2015
DOI: 10.1111/1346-8138.13162
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Bromoderma mimicking pyoderma gangrenosum caused by commercial sedatives

Abstract: Bromoderma is a rare skin disorder caused by bromide intake. It presents as single or multiple papillomatous nodules or plaques, and ulcers studded with small pustules on the face or limbs. The clinical features of bromoderma are similar to those of pyoderma gangrenosum. A 41-year-old Japanese woman was diagnosed with pyoderma gangrenosum 11 years prior to presentation. Pyoderma had repeatedly appeared over her entire body despite treatment. She also frequently complained of syncopal episodes. She was admitted… Show more

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Cited by 18 publications
(22 citation statements)
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“…Several bromoderma cases reported in the literature are mainly because of systemic therapies with drugs for epilepsy and sedativehypnotic drugs containing inorganic and organic agents, respectively (Jih, Khanna, & Somach, 2003;Maffeis, Musolino, & Cambiaghi, 2008;Oda et al, 2016;Scola, Kaczmarczyk, & Mollenhoff, 2012).…”
Section: Discussionmentioning
confidence: 99%
“…Several bromoderma cases reported in the literature are mainly because of systemic therapies with drugs for epilepsy and sedativehypnotic drugs containing inorganic and organic agents, respectively (Jih, Khanna, & Somach, 2003;Maffeis, Musolino, & Cambiaghi, 2008;Oda et al, 2016;Scola, Kaczmarczyk, & Mollenhoff, 2012).…”
Section: Discussionmentioning
confidence: 99%
“…The histopathologic findings depend on the PG subtype and stage of the disease. 5 Therefore, there are many diseases to be considered in the differential diagnosis of PG such as infections, vasculitis and autoimmune diseases, Sweet syndrome, vascular diseases, and insect bites. 1 The treatment depends on the location, number, and size of the lesions, extracutaneous involvement, the presence of associated diseases, comorbidities, and patient preference.…”
Section: Discussionmentioning
confidence: 99%
“…Therefore, we diagnosed the case as bromoderma because of clinical findings, administration of a bromide-containing drug and elevated blood bromide levels. Hyperchloremia is one of the laboratory findings of bromoderma, 3 but it was normal. He was treated with the discontinuation of bromocriptine and the initiation of oral potassium iodide (0.9 g/day), topical clobetasol propionate ointment and silver sulfadiazine cream.…”
Section: Bromoderma In a Pituitary Adenoma Patient Treated With Bromomentioning
confidence: 99%