Campylobacter fetus ssp. fetus brain abscess

Campylobacter fetus bacteraemia in a healthy individual: clinical and therapeutical implications

“…Central nervous system disease including meningoencephalitis, brain abscesses, cerebrovascular accidents and subarachnoid haemorrhage has also been described. 14,15 Septic arthritis, spontaneous bacterial peritonitis, salpingitis, lung abscess, cellulitis, urinary tract infections, cholecystitis, vertebral osteomyelitis and prosthetic hip joint infection are among the various reported complications of C. fetus bacteraemia. 6,10,[16][17][18][19][20] Nevertheless, almost none of the above has been reported in an immunocompetent individual without any vascular damage.…”

Campylobacterbacteremia: A rare and under-reported event?

“…Remarkably, patients without bacteremia do get hospitalized with Campylobacter-related complications due to the reported presence of these bacteria in cerebrospinal fluid [40], liver [70,71], thyroid gland [72], joints [73], bursitis [74], brain [75], axillary nerve [76], bone [77] and even heart [78,79]. The detection of Campylobacter in these parts of the human body strongly suggests that Campylobacter species are able to travel through the patient's circulatory system without causing actual serious bacteremia that requires hospitalization, at least in the first days of infection.…”

Phenotypic and genetic analyses of two Campylobacter fetus isolates from a patient with relapsed prosthetic valve endocarditis

“…Cff has been well documented to cause a spectrum of systemic illnesses in immunocompromised humans with a tropism for the vascular endothelium, especially at sites of pre-existing damage (Morrison et al 1990). Reported infections include but are not limited to; septic abortion (Hood and Todd 1960), spondylodiscitis (Cunha et al 2021), outbreaks of nosocomial neonatal meningitis (Morooka et al 1988), peritonitis (Wens et al 1985), soft tissue infections (La Scola, Chambourlier and Bouillot 1998), endocarditis (Durovic et al 2021) and other vascular pathologies (vasculitis, pericarditis, thrombophlebitis, mycotic aneurysms, aortitis among others) (Morrison et al 1990;Wagenaar et al 2014;Nulens et al 2018;Eke, Doub and Chua 2021). Persistent (Nakazawa et al 2018), recurrent or relapsed (Tremblay, Gaudreau and Lorange 2003;Tu, Gaudreau and Blaser 2005;Nishikubo et al 2021) and multifocal invasive C. fetus infections (Durovic et al 2021) have also been reported.…”