C-dideoxyhexosyl flavones from the stems and leaves of Passiflora edulis Sims

Xu, Feng-Qing; Wang, Cong; Yang, Liping; Fan, Weiwei; Zi, Cheng-Ting; Fan, Dong; Hu, Jiang‐Miao; Zhou, Jun

doi:10.1016/j.foodchem.2012.07.101

Cited by 42 publications

(34 citation statements)

References 20 publications

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“…The 13 C NMR spectrum had six carbon signals assigned at d C 67.1 (C-1 00 ), 31.1 (C-2 00 ), 69.4 (C-3 00 ), 71.1 (C-4 00 ), 72.3 (C-5 00 ) and 17.5 (C-6 00 ). Therefore, the C-linked sugar part was determined to be b-boivinopyranoside (Suzuki et al, 2003;Takeda et al, 2004;Xu et al, 2013), and the HMBC spectrum established that the b-boivinopyranose was linked to C-6 from the correlations of H-1 00 (d H 5.53) to C-5 (d C 160.1), C-6 (d C 114.4) and C-7 (d C 165.0). Based on the above spectroscopic evidence, compound 4 was determined to be 5,7-dihydroxyflavone 6-C-bboivinopyranosyl-7-O-b-D-glucopyranoside.…”

Section: Resultsmentioning

confidence: 99%

Flavonoid glycosides from the aerial parts of Acacia pennata in Myanmar

Kim

Choi

Htwe³

et al. 2015

Phytochemistry

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Section: Resultsmentioning

confidence: 99%

Flavonoid glycosides from the aerial parts of Acacia pennata in Myanmar

Kim

Choi

Htwe³

et al. 2015

Phytochemistry

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“…The derivatives like luteolin 6, 8‐di‐C‐glucoside, luteolin 6‐C‐β‐d‐galactopyranosiduronic acid (1 → 2)‐α‐l‐arabinopyranoside, luteolin 6‐C‐β‐d‐galactopyranosiduronic acid (1 → 2)‐α‐l‐arabinofuranoside, luteolin 6‐C‐glucopyranosyl‐7‐O‐β‐d‐glucopyranoside, and luteolin 6‐C‐α‐L‐arabinopyranose‐7‐O‐β‐D‐glucopyranoside have shown strong antimicrobial activity against respiratory syncytial virus with the cytopathic effect reduction (El‐Toumy et al, ; Wang et al, ). Luteolin 8‐C‐β‐D‐boivinopyranoside has shown neurite outgrowth enhancing activities by enhancing NGF‐induced neurite outgrowth in PC12 cells at a 50.0 μM concentration (Xu et al, ). Luteolin‐4'‐o‐glucoside inhibits melanogenesis in theophylline‐stimulated mouse B16‐4A5 cells.…”

Section: Pharmacological Activities Of Luteolinmentioning

confidence: 99%

Novel extraction techniques and pharmaceutical activities of luteolin and its derivatives

et al. 2019

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Luteolin is a 3′, 4′, 5, 7 tetra hydroxyl flavonoid that exits in many plants, fruits, and vegetable. Many methods of extraction, isolation, and purification are being used, and therapeutic properties are being under discussion due to its valuable role in nutrition and human health. In this review, we have summarized conventional and novel extraction techniques from most recent research on luteolin, its derivatives, and its biological activities. Maceration, soxhlet, reflux, hydrodistillation, ultrasound‐assisted extraction, microwave‐assisted extraction, ultrasound microwave‐assisted extraction, enzyme‐assisted extraction, supercritical fluid extraction, and high‐speed counter‐current chromatography extraction techniques are being used for isolation and purification of these phytochemicals. The anti‐inflammatory, anti‐cancer, antioxidant, antiviral, heart protective, neurological impairments protection, anti‐aging, and whiting properties have been discussed in this review. The literature suggests luteolin and its derivative has many promising health benefits and its therapeutic activity is strongly associated with isolating and purifying solvents and extraction techniques. Practical applications This review aims to highlight the sources, novel extraction techniques, and pharmaceutical properties of luteolin. This review provides enough knowledge about how to get maximum extraction yield of luteolin using the novel extraction techniques. Because its therapeutic activity is strongly associated with isolating and purifying solvents and techniques.

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“…Flavonoids from Passiflora edulis and P. alata have been shown to improve behavioral performance in rats [ 95 ]. The phytochemicals that contribute most to the effects of Passiflora are flavonoids such as apigenin-8- C - β -digitoxopyranoside, apigenin-8- C - β -boivinopyranoside ( Figure 6 ), and luteolin-8- C - β -boivinopyranoside [ 88 ]. Apigenin and its derivatives are known to have anticarcinogenic, antioxidant, and anti-inflammatory properties [ 96 ].…”

Section: Role Of Dietary Phytochemicalsmentioning

confidence: 99%

Phytochemicals That Regulate Neurodegenerative Disease by Targeting Neurotrophins: A Comprehensive Review

Venkatesan

Kim

2015

BioMed Research International

148

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Alzheimer's disease (AD), characterized by progressive dementia and deterioration of cognitive function, is an unsolved social and medical problem. Age, nutrition, and toxins are the most common causes of AD. However, currently no credible treatment is available for AD. Traditional herbs and phytochemicals may delay its onset and slow its progression and also allow recovery by targeting multiple pathological causes by antioxidative, anti-inflammatory, and antiamyloidogenic properties. They also regulate mitochondrial stress, apoptotic factors, free radical scavenging system, and neurotrophic factors. Neurotrophins such as BDNF, NGF, NT3, and NT4/5 play a vital role in neuronal and nonneuronal responses to AD. Neurotrophins depletion accelerates the progression of AD and therefore, replacing such neurotrophins may be a potential treatment for neurodegenerative disease. Here, we review the phytochemicals that mediate the signaling pathways involved in neuroprotection specifically neurotrophin-mediated activation of Trk receptors and members of p75NTR superfamily. We focus on representative phenolic derivatives, iridoid glycosides, terpenoids, alkaloids, and steroidal saponins as regulators of neurotrophin-mediated neuroprotection. Although these phytochemicals have attracted attention owing to their in vitro neurotrophin potentiating activity, their in vivo and clinical efficacy trials has yet to be established. Therefore, further research is necessary to prove the neuroprotective effects in preclinical models and in humans.

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C-dideoxyhexosyl flavones from the stems and leaves of Passiflora edulis Sims

Cited by 42 publications

References 20 publications

Flavonoid glycosides from the aerial parts of Acacia pennata in Myanmar

Flavonoid glycosides from the aerial parts of Acacia pennata in Myanmar

Novel extraction techniques and pharmaceutical activities of luteolin and its derivatives

Phytochemicals That Regulate Neurodegenerative Disease by Targeting Neurotrophins: A Comprehensive Review

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