Calcium orthophosphate bioceramics

Dorozhkin, Sergey V.

doi:10.1016/j.ceramint.2015.08.004

Cited by 200 publications

(81 citation statements)

References 865 publications

(362 reference statements)

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“…Tricalcium bis (phosphate) is the IUPAC (International Union of Pure and Applied Chemistry) name of tricalcium phosphate (TCP). There are also some sources which are describing a phase with the name of tricalcium diorthophosphate beta as one of the polymorphs of TCP (tricalcium phosphate) beta, other names are CaPO 4 tribasic beta or tricalcium bis (orthophosphate) beta [12]. Dorozhkin had also this information given in his 2015-dated report as: "b-tricalcium phosphate [b-Ca 3 (PO 4 ) 2 ".…”

Section: Resultsmentioning

confidence: 99%

Physical Characterization of Turbot (Psetta Maxima) Originated Natural Hydroxyapatite

et al. 2017

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Nowadays hydroxyapatite is one of the most popular biomaterials, which is used in various medical and dental applications areas as graft material. Bovine bone is the biggest source for natural hydroxyapatite production, but its production can lead to very dangerous disease, like mad cow disease, without high degree calcination. Hydroxyapatite produced from marine sources is much safer and easier to produce than bovine hydroxyapatite. Here in this study natural hydroxyapatite and related phases were produced from a local source turbot (Psetta maxima). Beside the main bony internal structure, there are koshers (cycloid scale) on its skin. Koshers are bulky bumps, looking like flat, small and rounded structures. Internal bones and those bulky bumps were cleaned from flesh with chemicals and calcined at 850• C for 4 hours. After calcinations, especially those bulky bumps, were formed into mesoporous structures with very light bluish color. Those mesoporous structures can be used as natural mesoporous hydroxyapatite structures for bone grafting purposes. The internal bones have also formed hydroxyapatite. Scanning electron microscope and X-ray diffraction studies were performed. I this study it is found that the bones of turbot consist of hydroxyapatite and TCP related phases. The aim of this study is to produce natural hydroxyapatite structures from turbot scale with low carbon footprint, without harming the environment and without using complex chemicals.

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Section: Resultsmentioning

confidence: 99%

Physical Characterization of Turbot (Psetta Maxima) Originated Natural Hydroxyapatite

et al. 2017

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“…Therefore there are several names available for this compound such as CaPO4 tribasic beta or tricalcium bis(orthophosphate) beta which is one of the polymorph versions of TCP [14]. In Fig.…”

Section: Resultsmentioning

confidence: 99%

Hydroxyapatite Synthesis from Fish Bones: Atlantic Salmon (Salmon Salar)

et al. 2017

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Production of the bioceramics on the market is presently conducted from typical precipitation method by using reagent grade raw chemicals or through calcination of natural sources like animal bones (especially bovine bone) and fish bones. Usually fish bones were damped near or in the water sources, which can lead to serious environmental pollution. Those were regarded as a trash, even though they still bear economic value, including conjugates. In this study bones of Atlantic Salmon (Salmo salar) were used as a bioceramic material source. Bones of Atlantic Salmon were collected from Besiktas Fish Market. Those were cleaned from possible flesh with reagent grade NaOH. Cleaned parts were washed with demineralized water very neatly. Dry fish bones were calcinated at 850• C for 4 hours. The obtained hydroxyapatite material was characterized with scanning electron microscopy and X-ray diffraction methods. It was found that the bioceramic material consisted of hydroxyapatite and various related phases. Scanning electron microscopy studies have revealed nano-structured bioceramic particles. The aim of this study is to obtain nano-structured bioceramics from bones of Atlantic Salmon in an environmentally friendly and economic way.

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“…Moreover, composites prepared from synthetic HAp and collagen have a great potential to mimic and replace skeletal bones. Biomedical applications of calcium phosphate (CaP) based scaffolds take for example advantage of their ability to induce bone formation and vascularization and to cover varied uses such as bone augmentations, artificial bone grafts, maxillofacial reconstruction, spinal fusion, periodontal disease repairs and bone fillers after tumor surgery [2]. In fact, reconstructive tissue engineering is nowadays a highly active research area that involves the development of materials with outstanding properties.…”

Section: Introductionmentioning

confidence: 99%

“…Hydroxyapatite (HAp, Ca 10 (PO 4 ) 6 (OH) 2 ) is the main inorganic constituent of bone and teeth and therefore has been extensively studied as an artificial bone substitute [1,2]. Moreover, composites prepared from synthetic HAp and collagen have a great potential to mimic and replace skeletal bones.…”

Section: Introductionmentioning

confidence: 99%

Biodegradable and Biocompatible Systems Based on Hydroxyapatite Nanoparticles

et al. 2017

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Abstract:Composites of hydroxyapatite (HAp) are widely employed in biomedical applications due to their biocompatibility, bioactivity and osteoconductivity properties. In fact, the development of industrially scalable hybrids at low cost and high efficiency has a great impact, for example, on bone tissue engineering applications and even as drug delivery systems. New nanocomposites constituted by HAp nanoparticles and synthetic or natural polymers with biodegradable and biocompatible characteristics have constantly been developed and extensive works have been published concerning their applications. The present review is mainly focused on both the capability of HAp nanoparticles to encapsulate diverse compounds as well as the preparation methods of scaffolds incorporating HAp. Attention has also been paid to the recent developments on antimicrobial scaffolds, bioactive membranes, magnetic scaffolds, in vivo imaging systems, hydrogels and coatings that made use of HAp nanoparticles.

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Calcium orthophosphate bioceramics

Cited by 200 publications

References 865 publications

Physical Characterization of Turbot (Psetta Maxima) Originated Natural Hydroxyapatite

Physical Characterization of Turbot (Psetta Maxima) Originated Natural Hydroxyapatite

Hydroxyapatite Synthesis from Fish Bones: Atlantic Salmon (Salmon Salar)

Biodegradable and Biocompatible Systems Based on Hydroxyapatite Nanoparticles

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