Photopolymerization of Pluronic F127 diacrylate: a colloid-templated polymerization

Biase, Manuela Di; Leonardis, Piero De; Castelletto, Valeria; Hamley, Ian W.; Derby, Brian; Tirelli, Nicola

doi:10.1039/c1sm05095h

Cited by 42 publications

(52 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…GC = gel content of hydrogels; Q = equilibrium degree of swelling of ABA hydrogels. This result is remarkable, as in previous reports polymerization of 13K-OEG70 resulted in cross linked colloids instead of hydrogel networks (17).…”

Section: Gcsupporting

confidence: 88%

Hydrogel Networks Based on Aba Triblock Copolymers

Tartivel

Behl

Schroeter

et al. 2012

Journal of Applied Biomaterials & Functional Materials

View full text Add to dashboard Cite

Although OEG-OPG-OEG triblocks are known for their micellization, which could hamper polymer network formation, reactive OEG-OPG-OEG triblock oligomers could be successfully polymerized into hydrogel networks. The degree of swelling of these hydrogels depends on their molecular weight and on the oligomer concentration used for hydrogel preparation. In combination with the temperature sensitivity of the ABA triblock copolymers, it is assumed that such hydrogels might be beneficial for future medical applications - e.g., removable drug release systems.

show abstract

Section: Gcsupporting

confidence: 88%

Hydrogel Networks Based on Aba Triblock Copolymers

Tartivel

Behl

Schroeter

et al. 2012

Journal of Applied Biomaterials & Functional Materials

View full text Add to dashboard Cite

show abstract

“…org/) with a layer height of 0.204 mm, making up 40% of the nozzle diameter. Dispensing was performed with a Hyrel 3D System 30 device with dispensing speeds of 8 mm s 21 and an inner nozzle diameter of 0.51 mm. The robotic dispensing device was operated using the software Repetrel.…”

Section: Methodsmentioning

confidence: 99%

“…Thus, polymers like gelatin methacrylamide or acrylated P407 were processed successfully by robotic dispensing and cured to chemical hydrogels afterwards by photopolymerization of the acrylic groups. In the case of acrylated P407, both the physical gelation and chemical gelation are a property of only one component in the hydrogel formulation …”

Section: Introductionmentioning

confidence: 99%

“…In the case of acrylated P407, both the physical gelation and chemical gelation are a property of only one component in the hydrogel formulation. 10,21 Many solutions of frequently used hydrogel building blocks such as poly(ethylene glycol) diacrylate (PEG-DA) cannot be processed by robotic dispensing because they are relatively low viscosity liquids. However, PEG-DA based hydrogels are frequently used in biomaterial science because they are non-toxic and can be easily chemically modified.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Influence of shear thinning and material flow on robotic dispensing of poly(ethylene glycol) diacrylate/poloxamer 407 hydrogels

Kraut

Yenchesky

Prieto

et al. 2017

J of Applied Polymer Sci

View full text Add to dashboard Cite

Robotic dispensing of hydrogels offers a direct way for generating complex hydrogel shapes. For this, there is a general need for hydrogel formulations with suitable rheological properties. In this contribution, hydrogel formulations containing poly(ethylene glycol) diacrylate (PEG‐DA) and Poloxamer 407 are characterized regarding their flow behavior during robotic dispensing. Formulations contain between 15% and 20% PEG‐DA and 22.5% and 25% Poloxamer 407. All formulations show shear thinning which can be described using a power law with a power law index between 0.10 and 0.11 and calculated shear rates at the wall of the dispensing needle of 379 s−1 with a dispensing speed of 8 mm s−1 and a dispensing needle inner diameter of 0.51 mm. Thus, facilitating the generation of smooth hydrogel strands, three‐dimensional hydrogel objects can be prepared without flow after robotic dispensing and can be cured afterward to elastic hydrogels, retaining the shape of the dispensed object. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 45083.

show abstract

“…23 However, there exists no report on the precise control, with external stimuli, of the swelling behavior of this (co)polymer, in its hydrogel form. Important to note is that since the thermoresponsive of PF127 has been extensively reported, [24][25][26] but it will not be investigated here.…”

Section: Introductionmentioning

confidence: 99%

Properties of electrically responsive hydrogels as a potential dynamic tool for biomedical applications

Adesanya

Vanderleyden

Embrechts

et al. 2014

J of Applied Polymer Sci

View full text Add to dashboard Cite

Hydrogels with electric responsive properties are gaining research focus due to increasing demand for miniaturized devices that can be precisely controlled using an external stimulus. Such systems are well suited due to their ability to expand and contract when in contact with different types of fluid. This study reports on the synthesis of a "smart" electroresponsive network, using a neutral, "non-smart," biocompatible hydrogel forming building block, Pluronic F127 (PF127), as a starting molecule. The PEO-PPO-PEO copolymer was modified with telechelic methacrylic end functionalities to form a triblock linear prepolymer with crosslinkable end groups (crosslinker). This bifunctional prepolymer, PF127 bismethacrylate (PF127BMA), was copolymerized covalently with anionic methacrylic acid sodium salt groups into a nonsoluble 3D hydrogel network in the presence of redox initiators. The polyelectrolyte domains in the pluronic hydrogel afforded controllable swelling capabilities with volumetric expansion exceeding 8500% in deionized water or 1400% in Krebs solution. The hydrogels were further assessed for their mechanical and electroactive response as a function of increasing acid salt content.

show abstract

Photopolymerization of Pluronic F127 diacrylate: a colloid-templated polymerization

Cited by 42 publications

References 34 publications

Hydrogel Networks Based on Aba Triblock Copolymers

Hydrogel Networks Based on Aba Triblock Copolymers

Influence of shear thinning and material flow on robotic dispensing of poly(ethylene glycol) diacrylate/poloxamer 407 hydrogels

Properties of electrically responsive hydrogels as a potential dynamic tool for biomedical applications

Contact Info

Product

Resources

About