Calcium Metabolism and Correcting Calcium Deficiencies

Emkey, Ronald; Emkey, Gregory R.

doi:10.1016/j.ecl.2012.04.019

Cited by 34 publications

(22 citation statements)

References 194 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Another mechanism involves the increase in the stimulation of osteoblasts to express RANKL, thus inducing the differentiation and maturation of preosteoclasts, which then increase the number of osteoclasts and accelerate bone dissolution and resorption. Therefore, continuous low serum calcium levels increase the risk of osteoporosis[77].…”

Section: Discussionmentioning

confidence: 99%

A Hypomagnetic Field Aggravates Bone Loss Induced by Hindlimb Unloading in Rat Femurs

et al. 2014

View full text Add to dashboard Cite

A hypomagnetic field is an extremely weak magnetic field—it is considerably weaker than the geomagnetic field. In deep-space exploration missions, such as those involving extended stays on the moon and interplanetary travel, astronauts will experience abnormal space environments involving hypomagnetic fields and microgravity. It is known that microgravity in space causes bone loss, which results in decreased bone mineral density. However, it is unclear whether hypomagnetic fields affect the skeletal system. In the present study, we aimed to investigate the complex effects of a hypomagnetic field and microgravity on bone loss. To study the effects of hypomagnetic fields on the femoral characteristics of rats in simulated weightlessness, we established a rat model of hindlimb unloading that was exposed to a hypomagnetic field. We used a geomagnetic field-shielding chamber to generate a hypomagnetic field of <300 nT. The results show that hypomagnetic fields can exacerbate bone mineral density loss and alter femoral biomechanical characteristics in hindlimb-unloaded rats. The underlying mechanism might involve changes in biological rhythms and the concentrations of trace elements due to the hypomagnetic field, which would result in the generation of oxidative stress responses in the rat. Excessive levels of reactive oxygen species would stimulate osteoblasts to secrete receptor activator of nuclear factor-κB ligand and promote the maturation and activation of osteoclasts and thus eventually cause bone resorption.

show abstract

Section: Discussionmentioning

confidence: 99%

A Hypomagnetic Field Aggravates Bone Loss Induced by Hindlimb Unloading in Rat Femurs

et al. 2014

View full text Add to dashboard Cite

show abstract

“…Table 3 shows the contribution of açaí consumption for mineral reference dietary intake (RDI), that is, recommended dietary allowances and adequate intakes, as well as the tolerable upper intake levels, according to the Food and Nutrition Board (Institute of Medicine [IOM], 2001). Emphasis should be given to Ca, for which the daily requirement is one of the largest among the essential minerals due to its structural role in the body as the main bone constituent and for other metabolic activities (Emkey and Emkey 2012). A portion of approximately 300 ml açaí pulp is capable of supplying 13-25% of Ca daily needs, which is similar to or greater than the contribution of milk and some dairy products (Food and Drug Administration [FDA], 2010).…”

Section: Determination Of Mineralsmentioning

confidence: 99%

Açaí (Euterpe oleraceaMart.): A Tropical Fruit with High Levels of Essential Minerals—Especially Manganese—and its Contribution as a Source of Natural Mineral Supplementation

