Bone mineral density in children with moderate to severe atopic dermatitis

Velsen, Sara G.A. van; Knol, Mirjam J.; Eijk, Rachel L. A. van; Vroede, Monique A. de; Wit, Tim C. de; Lam, Marnix G. E. H.; Haeck, Inge; Bruin‐Weller, Marjolein S. de; Bruijnzeel-Koomen, Carla A.F.M.; Pasmans, Suzanne G.M.A.

doi:10.1016/j.jaad.2009.12.015

Cited by 36 publications

(34 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…34 The BMD was similar between Dutch children with moderate-to-severe eczema and the general population. 35 Overall, there are limited data regarding BMD in childhood eczema. In this study, children with eczema had similar sonographically measured BMD at the radius and tibia and urinary level of NTx when compared with controls (Table 5).…”

Section: Discussionmentioning

confidence: 99%

Assessment of dietary food and nutrient intake and bone density in children with eczema

et al. 2017

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Assessment of dietary food and nutrient intake and bone density in children with eczema

et al. 2017

View full text Add to dashboard Cite

“…Future studies are needed to determine the relationship between low BMD and fracture history in children with AD. Previous studies of the association of AD in children and adults with low BMD were conflicting (14)(15)(16)(17). An Australian case-control study of 43 children with severe AD and 73 healthy controls found that AD was associated with low BMD, particularly in those who used cyclosporine (14).…”

Section: Discussionmentioning

confidence: 99%

Association between childhood atopic dermatitis, malnutrition, and low bone mineral density: A US population‐based study

Silverberg

2015

Pediatric Allergy Immunology

View full text Add to dashboard Cite

show abstract

“…67 However, when the six patients with cyclosporin were excluded there was no significant difference found between those treated with TCS and the controls. 70 The body location of eczema, vitamin D intake and the use of occlusion with TCS were not examined as potential confounders.…”

Section: Osteopaenia/osteoporosismentioning

confidence: 99%

“…69 The limited research available to date suggests the risk of bone thinning in children with moderate to severe atopic eczema does not appear to differ from the expected prevalence of low BMD in the general population. 70…”

Section: Osteopaenia/osteoporosismentioning

confidence: 99%

Adverse effects of topical corticosteroids in paediatric eczema: Australasian consensus statement

et al. 2015

View full text Add to dashboard Cite

Atopic eczema is a chronic inflammatory disease affecting about 30% of Australian and New Zealand children. Severe eczema costs over AUD 6000/year per child in direct medical, hospital and treatment costs as well as time off work for caregivers and untold distress for the family unit. In addition, it has a negative impact on a child's sleep, education, development and self-esteem. The treatment of atopic eczema is complex and multifaceted but a core component of therapy is to manage the inflammation with topical corticosteroids (TCS). Despite this, TCS are often underutilised by many parents due to corticosteroid phobia and unfounded concerns about their adverse effects. This has led to extended and unnecessary exacerbations of eczema for children. Contrary to popular perceptions, (TCS) use in paediatric eczema does not cause atrophy, hypopigmentation, hypertrichosis, osteoporosis, purpura or telangiectasia when used appropriately as per guidelines. In rare cases, prolonged and excessive use of potent TCS has contributed to striae, short-term hypothalamic-pituitary-adrenal axis alteration and ophthalmological disease. TCS use can also exacerbate periorificial rosacea. TCS are very effective treatments for eczema. When they are used to treat active eczema and stopped once the active inflammation has resolved, adverse effects are minimal. TCS should be the cornerstone treatment of atopic eczema in children.

show abstract

Bone mineral density in children with moderate to severe atopic dermatitis

Cited by 36 publications

References 37 publications

Assessment of dietary food and nutrient intake and bone density in children with eczema

Assessment of dietary food and nutrient intake and bone density in children with eczema

Association between childhood atopic dermatitis, malnutrition, and low bone mineral density: A US population‐based study

Adverse effects of topical corticosteroids in paediatric eczema: Australasian consensus statement

Contact Info

Product

Resources

About