Brain meningioma in a patient with systemic lupus erythematosus

Abstract

Brain meningioma, the most common benign brain tumor, has been reported to account for 13-26% of all intracranial tumors, with a crude incidence rate of 2.3 per 100,000 persons for all types of meningiomas. The prevalence of neuropsychiatric lupus erythematosus is 15-91% and its clinical manifestations are diverse: from mild cognitive dysfunction to serious neurological or psychiatric symptoms. Here, we report the first Korean patient with brain meningioma and systemic lupus erythematosus who had undergone surgical tumor resection.

High-grade spheno-orbital meningioma in patients with systemic lupus erythematosus: Two case reports and literature review

“…is report describes two rare histopathological variants of SOM that occurred in patients with a prolonged history of SLE. e association of meningioma and SLE has been discussed earlier; [10,13,42,49,59] however, no previous report discussed an association of high-grade meningioma and SLE. Meningioma is the most common primary intracranial tumor in adults, accounting for one-third of all primary intracranial tumors, with a female-to-male ratio of 2:1; and most patients have low-grade meningioma.…”

“…[20] From the current literature, we identified eight cases of meningiomas that were reported in patients with SLE. [13,49,59] Histopathological date was available for two patients which determined benign (WHO Grade I) meningiomas. ese reports suggested a possible role of estrogen and progesterone exposure in the pathogenesis of meningioma in those patients.…”