1982
DOI: 10.1001/jama.1982.03330080031024
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Body Weight and Subsequent Diabetes Mellitus

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Cited by 159 publications
(68 citation statements)
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“…O'Sullivan originally projected that 50% of patients with GDM would develop diabetes in a follow-up study of 22-28 years. 5 The progression to type 2 DM may be influenced by ethnicity and the profound increased incidence of obesity in the U.S. population in recent years. For example, 60% of Latina women with GDM will develop type 2 DM, and this level of risk may actually be manifest by 5 years after the GDM index pregnancy.…”
Section: Screening and Diagnosismentioning
confidence: 99%
See 1 more Smart Citation
“…O'Sullivan originally projected that 50% of patients with GDM would develop diabetes in a follow-up study of 22-28 years. 5 The progression to type 2 DM may be influenced by ethnicity and the profound increased incidence of obesity in the U.S. population in recent years. For example, 60% of Latina women with GDM will develop type 2 DM, and this level of risk may actually be manifest by 5 years after the GDM index pregnancy.…”
Section: Screening and Diagnosismentioning
confidence: 99%
“…69 O'Sullivan's original cohort of women with former GDM indicated a prevalence of diabetes of 50 -60% at 28 years of follow-up. 5 70 Abnormal carbohydrate intolerance may persist in the postpartum period depending on the population studied and its associated risk factors. As many as one-third of women with GDM will have overt diabetes, impaired fasting glucose, or impaired glucose tolerance identified during postpartum testing conducted within 6 -12 weeks of delivery.…”
Section: Postpartum Follow-up and Prevention Of Type 2 Diabetesmentioning
confidence: 99%
“…11,12 Furthermore, it has been long known that women with a history of gestational diabetes, as compared with their counterparts without such a reproductive history, are at increased risk of developing type 2 diabetes overall. 13,14 In a case-control study of 67 women with gestational diabetes and 260 controls, we observed that maternal intrapartum plasma ascorbic acid concentrations were 31% lower for cases than controls on average (mean Ϯ standard error ϭ 36.5 Ϯ 2.0 vs. 53.0 Ϯ 1.0 mol/L). We also found that women with plasma ascorbic acid concentrations below 42.6 mol/L experienced a 13-fold (95% CI ϭ 3.5-46.2) increased risk of gestational diabetes as compared with women with values above 63.3 mol/L.…”
mentioning
confidence: 93%
“…However, women who are obese during pregnancy and develop gestational diabetes have been shown to have a 2-fold increased prevalence of subsequent type 2 diabetes as compared to lean women. 27 Therefore, maternal obesity is a significant long-term risk factor for type 2 diabetes. 28 The association between obesity and hypertensive disorders during pregnancy has been a consistent finding in the obstetrical literature (Table 2).…”
mentioning
confidence: 99%