Cactus: a medicinal food

Shetty, Anoop A.; Rana, M.K.; Preetham, S.P.

doi:10.1007/s13197-011-0462-5

Cited by 76 publications

(46 citation statements)

References 37 publications

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“…1 Opuntia ficus-indica (OFI), prickly pear, is a cactus species widely distributed in Latin America, South Africa, and the Mediterranean. It is also utilized in arid and semiarid zones as a fruit, food, and forage crop.…”

Section: Introductionmentioning

confidence: 99%

Antioxidant Opuntia ficus-indica Extract Activates AHR-NRF2 Signaling and Upregulates Filaggrin and Loricrin Expression in Human Keratinocytes

Nakahara

Mitoma

Hashimoto-Hachiya

et al. 2015

Journal of Medicinal Food

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quinone oxidoreductase 1 (NQO1), which inhibited the generation of reactive oxygen species in keratinocytes challenged with tumor necrosis factor α or benzo[α]pyrene. The antioxidant capacity of OFIE was canceled in NRF2 knockdown keratinocytes. OFIE exerted this NRF2-NQO1 upregulation through activation of the aryl hydrocarbon receptor (AHR). Moreover, the ligation of AHR by OFIE upregulated the expression of epidermal barrier proteins: filaggrin and loricrin. OFIE also prevented TH2 cytokine-mediated downregulation of filaggrin and loricrin expression in an AHR-dependent manner because it was canceled in AHR knockdown keratinocytes. Antioxidant OFIE is a potent activator of AHR-NRF2-NQO1 signaling and may be beneficial in treating barrier-disrupted skin disorders.

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Section: Introductionmentioning

confidence: 99%

Antioxidant Opuntia ficus-indica Extract Activates AHR-NRF2 Signaling and Upregulates Filaggrin and Loricrin Expression in Human Keratinocytes

Nakahara

Mitoma

Hashimoto-Hachiya

et al. 2015

Journal of Medicinal Food

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“…Pode ser consumido in natura ou na forma de vinho, suco, geléia, iogurte, doce, conserva e outras sobremesas (HERBACH et al, 2006;SHETTY;RANA;PREETHAM, 2012).…”

Section: Introductionunclassified

Características físicas e físico-químicas de pitaia vermelha durante a maturação

et al. 2015

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ResumoDevido ao aumento do consumo de frutos exóticos mundialmente, o cultivo da pitaia tem sido favorecido. Para incrementar o potencial agronômico da cultura, são necessários conhecimentos que visem o aumento da qualidade do fruto. Dessa forma, objetivou-se nesta pesquisa estudar características físicas e físico-químicas de pitaia vermelha durante a sua maturação, visando definir o estádio ótimo de colheita do fruto. Foram avaliados os seguintes parâmetros de qualidade: massa fresca do fruto, diâmetro longitudinal e transversal, cor de casca, firmeza da polpa, teores de sólidos solúveis, acidez titulável, ratio e pH. O delineamento experimental utilizado foi inteiramente casualizado, representado pelos períodos de coleta (dias após a antese). Em cada período de avaliação foram coletados sete frutos, representando as repetições, sendo um fruto em cada repetição. As médias dos períodos de avaliação foram submetidas à avaliação polinomial, sendo os modelos selecionados conforme a significância do teste F e do coeficiente de determinação. O ponto ideal para a colheita de pitaia vermelha ocorre aos 41 dias após a antese. Neste estádio, os frutos apresentaram maior massa e intensidade de coloração vermelha na casca, menor firmeza da polpa, maior teor de sólidos solúveis e menor acidez. Palavras-chave: Pós-colheita, qualidade de fruto, dias após a antese, Hylocereus undatus Haw AbstractDue to the increase of exotic fruit consumption worldwide, the cultivation of dragon fruit has been favored. To increase the agronomic potential of the culture, knowledge aiming the increase of fruit quality is necessary. The aim of this study was to evaluate the physical-chemical and pyhisical characteristics of dragon fruit during maturation, in order to define the best harvest point. Fresh weight, longitudinal and transverse diameter, skin color, flesh firmness, soluble solids content, titratable acidity, ratio and flesh pH were evaluated. A completely randomized design was carried out, represented by harvest time (days after anthesis). In each evaluation time, seven fruits were harvested, representing the replications, being one fruit per parcel. The averages of each evaluation time were subjected to polynomial evaluation, being selected according to the significance of F test and the coefficient of determination. The best dragon fruit harvest time was observed 41 days after anthesis. At this stage, fruits presented higher weight and higher red skin color intensity, lower flesh firmness, higher contents of total soluble solids and lower acidity.

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“…The Cactaceae family is reported to contain about 1,500 species, which are distributed worldwide (Harlev et al, 2013). Medicinal uses of cacti include antitumor (Loro et al, 1999;Sreekanth et al, 2007;Franco-Molina et al, 2003;Harlev et al, 2013;), anti-inflammatory (Park et al, 1998;Loro et al, 1999), neuroprotective (Kim et al, 2006;Shetty et al, 2012), hepatoprotective (Ncibi et al, 2008), and anti-diabetes (Hassan et al, 2011) activities. An important goal in medicinal plant research is to avoid extensive and repetitive studies on known plants with limited anticancer potential, and focus on promising plants that have not been investigated; the present study was performed following these basic principles.…”

Section: Discussionmentioning

confidence: 99%

“…In the search for alternatives to treat diseases, researchers worldwide have taken the task of finding (Shetty et al, 2012;Harlev et al, 2013;Lema-Rumińska and Kulus, 2014). Pachycereus marginatus (DC.)…”

Section: Introductionmentioning

confidence: 99%

Antitumor activity of Pachycereus marginatus (DC.) Britton Rose extracts against murine lymphoma L5178Y-R and skin melanoma B16F10 cells

Hernandez-Martinez¹,

Gómez-Flores²,

Tamez‐Guerra³

et al. 2016

J. Med. Plants Res.

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Pachycereus marginatus (DC.) Britton & Rose is a species belonging to the family Cactaceae. In traditional medicine, it is recommended to treat diabetes and gastrointestinal infections; however, there are no studies related to its use in cancer treatment. The in vitro antitumor effect of P. marginatus hexane, chloroform, methanol, and methanol-aqueous partition stem extracts, against murine lymphoma L5178Y-R and skin melanoma B16F10 cells, was evaluated in liquid medium by the colorimetric 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT) reduction assay. The extracts resulted in up to 84, 85, 84, and 82% cytotoxicity (p < 0.05) to L5178Y-R cells, respectively, and up to 39, 51, 48, and 42% cytotoxicity (p < 0.05) to B16F10 cells, respectively. Vehicle controls were not cytotoxic for tumor cells, and along with the extracts they did not affect viability of resident murine thymus and spleen lymphocytes. Taken together, the present results showed that P. marginatus extracts possess antitumor potential against L5178Y-R lymphoma and B16F10 skin melanoma cells.

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Cactus: a medicinal food

Cited by 76 publications

References 37 publications

Antioxidant Opuntia ficus-indica Extract Activates AHR-NRF2 Signaling and Upregulates Filaggrin and Loricrin Expression in Human Keratinocytes

Antioxidant Opuntia ficus-indica Extract Activates AHR-NRF2 Signaling and Upregulates Filaggrin and Loricrin Expression in Human Keratinocytes

Características físicas e físico-químicas de pitaia vermelha durante a maturação

Antitumor activity of Pachycereus marginatus (DC.) Britton Rose extracts against murine lymphoma L5178Y-R and skin melanoma B16F10 cells

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