“…Glioma is a kind of CNS tumor developed from the deterioration of glial cells, which is one of the tumors with the highest degree of human evil (Molinaro et al, 2019). At present, the main treatment T A B L E 4 (Continued) (Continues) methods for glioma are surgical resection, chemotherapy, and radiotherapy; however, due to its invasive growth, it is difficult to be completely removed by surgery, and radiotherapy and chemotherapy usually achieve poor results and are often accompanied by serious side effects (Du et al, 2018;Suehiro et al, 2018). In recent years, the discovery of natural antitumor monomer drugs, such as paclitaxel and ginsenoside, made the anticancer effect of natural constituents to be gradually paid more and more attention (Kim et al, 1999;Yu et al, 2015).…”