Buku Ajar Mata Kuliah Organisasi Managemen Industri

Jakaria, Ribangun Bamban

doi:10.21070/2019/978-623-7578-01-7

Cited by 3 publications

(4 citation statements)

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“…Human chondrocytes in 96-well plates were treated with ferroptosis inducer ML-162 (5 µM) [29], inhibitors Fer-1 (1 µM) [31][32][33], DFO (20 µM) [30,34], aTOH (20 µM) [35][36][37], apoptosis inhibitor zVAD-fmk (20 µM) [31,38], and necroptosis inhibitor Nec-1 (20 µM) [39] 30 min before erythrocyte exposure. Post-treatment, cells were stained with Sytox green (2 µM) for fluorescence quantification via a Tecan plate reader.…”

Section: Antagonists For Ferroptosis Apoptosis and Necroptosismentioning

confidence: 99%

Cartilage Destruction by Hemophilic Arthropathy Can Be Prevented by Inhibition of the Ferroptosis Pathway in Human Chondrocytes

Wagener,

Hardt,

Pumberger

et al. 2024

JCM

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(1) Background: Around 50% of hemophilia patients develop severe arthropathy, with even subclinical hemorrhage in childhood potentially leading to intra-articular iron deposition, synovia proliferation, neoangiogenesis, and eventual damage to articular cartilage and subchondral bone. Treatments typically include coagulation factor substitution, radiosynoviorthesis, and joint replacement for advanced cases. This study aims to elucidate programmed cell death mechanisms in hemophilic arthropathy (HA) to identify novel treatments. (2) Methods: Human chondrocytes were exposed to lysed/non-lysed erythrocytes, ferroptosis inducer ML-162, cytokines (IL-1ß, TNFα), and ferric citrate, then assessed for metabolic activity, DNA content, and cell death using Alamar Blue, cyQUANT, and Sytox assays. Three-dimensional spheroids served as a cartilage model to study the effects of erythrocytes and ML-162. (3) Results: Erythrocytes caused significant cell death in 2D cultures (p < 0.001) and damaged 3D chondrocyte spheroids. Iron citrate and erythrocytes reduced chondrocyte DNA content (p < 0.001). The ferroptosis pathway was implicated in cell death, with no effects from apoptosis and necroptosis inhibitors. (4) Conclusions: This study offers insights into HA’s cell death pathway, suggesting ferroptosis inhibitors as potential therapies. Further studies are needed to evaluate their efficacy against the chronic effects of HA.

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Section: Antagonists For Ferroptosis Apoptosis and Necroptosismentioning

confidence: 99%

Cartilage Destruction by Hemophilic Arthropathy Can Be Prevented by Inhibition of the Ferroptosis Pathway in Human Chondrocytes

Wagener,

Hardt,

Pumberger

et al. 2024

JCM

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“…Leadership has a direct impact on organizational performance through the role of employees in the organization (Isa et al, 2019). Leadership in the management function is related to how leaders can influence, direct, motivate, and supervise others to be able to carry out planned tasks to achieve organizational goals and objectives (Jakaria & Putra, 2020).…”

Section: Criteria Validitymentioning

confidence: 99%

Development of the MCDL Day's Instrument as a Personality Measurement Tool compared to the Papikostick Test Tool

Hidayatullah

Thaibah

Maulidina

et al. 2022

JEHCP

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In the working world, the personality of a worker or employee is one of the crucial things to know. Personality can be seen from various things, including behavior patterns, to understand better how someone acts in certain situations. This study looks at the MCDL Day's Instrument as a personality measurement tool compared to the Papikostick test. This research method uses a cross-sectional quantitative approach. The research subjects were 235 people aged 17-34 years. The reliability test used a composite score. The validity test used confirmatory factor analysis (CFA) and concurrent criteria. The results showed that the reliability test of the composite score is 0.616 with the results of the CFA loading factor 0.30 with 18 valid items and four dimensions explaining 23% of the variables. For the criteria validity, there is no significant relationship between the MCDL Day's instrument and the dimensions in Papikostick.

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“…Semua perusahaan secara positif memanfaatkan kualitas ini, namun tidak dijamin untuk memahami dan melibatkan mereka sebagai budaya hierarkis untuk mencapai tujuan perusahaan. Perusahaan Amerika yang pada dasarnya mengembangkan delapan kualitas penting ini, menurut Miller dan rekan-rekannya adalah organisasi yang imajinatif, berguna, dan sukses (Ribangun Bamban, 2019).…”

Section: Definisi Budayaunclassified

“…Dalam gaya kepemimpinan dapat diartikan sebagai perintis berkomunikasi dengan pendukungnya dalam interaksi administrasi (Ribangun Bamban, 2019). Gaya otoritas tersebut sangata penting karena suatu gaya inisiatif akan mencerminkan apa yang akan dilakukan perintis dalam usaha untuk mempengaruhi pendukungnya dengan tujuan ia bisa memahami visinya.…”

Section: Teori Kepemimpinanunclassified

Buku Ajar Manajemen Organisasi dan Sumber Daya Manusia

Jakaria¹,

Sukmono²,

Sumarmi³

2022

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Perubahan kurikulum prodi teknik industri menyebabkaan adanya perubahan MK, yang diikuti perubahan silabus dan SAP sehingga buku ajar manajemen organisasi dan SDM perlu di tulis untuk mendukung pembelajaran yang dilakukan. Buku ajar ini merupakan kombinasi MK. Organisasi Manajemen Industri (2 sks) dan Manajemen Sumber Daya Manusia (2 sks), yang dilebur menjadi MK baru yaitu Manajemen Organisasi dan SDM (4 sks), sehingga dengan berubahan tersebut, SAP masing- masing MK. di gabung dan disesuaikan, sehingga buku ajar ini dimungkinkan menjadi buku ajar yang lengkap yang beda dengan buku ajar lainnya. Sasaran pengguna buku ini adalah Mahasiswa Teknik Industri, sementara sasaran umum adalah Praktisi dan Konsultas SDM serta khalayak yang berkutat pada permasalahan manajemen organisasi dan SDM. Buku ajar ini meruapakan kombinasi 2 mata kuliah yang berbeda serta memiliki capaian pembelajaran yang berbeda pula, sehingga perlunya mempelajari buku ini secara runtut agar tahapan materi yang di susun dapat dipahami. Sistematika buku Manajemen Organisasi dan SDM terdiri atas 10 bab

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Buku Ajar Mata Kuliah Organisasi Managemen Industri

Cited by 3 publications

References 0 publications

Cartilage Destruction by Hemophilic Arthropathy Can Be Prevented by Inhibition of the Ferroptosis Pathway in Human Chondrocytes

Cartilage Destruction by Hemophilic Arthropathy Can Be Prevented by Inhibition of the Ferroptosis Pathway in Human Chondrocytes

Development of the MCDL Day's Instrument as a Personality Measurement Tool compared to the Papikostick Test Tool

Buku Ajar Manajemen Organisasi dan Sumber Daya Manusia

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