Body composition and metabolic profile in adults with vitamin D deficiency

Rocha, Liane Murari; Baldan, Daniela Cristina da Silva; Souza, Aglécio Luiz de; Chaim, Élinton Adami; Pavin, Elizabeth João; Alegre, Sarah Monte

doi:10.1590/1678-98652017000400002

Cited by 16 publications

(19 citation statements)

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“…In the specific case of Brazil, although it is a tropical country with a year-round incidence of solar radiation, a significant prevalence of 25(OH)D deficiency has also observed [14,15]. Recent evidence confirms similar findings in other populations around the world [16,17] that rekindles the question of which factors could be associated with a lower serum 25(OH)D levels in the adult population.…”

Section: Introductionmentioning

confidence: 59%

“…Blood samples were collected using a vacuum-assisted blood collection system and disposable material after 12 hours of fasting. The status of 25(OH)D was determined according to the following reference values: sufficient (≥30.0ng/ml), insufficient (21.0ng/ml to 29.9ng/ml) and deficient (≤20.9ng/ml) [14,26]. The season of the year when blood collection was performed was also evaluated and categorized as: winter, autumn, spring and summer.…”

Section: E T H O D Smentioning

confidence: 99%

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Excessive abdominal adiposity and body fat are associated with lower serum vitamin D levels: A population-based study

et al. 2018

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Objective To estimate the prevalence of 25-hydroxyvitamin D deficiency and to analyze factors associated with lower serum vitamin levels in Brazilian adults. Methods A cross-sectional, population-based study consisted of 626 adult individuals of both sexes living in the urban area of Viçosa, Minas Gerais. The dependent variable used was the serum level of 25-hydroxyvitamin D and the independent variables were sociodemographic, anthropometric and body composition variables. The associations among the variables were verified using simple and multiple linear regression models, considering alpha lower than 0.05 for the input in the final model. Results The prevalence of 25-hydroxyvitamin D deficiency was 14.4% and the prevalence was 42.0%. Excess abdominal fat was higher in subjects with 25-hydroxyvitamin D sufficiency. The serum level of 25-hydroxyvitamin D was 30.34±9.85ng/ml. Body adiposity was higher in men with vitamin insufficiency. Negative associations were observed between serum 25-hydroxyvitamin D levels and age, educational level, body adiposity (p=0.028) and abdominal adiposity (p=0.023). Conclusion Our results showed that excess body and abdominal adiposity are strong predictors of alterations in the serum vitamin D levels, thus public policies for prevention and treatment in this population are essential.

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Section: Introductionmentioning

confidence: 59%

Section: E T H O D Smentioning

confidence: 99%

Excessive abdominal adiposity and body fat are associated with lower serum vitamin D levels: A population-based study

et al. 2018

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“…Analysis by Rocha LM et al . [14] in a cross-sectional study of 106 adults of both genders vitamin D deficiency had higher triglycerides, VLDL, fasting blood glucose, insulin, glycated hemoglobin, BMI, waist circumference, and HOMA-IR than those of the vitamin D sufficient group ( P < 0.05)…”

Section: Discussionmentioning

confidence: 99%

Pandemic of Vitamin D deficiency: Cardiometabolic concern or skeletal biochemical abnormality?

Mukhopadhyay¹,

Ghosh²,

Pandit³

et al. 2019

Indian J Endocr Metab

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Context: Biochemical Vitamin D deficiency is said to be present universally in recent times. However, its effect is more profound in modulation of anthropometric and biochemical risk factors of various chronic metabolic disorders rather than its influence on bone mineral abnormalities. The present study was undertaken to compare various anthropometric and biochemical parameters including basic bone mineral biochemistry in various strata of Vitamin D status. Materials and Methods: A population based study was done in the rural area of West Bengal comprising 405 people (initially targeted 400) to look for various anthropometric and biochemical parameters. Results: Anthropometric metabolic markers like BMI, WC, waist to height ratio and biochemical parameters like total cholesterol, LDL, TG, insulin, ALT, FPG were statistically significantly higher in vitamin D deficient (<20 ng/ml) ( n = 228) subjects compared to Vitamin D non-deficient subjects (≥20 ng/ml) ( n = 177) which persisted even after adjustment for BMI except for FPG. The difference was similarly present when severely Vitamin D deficient (<10 ng/ml) ( n = 39) subjects were compared to Vitamin D sufficient subjects (≥30 ng/ml) ( n = 38) and persisted after adjustment for BMI except for FPG. However, WHR, blood pressure (both systolic and diastolic), HbA1c, HDL, AST, Uric acid, freeT4, TSH, HOMA-IR were not different in both the above-mentioned comparisons. Metabolic syndrome was statistically significantly lower in vitamin D non-deficient subjects. Though iPTH was statistically significantly higher in the low vitamin D cohorts in both the comparisons, bone mineral markers like serum calcium, phosphorus and alkaline phosphatase were not different even when severely vitamin D deficient subjects were compared to vitamin D sufficient subjects. Conclusion: Pandemic of vitamin D deficiency is more likely to be associated with cardio-metabolic risk factors than biochemical bone mineral abnormality.

