Branched polyethylenimine-assisted boronic acid functionalized magnetic nanoparticles for highly efficient capture of lincomycin and clindamycin

Zhang, Yansong; Li, Daojin; Li, Yanhui; Niu, Jiangxiu; Yuan, Ming

doi:10.1039/d3ay00552f

Cited by 2 publications

(1 citation statement)

References 45 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this study, a novel boronic acid ligand, FFPBA, has been used for the first time as a functional monomer, and its pKa value has also been measured for the first time. Although boronic acid functionalized magnetic nanoparticles (MNP) were developed for highly efficient capture of lincomycin (Zhang et al, 2023), the selective ability of the boronic acid functionalized magnetic nanoparticles for Lin was weak due to the absence of an imprinting site. To improve its selectivity and binding, boronate affinity-based imprinted nanoparticles specific to Lin were prepared.…”

Section: Introductionmentioning

confidence: 99%

High-capacity boronate affinity-based template-immobilized surface imprinted silica nanoparticles for rapid, selective, and efficient extraction and determination of lincomycin in milk and chicken

Zhang,

Ding,

et al. 2023

Front. Sustain. Food Syst.

Self Cite

View full text Add to dashboard Cite

BackgroundLincomycin, a natural antibiotic, is widely used by animal and fishery husbandries to prevent infections and treat diseases. It endangers people’s health when they eat foods containing lincomycin residue, especially the frequent consumption of milk and chicken products containing lincomycin. Hence, it is extremely important to evaluate the content of lincomycin in food samples. However, a direct analysis of lincomycin in milk and chicken is quite difficult because of its very low concentration level and the presence of undesirable matrix effects. Therefore, selective and efficient extraction of lincomycin from complex food samples prior to its quantification is required.ResultsIn this study, lincomycin-imprinted silica nanoparticles were prepared according to boronate affinity-based template-immobilized surface imprinting. Silica nanoparticles and boronic acid ligands 3-fluoro-4-formylphenylboronic acid were used as supporting materials and functional monomers, respectively. The prepared lincomycin-imprinted silica nanoparticles exhibited several significant results, such as good specificity, high binding capacity (19.45 mg/g), fast kinetics (6 min), and low binding pH (pH 5.0) toward lincomycin. The reproducibility of lincomycin-imprinted silica nanoparticles was satisfactory. The lincomycin-imprinted silica nanoparticles could still be reused after seven adsorption–desorption cycles, which indicated high chemical stability. In addition, the recoveries of the proposed method for lincomycin at three spiked levels of analysis in milk and chicken were 93.3–103.3% and 90.0–100.0%, respectively.ConclusionThe prepared lincomycin-imprinted silica nanoparticles are feasible for the recognition of target lincomycin with low concentrations in real food samples such as milk and chicken. Our approach makes sample pre-preparation simple, fast, selective, and efficient.

show abstract

Section: Introductionmentioning

confidence: 99%

High-capacity boronate affinity-based template-immobilized surface imprinted silica nanoparticles for rapid, selective, and efficient extraction and determination of lincomycin in milk and chicken

Zhang,

Ding,

et al. 2023

Front. Sustain. Food Syst.

Self Cite

View full text Add to dashboard Cite

show abstract

Monodisperse-porous silica microspheres with flexible phenylboronic acid functionalized-polycationic molecular brushes as a sorbent for teamed boronate affinity chromatography in batch and capillary column systems

Gökçal¹,

Kip²,

Tuncel³

2023

Colloids and Surfaces A: Physicochemical and Engineering Aspect

View full text Add to dashboard Cite

Branched polyethylenimine-assisted boronic acid functionalized magnetic nanoparticles for highly efficient capture of lincomycin and clindamycin

Abstract: As lincosamide antbiotics, lincomycin and clindamycin is widely used in drug manufacturing industry for health of human being and animals. Thus, the content detection of them in real samples is...

Cited by 2 publications

References 45 publications

High-capacity boronate affinity-based template-immobilized surface imprinted silica nanoparticles for rapid, selective, and efficient extraction and determination of lincomycin in milk and chicken

High-capacity boronate affinity-based template-immobilized surface imprinted silica nanoparticles for rapid, selective, and efficient extraction and determination of lincomycin in milk and chicken

Monodisperse-porous silica microspheres with flexible phenylboronic acid functionalized-polycationic molecular brushes as a sorbent for teamed boronate affinity chromatography in batch and capillary column systems

Contact Info

Product

Resources

About