1993
DOI: 10.1039/ft9938900539
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block-Copoly(oxyethylene/oxybutylene/oxyethylene), E40B15E40, in aqueous solution: micellisation, gelation and drug release

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Cited by 56 publications
(44 citation statements)
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“…9 It is worth mentioning that this behaviour is shown also by other amphiphilic block copolymers of PEG. 10,11 Early observations demonstrated an almost athermal character of Pluronic gelation (contrary to micellization) 12 and the substantial absence of a driving force based on hydrogen bonding, 13 suggesting that micelles are still present and substantially unaltered in the gels. In solvents selective for one block, micellar gels of block copolymers often show a cubic morphology, and this is indeed also the case for most PEG-containing block copolymers.…”
Section: Introductionmentioning
confidence: 99%
“…9 It is worth mentioning that this behaviour is shown also by other amphiphilic block copolymers of PEG. 10,11 Early observations demonstrated an almost athermal character of Pluronic gelation (contrary to micellization) 12 and the substantial absence of a driving force based on hydrogen bonding, 13 suggesting that micelles are still present and substantially unaltered in the gels. In solvents selective for one block, micellar gels of block copolymers often show a cubic morphology, and this is indeed also the case for most PEG-containing block copolymers.…”
Section: Introductionmentioning
confidence: 99%
“…Compared with the typical low-molecular-weight surfactants, Pluronic copolymers have superior properties, such as extremely low critical micelle concentrations (CMC), a large diversity in molecular characteristics (PPO/PEO ratio, molecular weight) and microstructures, and, as a result, rich amphiphilic properties (8) and a very low toxicity (9). PEO-PPO-PEO block copolymers have widespread industrial applications in biology, medicine, cosmetics, and textiles (10)(11)(12). Therefore, theoretical and practical research on the properties of Pluronic copolymers in aqueous solu-tions is arousing increasing interest (13,14).…”
mentioning
confidence: 99%
“…Any substantial or systematic reproduction, redistribution, reselling, loan, sub-licensing, systematic supply, or distribution in any form to anyone is expressly forbidden. [10] Poly(ethylene oxide)-block-poly(propylene-oxide)-blockpoly(ethylene oxide) block copolymers have found widespread industrial applications in biology, medicine, cosmetics, textile, [11][12][13] and so on. Compared with typical low-molecular-weight surfactants, Pluronic copolymers have superior properties, such as an extremely low critical micelle concentration (CMC), a large diversity in the molecular characteristics (PPO=PEO ratio, molecular weight) and microstructures, and as a result, rich amphiphilic properties [9] and very low toxicity.…”
mentioning
confidence: 99%