Buddlejone, a diterpene from Buddleja albiflora

Protective Effect of Acteoside on Carbon Tetrachloride-Induced Hepatotoxicity

“…1) is a well-studied phenylethanoid glycoside and is widely distributed in medicinal plants. We isolated acteoside from the flowers and buds of Buddleia officinalis (Loganiaceae) which is a traditional medicine used for the treatment of conjunctival congestion, clustered nebulae, and antiseptic (Houghton, 1984;Houghton et al, 1996). Many studies have shown that acteoside has various pharmacological activities, such as anti-tumor (Inoue et al, 1998), anti-oxidant (Xiong et al, 1996;Wong et al, 2001), anti-inflammatory (Schapoval et al, 1998), anti-nephritic (Hayashi et al, 1994), and anti-metastatic (Ohno et al, 2002) activity.…”

Composition and chiral characterization of the essential oil ofBuddleja tucumanensis from Bolivia

“…2,5,6,16 The phytochemistry of B. tucumanensis has not been studied previously, thus as part of our screening programme of the aromatic flora of Bolivia, the purpose of this work was to study the essential oil isolated from the leaves and stems of this species and provide information for its chemical characterization.…”

Nematicidal natural products from the aerial parts ofBuddleja crispa

“…Keeping in view the pharmacological significance of the plant, phytochemical studies were undertaken on the constituents of the aerial parts of the plant in this laboratory two years earlier, which resulted in the isolation and characterisation of various pentacyclic triterpenoids (Houghton, 1989;Houghton et al, 1996). In the present study a bioactivity directed isolation of the ethanolic extract showing nematicidal activity has been undertaken, which resulted in the isolation of two active aromatic compounds.…”

“…No phytochemical investigation has so far been carried out on this species. A literature survey of the genus Buddleja revealed the isolation of various natural products, including sterols (Kapoor et al, 1982;Lopez et al, 1979), aryl esters (Lopez et al, 1979), triterpenoid glycosides (Ding, Yahara, & Nohara, 1992), phenylethanoids (Pardo, Perich, Villrroel, & Torres, 1993), flavonoids (Matsuda, Cai, Kubo, Tosa, & Linuma, 1995), phenolic fatty acid esters (Houghton, 1989), diterpenes (Houghton et al, 1996) and sesquiterpenes (Yoshida, Nobuhara, Uchida, & Okuda, 1976, 1978. Herein, we report the isolation of known compounds (22 R)-stigmasta-7,9 (11)-dien-22 -ol-3 -O--D-galactopyranoside, nonyl benzoate and hexyl p-hydroxycinnamate (Ahmed et al, 2005) along with ginipin (Drewes & Kayonga, 1996), gardiol (Jensen, 1983), 1-heptacosanol (El Khadem & Rahman, 1965), methyl benzoate, galactoside iridoids buddlejosides A and buddlejosides B, and a benzofuran sesquiterpene, buddlejone (Ajaz et al, 2004) along with 3-methoxy-4-hydroxy benzoic acid, and this is the first report of its isolation from this species (Naz, Ahmed, Rasool, Sayeed, & Siddiqi, 2006).…”