Santos

Teixeira

Barbosa

2014

Journal of Toxicology and Environmental Health, Part A

View full text Add to dashboard Cite

Açaí is a fruit from the Brazilian Amazon region, with an exotic flavor, possessing high antioxidant and anti-inflammatory properties. Based on these properties, the fruit is classified as one of the new "super fruits." The mean daily consumption of açai pulp may reach 300 ml in several Brazilian regions. Further, this fruit is also gaining popularity in Europe and North America. In this context, the aim of this study was to assess the levels of some essential minerals in freeze-dried açaí pulp obtained in different Brazilian locations. It was found that açaí pulp is rich in essential minerals (Ca, Fe, Mg, Zn), but the levels of copper (Cu) and especially manganese (Mn) are surprisingly markedly higher than the traditional sources of these elements in the human diet. A daily consumption of 300 ml açaí pulp leads to a Mn daily intake exceeding at least sixfold (14.6 mg on average) the reference daily intake for an adult. Consequently, Mn intake may surpass the permitted daily maximum intake of 11 mg, which leads to a special concern, particularly for children, vegetarians, and individuals with anemia, since iron (Fe) absorption is impaired by Mn. Our findings demonstrate that this fruit is a potential source of several nutrients and a good dietary supplement to resolve malnutrition problems. However, due to the expressive levels of Mn, further studies are necessary to evaluate potential adverse effects associated with açaí consumption.

show abstract

“…HOMEÓSTASIS DE CALCIO El intestino es el principal órgano por donde los iones de calcio ingresan a los compartimentos corporales, por consiguiente, la mucosa intestinal es prácticamente la única barrera biológica para que el calcio ingrese a la circulación portal, y a la circulación sistémica (20,31,34).…”

Section: Globulinaunclassified

“…Ref: (71,65) en forma ionizada (Ca ++ ) o unido a moléculas orgánicas solubles (20,(31)(32)(33)(34).…”

Section: Fuente De Lactosaunclassified

“…La tasa de transporte de calcio del mecanismo celular es saturable y alcanza un valor constante a una cierta concentración de calcio intraluminal. Alternativamente, la tasa de transporte de calcio en el modelo paracelular no es saturable, e incrementa como una función lineal de la concentración soluble del ion, es decir, incrementa con el consumo de calcio dietario soluble (20,31,32).…”

Section: Fuente De Lactosaunclassified

See 1 more Smart Citation

Suero lácteo, generalidades y potencial uso como fuente de calcio de alta biodisponibilidad

Poveda¹

2013

Rev. chil. nutr.

View full text Add to dashboard Cite

El lactosuero o suero de leche se defi ne como un producto lácteo obtenido de la separación del coágulo de la leche, de la crema o de la leche semidescremada durante la fabricación del queso, mediante la acción ácida o de enzimas del tipo del cuajo (renina, enzima digestiva de los rumiantes) (1,2) que rompen el sistema coloidal de la leche en dos fracciones: 1). Una fracción sólida, compuesta principalmente por proteínas insolubles y lípidos, las cuales en su proceso de precipitación arrastran y atrapan minoritariamente algunos de los constituyentes hidrosolubles. 2) Una fracción líquida, correspondiente al lactosuero en cuyo interior se encuentran suspendidos todos los otros componentes nutricionales que no fueron integrados a la coagulación de la caseína (3,5). De esta forma, se encuentran en el lactusuero partículas suspendidas solubles y no solubles (proteínas, lípidos, carbohidratos, vitaminas y minerales), y compuestos de importancia biológica-funcional (6,7).El suero en consecuencia, no constituye un sustituto integral de la leche de vaca por ser una fracción de la misma, pero contiene nutrientes y compuestos con potenciales benefi cios nutricionales y de salud que se aprovechan en algunos países para la fabricación de productos alimenticios y suplementos, o como materia prima para la producción de otros ingredientes, y compuestos. Se observan algunas aplicaciones industriales del suero en la tabla 1.La producción mundial anual de lactusuero en el año Rev

show abstract

Calcium Metabolism and Correcting Calcium Deficiencies

Cited by 34 publications

References 194 publications

A Hypomagnetic Field Aggravates Bone Loss Induced by Hindlimb Unloading in Rat Femurs

A Hypomagnetic Field Aggravates Bone Loss Induced by Hindlimb Unloading in Rat Femurs

Açaí (Euterpe oleraceaMart.): A Tropical Fruit with High Levels of Essential Minerals—Especially Manganese—and its Contribution as a Source of Natural Mineral Supplementation

Suero lácteo, generalidades y potencial uso como fuente de calcio de alta biodisponibilidad

Contact Info

Product

Resources

About