1996
DOI: 10.1111/j.1939-1676.1996.tb02052.x
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Canine Idiopathic Thrombocytopenic Purpura

Abstract: Canine idiopathic thrombocytopenic purpura (ITP) is a disease in which antibodies bound to the surface of platelets mediate premature platelet destruction by macrophages. ITP in dogs and chronic ITP in humans are analogous diseases. This article draws on information from the literature mmune-mediated thrombocytopenia is a disease in which

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Cited by 88 publications
(164 citation statements)
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References 120 publications
(7 reference statements)
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“…16 It also has a key role in the pathogenesis of CME, as can be observed previously. 17 Although the pathogenesis of acute phase of CME is quite clear, little is known concerning neutrophil function during the course of the disease.…”
Section: Chaffeensissupporting
confidence: 57%
“…16 It also has a key role in the pathogenesis of CME, as can be observed previously. 17 Although the pathogenesis of acute phase of CME is quite clear, little is known concerning neutrophil function during the course of the disease.…”
Section: Chaffeensissupporting
confidence: 57%
“…Thrombocytopenia is considered to be the most common haematological abnormality in dogs infected with E. canis [6,7,9,14]. In .…”
Section: Speed Ehrli Testmentioning
confidence: 99%
“…O paciente foi, então, submetido à esplenectomia, com correção do problema. Na trombocitopenia imunomediada, anticorpos se ligam à superfície de trombócitos, em geral os da classe IgG, e promovem a remoção destes por meio da ação dos macrófagos do sistema retículo-endoplasmático (LEWIS; MEYERS, 1996). A destruição imunomediada de plaquetas ocorre secundariamente a diversas condições, sendo que as doenças infecciosas corresponderam a 31% das causas de trombocitopenia imunomediada secundária em um estudo conduzido por Dircks, Schuberth e Mischke (2009).…”
Section: Parâmetrounclassified