellos

Pereira

et al. 2017

Dement. neuropsychol.

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“…Other changes characteristic of the disease are hypomimia, decreased blink rate and hypophonia, decreased arm swing and the tendency for the foot of the more affected side to drag, micrographic changes, deficit in saliva swallowing and the presence of sialorrhoea (15). Pain often results from a lack of mobility in the affected limbs, with shoulder pain being a common complaint (16).…”

Section: Methodsmentioning

confidence: 99%

Evaluation of functional changes in the evolutionary stages of Parkinson's disease: a case series

Nascimento

Albuquerque

2015

Fisioter. mov.

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Introduction : Parkinson's disease is one of the fastest growing neurological disorders in the world and is considered to be predominantly a motor disorder, classified as neurodegenerative, chronic and extrapyramidal, characterized by tremors, muscular rigidity, postural balance deficit and bradykinesia. Objective : To analyze the functional changes presented by Parkinson's disease patients in the different evolutionary stages of the disease. Methods : The sample included 30 patients of both genders, aged between 51 and 75 years, with clinical diagnoses of Parkinson's disease in different evolutionary stages, undergoing physiotherapy in the Pernambuco Parkinson Association. The patients were evaluated through the Hoehn and Yahr Staging Scale and the Unified Parkinson's Disease Rating Scale (UPDRS). Results : The results highlighted an increase in the presence and severity of the changes presented by the Parkinson's disease patients, according to the evolution of the stages of the disease, especially considering aspects relating to motor activity and activities of daily living, including changes related to speech, swallowing, the ability to get dressed, personal hygiene, turning in bed and arising from a chair, occurrence of falls, posture, gait, postural stability and the presence of bradykinesia/hypokinesia. Conclusion : It is believed that the classification of the evolutionary stage of patients through the Hoehn and Yahr Scale and the registration of functional change through the UPDRS are useful for the development of the physiotherapy treatment plan.

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“…As FE atingiram seu ápice na espécie humana e resultam diretamente da atividade desempenhada pelo córtex pré-frontal (CPF), além de outras áreas corticais e subcorticais do cérebro relacionadas aquele (Galhardo, Amaral, & Vieira, 2009). As FE são um conjunto abrangente de habilidades que permitem que um indivíduo direcione seu funcionamento cognitivo, comportamental e emocional a metas, relacionando-se com a habilidade de responder de forma adaptativa a novas situações.…”

Section: Deterioro Ejecutivo En Fase Leve a Severa De La Enfermedad Dunclassified

Comprometimento Executivo nas Fases Leve à Grave da Doença de Parkinson

Macuglia

Rieder

Trentini

et al. 2015

Psico

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A Doença de Parkinson (DP) é uma desordem neurodegenerativa caracterizada por disfunções motoras, mas também marcada por alterações executivas. O presente estudo investigou funções executivas em indivíduos saudáveis e pacientes parkinsonianos com grau variável de comprometimento. Foram avaliados 30 controles saudáveis e 40 pacientes com DP utilizando os instrumentos Hoehn e Yahr, WAIS-III, MEEM, MoCA, Stroop e BADS. Pacientes com DP evidenciaram significativo prejuízo nas funções executivas, quando comparados às pessoas do grupo controle. Houve um percentual de 72,5% de pacientes com disfunção executiva (DE), distribuídos em todos os estágios da DP, sendo que mulheres, indivíduos com menor escolaridade e aqueles com idade avançada apresentaram disfunções mais severas do que os demais pacientes. Portanto, o número de pacientes com alterações executivas foi significativo, não estando estas relacionadas ao agravamento da doença. No entanto, algumas variáveis dos indivíduos da amostra se mostraram protetivas para o agravamento das disfunções.

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Caracterização dos distúrbios cognitivos na Doença de Parkinson

Cited by 22 publications

References 7 publications

Symptoms of depression in patients with mild cognitive impairment in Parkinson's disease

Symptoms of depression in patients with mild cognitive impairment in Parkinson's disease

Evaluation of functional changes in the evolutionary stages of Parkinson's disease: a case series

Comprometimento Executivo nas Fases Leve à Grave da Doença de Parkinson

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