Brazilian Phlebotomines as Hosts and Vectors of Viruses, Bacteria, Fungi, Protozoa (Excluding Those Belonging to the Genus Leishmania) and Nematodes

Shaw, Jeffrey Jon; Rosa, Amélia Paes de Andrade Travassos da; Cruz, Ana Cecília Ribeiro; Vasconcelos, Pedro Fernando da Costa

doi:10.1007/978-3-319-75544-1_9

Cited by 5 publications

(4 citation statements)

References 66 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Sand flies (Diptera: Psychodidae: Phlebotominae) are dipterans of medical importance since some species are vectors of Leishmania spp., Bartonella bacilliformis, and some arboviruses. Cosmopolitans, 1047 species are currently known (1014 living and 31 fossils), of which 277 are recorded in Brazil, where about 10% are related as vectors of leishmaniasis [1][2][3][4][5]. Leishmaniasis is a group of diseases caused by parasitic protozoa of the genus Leishmania, which cause clinical manifestations that can compromise the mucosa, skin, and viscera.…”

Section: Introductionmentioning

confidence: 99%

Ecological Aspects of the Phlebotominae Fauna (Diptera: Psychodidae) among Forest Fragments and Built Areas in an Endemic Area of American Visceral Leishmaniasis in João Pessoa, Paraíba, Brazil

Silva

Afonso

Freire

et al. 2022

Insects

View full text Add to dashboard Cite

Sand flies are dipterans of medical importance, as some species are vectors of American visceral leishmaniasis (AVL). The municipality of João Pessoa (Paraíba, northeastern Brazil), is an endemic region for AVL, having high rates of human and canine cases. The main objective was to evaluate the sand fly fauna among forest fragments and built areas, and its relationship with environmental conditions. HP light traps were placed in the studied areas from March 2019 to July 2021. A total of 2141 specimens of phlebotomines were captured, comprising nine genera and ten species. Temperature and humidity were significant and positive only in built areas. The diversity composition among forest fragments and built areas was different and the AVL vector, Lutzomyia longipalpis, was the most prevalent species in built areas. The study showed that the built areas present differences in their richness and diversity of sand flies in relation to forest fragments, concluding that the conservation of forest areas, even if urban fragments, favors the diversity of phlebotomine species.

show abstract

Section: Introductionmentioning

confidence: 99%

Ecological Aspects of the Phlebotominae Fauna (Diptera: Psychodidae) among Forest Fragments and Built Areas in an Endemic Area of American Visceral Leishmaniasis in João Pessoa, Paraíba, Brazil

Silva

Afonso

Freire

et al. 2022

Insects

View full text Add to dashboard Cite

show abstract

“…There is good evidence from the experimental [ 29 ] and natural [ 30 ] infections that Endotrypanum spp. use phlebotomine sand flies as vectors and develop in their hindgut and pylorus, as do L. ( Viannia ) spp.…”

Section: Introductionmentioning

confidence: 99%

“…However, unlike L. ( Viannia ) spp., Endotrypanum can also be detected in Malpighian tubules [ 31 , 32 ]. Endotrypanum schaudinni has been documented in six Brazilian sand fly species [ 30 ], whereas E. colombiensis and E. equatorensis only appear to be vectored by the Panamanian and Ecuadorian Lutzomyia hartmanni [ 19 , 33 ]. Overall, there is evidence of vector specificity, with infection rates varying between species.…”

Section: Introductionmentioning

confidence: 99%

Genome Analysis of Endotrypanum and Porcisia spp., Closest Phylogenetic Relatives of Leishmania, Highlights the Role of Amastins in Shaping Pathogenicity

Albanaz

Gerasimov

Shaw

et al. 2021

Genes

Self Cite

View full text Add to dashboard Cite

While numerous genomes of Leishmania spp. have been sequenced and analyzed, an understanding of the evolutionary history of these organisms remains limited due to the unavailability of the sequence data for their closest known relatives, Endotrypanum and Porcisia spp., infecting sloths and porcupines. We have sequenced and analyzed genomes of three members of this clade in order to fill this gap. Their comparative analyses revealed only minute differences from Leishmaniamajor genome in terms of metabolic capacities. We also documented that the number of genes under positive selection on the Endotrypanum/Porcisia branch is rather small, with the flagellum-related group of genes being over-represented. Most significantly, the analysis of gene family evolution revealed a substantially reduced repertoire of surface proteins, such as amastins and biopterin transporters BT1 in the Endotrypanum/Porcisia species when compared to amastigote-dwelling Leishmania. This reduction was especially pronounced for δ-amastins, a subfamily of cell surface proteins crucial in the propagation of Leishmania amastigotes inside vertebrate macrophages and, apparently, dispensable for Endotrypanum/Porcisia, which do not infect such cells.

show abstract

“…Phlebotomine sand flies (Diptera, Psychodidae) are insects of great medical interest since they can transmit pathogens such as leishmaniases, bartonellosis and some arboviruses [ 2 ] . In the Americas, 547 sand fly species have been recorded, with most in tropical areas.…”

Section: Contextmentioning

confidence: 99%

Sand fly (Diptera: Psychodidae: Phlebotominae) records in Acre, Brazil: a dataset

Godoy¹,

Andrade

Shimabukuro

et al.

Vectors of Human Disease Series

View full text Add to dashboard Cite

Amazonian phlebotomine sand fly fauna is one of the most diverse in the world. The Amazon region is also the most prevalent for leishmaniasis in Brazil and South America. The state of Acre, in this region, also stands out in terms of the diversity of sand fly fauna, as well as the occurrence of American tegumentary leishmaniasis. In this context, the present dataset comprises a bibliographic review of sand fly species recorded in Acre state, Brazil. A total of 1,094 observations from material citations and two of preserved specimens are presented using 33 variables according to Darwin Core terms. The bibliographic review was performed in PubMed, Google Scholar, SciELO, Biblioteca Virtual em Saúde, and references cited in related scientific articles. Thus, this report will be valuable for further studies on sand flies in Acre and other Amazon states.

show abstract

Brazilian Phlebotomines as Hosts and Vectors of Viruses, Bacteria, Fungi, Protozoa (Excluding Those Belonging to the Genus Leishmania) and Nematodes

Cited by 5 publications

References 66 publications

Ecological Aspects of the Phlebotominae Fauna (Diptera: Psychodidae) among Forest Fragments and Built Areas in an Endemic Area of American Visceral Leishmaniasis in João Pessoa, Paraíba, Brazil

Ecological Aspects of the Phlebotominae Fauna (Diptera: Psychodidae) among Forest Fragments and Built Areas in an Endemic Area of American Visceral Leishmaniasis in João Pessoa, Paraíba, Brazil

Genome Analysis of Endotrypanum and Porcisia spp., Closest Phylogenetic Relatives of Leishmania, Highlights the Role of Amastins in Shaping Pathogenicity

Sand fly (Diptera: Psychodidae: Phlebotominae) records in Acre, Brazil: a dataset

Contact Info

Product

Resources

About