Candida parapsilosis complex in veterinary practice: A historical overview, biology, virulence attributes and antifungal susceptibility traits

Cytotoxic Action of Artemisinin and Scopoletin on Planktonic Forms and on Biofilms of Candida Species

“…They are composed of structural microbial communities adhering to different surfaces and being enveloped by the exopolymeric matrix [1]. Development of biofilms hinders the action of the defense system of the host and increases the resistance to standard antifungal agents [2]. Candida species like Candida albicans (C. albicans), Candida dubliniensis (C. dubliniensis), Candida tropicalis (C. tropicalis), Candida krusei (C. krusei), Candida glabrata (C. glabrata), Candida guilliermondii (C. gulliermondii), and Candida parapsilosis (C. parapsilosis) are fungal species of major medical importance.…”

“…Ar and Sc possess dose-dependent antifungal action but the underlying mechanism type (fungistatic and fungicidal) is not clear yet. Our data suggest that Ar and Sc found in herbal plants might have potential usage in the fight against Candida biofilms.Molecules 2020, 25, 476 2 of 18 infections [2,4,5]. In certain individuals with immune-compromised status, the Candida species might induce consequent infection.…”

“…Molecules 2020, 25, 476 2 of 18 infections [2,4,5]. In certain individuals with immune-compromised status, the Candida species might induce consequent infection.…”

<i>Candida parapsilosis</i> and <i>Candida tropicalis</i> infections in an Okhotsk snailfish (<i>Liparis ochotensis</i>)

“…C . parapsilosis is widely distributed as commensal microorganisms of several healthy animal species and in infections reported in different animal hosts (reviewed by Cordeiro et al [ 7 ]), but it has not been reported in aquatic organisms. The opportunistic Candida spp .…”

Complexo Candida parapsilosis: identificação molecular das espécies, análise proteômica dos biofilmes por MALDI-TOF MS e investigação de um surto envolvendo isolados clínicos resistentes aos azólicos

“…Baixas taxas de resistência ao FLC têm sido relatadas entre os isolados de C. parapsilosis em todo o mundo, incluindo a América Latina (1,1%) (Nucci, Queiroz-Telles, et al, 2013), EUA (4,0%) (Pfaller e Castanheira, 2016), Ásia e Pacífico Ocidental (5,7%) (Pfaller et al, 2015), e Europa (5,6%) (Trouvé et al, 2017). Nos últimos anos, casos de candidíase invasiva causada por isolados NSA têm sido relatados no Brasil (Da Costa et al, 2014;Giacobino et al, 2016;Pinhati et al, 2016;Alencar et al, 2017 As três espécies do complexo C. parapsilosis podem formar biofilme, no entanto, tal capacidade e o tipo de estrutura formada, dependem da cepa envolvida (Cordeiro et al, 2017;Cavalheiro e Teixeira, 2018). Apesar desta dependência, os isolados com maior produção de biofilme são predominantemente de C. parapsilosis (sensu stricto) (Neji, Hadrich, et al, 2017;Paula-Mattiello et al, 2017;Brilhante et al, 2018), enquanto a menor produção tem sido observada principalmente em C. metapsilosis (Cordeiro et al, 2014;Neji, Hadrich, et al, 2017;Brilhante et al, 2018) (Lattif et al, 2010;Melo et al, 2011;Treviño-Rangel et al, 2015), ao demonstrar a falta de relação da biomassa e da viabilidade celular dos biofilmes de C. parapsilosis (sensu lato), ou seja, a atividade metabólica parece ser independente da quantidade de biomassa.…”