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“…Therefore, there is a growing need for studies that include as many risk factors as possible. [16][17] Researchers from China conducted a comprehensive review of the literature and a meta-analysis to assess the association between serum levels and dietary intake of vitamin D with the risk of lung cancer. As a result, they found that those with higher serum vitamin D levels had a 16% lower risk of developing lung cancer.…”

Section: Methods Introductionmentioning

confidence: 99%

Impacto da vitamina d na prevenção do câncer pulmonar e brônquico

Cruz

Silva

2018

Rev enferm UFPE on line.

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RESUMOObjetivo: identificar evidências de ação preventiva da vitamina D sobre a taxa de mortalidade de câncer de pulmão e de brônquios da população brasileira. Método: estudo quantitativo, epidemiológico, descritivo, desenvolvido a partir da coleta de dados das fontes INCA e IBGE. Os dados do INCA revelavam taxas de mortalidade para os dois cânceres, enquanto que o IBGE disponibilizava latitudes específicas de todas as capitais do país. Após a coleta, os dados foram digitados no programa Microsoft Excel, posteriormente, transferidos para o programa de construção de mapas Target Map e analisados por meio de estatística descritiva. Resultados: observou-se que as cinco unidades federativas mais distantes da linha do Equador representam as maiores taxas de mortalidade do Brasil comum em ambos os sexos. Conclusão: os resultados evidenciam uma ação preventiva da vitamina D nas regiões mais ensolaradas do país e que esta substância pode ser um recurso transformador de saúde pública. Contudo, há grande necessidade de estudos multicêntricos para maior respaldo científico. Descritores: Vitamina D; Neoplasias Pulmonares; Neoplasias Brônquicas; Prevenção de Doenças; Aplicações da Epidemiologia; Registros de Mortalidade.ABSTRACT Objective: to identify evidence of preventive action of vitamin D on the mortality rate of lung and bronchial cancer in the Brazilian population. Method: quantitative, epidemiological, descriptive study, developed from data collection from INCA and IBGE sources. The INCA data revealed mortality rates for both cancers, while the IBGE provided specific latitudes of all the capitals of the country. After the data collection, the data was entered in the Microsoft Excel program, later transferred to the program of construction of maps of the Target Map and analyzed by means of descriptive statistics. Results: it was observed that the Five most distant federative units of the Equator line represent the highest mortality rates of Brazil, common in both sexes. Conclusion: the results show the preventive action of vitamin D in the sunniest regions of the country and that this substance can be a transformative resource of public health. However, there is a great need for multicenter studies for greater scientific support. Descriptors: Vitamin D; Lung Neoplasms; Bronchial Neoplasms; Disease Prevention; Uses of Epidemiology; Mortality Registries.RESUMEN Objetivo: identificar evidencias de acción preventiva de la vitamina D sobre la tasa de mortalidad de cáncer de pulmón y de bronquios de la población brasileña. Método: estudio cuantitativo, epidemiológico, descriptivo, desarrollado a partir de la recolección de datos de las fuentes Inca e IBGE. Los datos del INCA revelaban tasas de mortalidad para los dos cánceres, mientras que el IBGE disponía de latitudes específicas de todas las capitales del país. Después de la recolección, los datos fueron digitados en el programa Microsoft Excel, posteriormente, transferidos al programa de construcción de mapas Target Map y siendo analizados por medio de estadística descriptiva. Resultados: se observó que las cinco unidades federativas más distantes de la línea del Ecuador representan las mayores tasas de mortalidad de Brasil, siendo común en ambos sexos. Conclusión: los resultados evidencian una acción preventiva de la vitamina D en las regiones más soleadas del país y que esta sustancia puede ser un recurso transformador de salud pública. Sin embargo, hay gran necesidad de estudios multicéntricos para mayor respaldo científico. Descriptores: Vitamina D; Neoplasias Pulmonares; Neoplasias de los Bronquios; Prevención de Enfermedades; Usos de la Epidemiología; Registros de Mortalidad.

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Body composition and metabolic profile in adults with vitamin D deficiency

Cited by 16 publications

References 50 publications

Excessive abdominal adiposity and body fat are associated with lower serum vitamin D levels: A population-based study

Excessive abdominal adiposity and body fat are associated with lower serum vitamin D levels: A population-based study

Pandemic of Vitamin D deficiency: Cardiometabolic concern or skeletal biochemical abnormality?

Impacto da vitamina d na prevenção do câncer pulmonar e brônquico

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