Bromophenol Derivatives from the Red Alga Rhodomela confervoides

Zhao, Jielu; Fan, Xiangtao; Wang, Sujuan; Li, Shuai; Shang, Su‐Qin; Yang, Yongchun; Xu, Nianjun; Lü, Yang; Jiangong, Shi

doi:10.1021/np030546+

Cited by 70 publications

(67 citation statements)

References 20 publications

(32 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In this study, the content of phenolic compounds in some of the red algae and in the lichen studied are as high as in brown macroalgae, the microalgal group with the highest reported level of polyphenols (Connan et al 2006, Stengel et al 2011. For example, the content of phenols in the different solvents was 3.2-6.1 mg g -1 DW for Gelidium pusillum, 1.5-4.4 mg g In addition, sulphated phenols and bromophenols have been detected in several species of red macroalgae (Zhao et al 2004). Among the macroalgae, Rhodophyta possess the highest abundance of halogenated phenols (mainly brominated and chlorinated) with antioxidant, antimicrobial, anticancer, antidiabetic, and antithrombotic effects.…”

Section: Discussionmentioning

confidence: 83%

Analysis of antioxidant capacity and bioactive compounds in marine macroalgal and lichenic extracts using different solvents and evaluation methods

2016

View full text Add to dashboard Cite

INTRODUCCIÓNLos organismos marinos, incluyendo las algas y los líquenes, han atraído la atención de muchos investigadores como fuente de compuestos bioactivos debido a sus propiedades, la diversidad de sus moléculas y sus nuevas estructuras químicas que son complejas y difíciles de sintetizar químicamente. Las algas proporcionan una excelente fuente de compuestos bioactivos como carotenoides, polisacáridos, proteínas, lípidos, ácidos grasos, pigmentos, vitaminas, polifenoles y microelementos, entre otras sustancias (Borowitzka Analysis of antioxidant capacity and bioactive compounds in marine macroalgal and lichenic extracts using different solvents and evaluation methods ABSTRACT. Natural extracts of macroalgae are widely recognized for their antioxidant properties. In this work, the antioxidant capacity of various aqueous and hydroalcoholic extracts obtained from red and green marine algae and from one marine lichen collected from different sites in southern Spain (intertidal and estuarine waters) was evaluated by different methods: ABTS free radical scavenging assay, DPPH assay, and β-carotene bleaching method (BBM). Contents of total lipids, total carbohydrates, and UV photoprotectors with antioxidant capacity, such as mycosporine-like amino acids and phenolic compounds, were determined. Among the extraction solvents, the highest extraction yield was observed in H 2 O and 20% MeOH (v/v). The highest antioxidant activity was found in the extracts of the red macroalgae Hydropuntia cornea, Gracilariopsis longissima, Halopithys incurva, and Porphyra umbilicalis, whereas the lowest activity was detected in the green macroalga Ulva rotundata. In general, the antioxidant activity was higher using DPPH than BBM and ABTS. Even so, the ABTS assay is an easy and quick test that provides a comprehensive view of the entire extract in both the lipophilic medium and hydrophilic medium. The antioxidant activity was related to the composition of bioactive compounds and synergistic action is not discarded. The biotechnological use of macroalgal extracts with high antioxidant capacity is discussed.Key words: antioxidants, bioactive compounds, extracts, lichen, macroalgae. RESUMEN.Los extractos naturales de las macroalgas son ampliamente reconocidos por sus propiedades antioxidantes. En este trabajo la capacidad antioxidante de diversos extractos acuosos e hidroalcohólicos obtenidos de algas marinas (rojas y verdes) y de un liquen marino, recolectados en diferentes puntos del sur de España (aguas intermareales y estuarinas), fue evaluada mediante diferentes métodos: método ABTS, ensayo DPPH y método de decoloración del β-caroteno (BBM). Se determinó el contenido de lípidos totales, carbohidratos totales y fotoprotectores de radiación UV con capacidad antioxidante como los aminoácidos de tipo micosporina y compuestos fenólicos. Entre los solventes de extracción, el mayor rendimiento de extracción se observó en los solventes H 2 O y MeOH 20% (v/v). La mayor actividad antioxidante se encontró en los extractos de las macroalgas roj...

show abstract

Section: Discussionmentioning

confidence: 83%

Analysis of antioxidant capacity and bioactive compounds in marine macroalgal and lichenic extracts using different solvents and evaluation methods

2016

View full text Add to dashboard Cite

show abstract

“…Species belonging to the family of Rhodomelaceae are known for their richness in phenolic compounds, especially bromophenols [24,25]. There are no previous reports of antioxidant activity of aqueous and acetone IPS extracts of G.crassa.…”

Section: Discussionmentioning

confidence: 99%

Antioxidant potentials of aqueous and acetone ips extracts of gracilaria crassa

2017

ajbpr

View full text Add to dashboard Cite

Abstract:With the increasing demand of functional foods with antioxidant properties it is necessary to establish new sources such as macro algae which could provide beneficial effects to human health. The present study was evaluated for antioxidant potentials of Gracilaria crassa. Results revealed that Gracilaria crassa significantly recorded the highest IC50 value in acetone than aqueous extracts. Hence it is noteworthy that both aqueous and acetone IPS extracts of Gracilaria crassa hold promising antioxidant potentials.

show abstract

“…Previous studies of Zhao et al 52 reported that the neuroprotective effects of sulforaphane in reducing brain damage, brain edema and protective action of retinal pigment epithet. Sulforaphane has been reported to protect cultured neurons against oxidative stress and dopaminergic neurons against mitochondrial toxins.…”

Section: Sulforaphanementioning

confidence: 95%

Phytochemicals Having Neuroprotective Properties from Dietary Sources and Medicinal Herbs

Kumar¹,

Raghavan²,

Naveen³

2014

Phcog J

View full text Add to dashboard Cite

Many neuropsychiatric and neurodegenerative disorders, such as Alzheimer's disease, anxiety, cerebrovascular impairment, depression, seizures, Parkinson's disease, etc. are predominantly appearing in the current era due to the stress full lifestyle. Treatment of these disorders with prolonged administration of synthetic drugs will lead to severe side effects. In the recent years, scientists have focused the attention of research towards phytochemicals to cure neurological disorders. Nootropic herb refers to the medicinal role of various plants/parts for their neuroprotective properties by the active phytochemicals including alkaloids, steroids, terpenoids, saponins, phenolics, flavonoids, etc. Phytocompounds from medicinal plants play a major part in maintaining the brain's chemical balance by acting upon the function of receptors for the major inhibitory neurotransmitters. Medicinal plants viz. Valeriana officinalis, Nardostachys jatamansi, Withania somnifera, Bacopa monniera, Ginkgo biloba and Panax ginseng have been used widely in a variety of traditional systems of therapy because of their adaptogenic, psychotropic and neuroprotective properties. This review highlights the importance of phytochemicals on neuroprotective function and other related disorders, in particular their mechanism of action and therapeutic potential.

show abstract

Bromophenol Derivatives from the Red Alga Rhodomela confervoides

Cited by 70 publications

References 20 publications

Analysis of antioxidant capacity and bioactive compounds in marine macroalgal and lichenic extracts using different solvents and evaluation methods

Analysis of antioxidant capacity and bioactive compounds in marine macroalgal and lichenic extracts using different solvents and evaluation methods

Antioxidant potentials of aqueous and acetone ips extracts of gracilaria crassa

Phytochemicals Having Neuroprotective Properties from Dietary Sources and Medicinal Herbs

Contact Info

Product

Resources

About