Birth weight, Apgar score, and fetal complications in mothers with severe preeclampsia

Sirenden, Heldayanti; Sunarno, Isharyah; Arsyad, Aryadi; Idris, Irfan

doi:10.1016/j.enfcli.2019.07.154

Cited by 6 publications

(4 citation statements)

References 14 publications

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“…In our study, Apgar score was substantially less in PE with IUGR compared to PE without IUGR, also PE in comparison to controls had significantly lower Apgar. This agrees with the research by Sirenden et al, that found that severe PE cases had considerably lower Apgar scores, birth weight (14) . This contrasts the study of AL-Bayati et al, which examined the impact of preeclampsia on the number of nucleated red blood cells in maternal and cord blood as a sign of fetal impairment.…”

Section: Resultssupporting

confidence: 93%

A New Predictor for Growth Restriction in Preeclampsia. A Case Control Study

Gad¹,

El-Barbary²,

Ismail³

et al. 2023

The Egyptian Journal of Hospital Medicine

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Background: Preeclampsia(PE) is culpable of the placental hypoxia that persists during pregnancy. The number of nucleated red blood cells in the cord blood (cNRBCs) is a sign of a hypoxic fetal environment. It might be a potential indication of intra-uterine growth restriction (IUGR). Objective: The goal is to ascertain whether pre-eclampsia is related to an increase in the number of cNRBCs in cord blood, especially those with restricted growth. Methods: This case control study was conducted on 150 neonates who were divided into three equal groups; group I included newborns of PE women, without IUGR, group II included newborns of PE women, with IUGR and group III included apparently healthy newborns of healthy non-PE pregnant women as a control group. As soon as the cord was clamped, samples for complete blood count and blood gases were taken from the umbilical vein. Results: cNRBCs count was significantly higher in group with PE and IUGR compared to PE without IUGR and the control groups. The cutoff value of cNRBC to discriminate newborns of healthy mothers and those with PE was ≥ 8 cNRBCs/100 WBCs. Yet the value to discriminate newborns of PE mothers with IUGR and without IUGR was ≥ 22 NRBCs/100 WBCs. Conclusion: When PE was compared to controls, it was discovered that cNRBCs were considerably greater. Moreover, higher cNRBCs was found in PE with IUGR compared to PE without IUGR. Thus, cNRBCs count has predictive value for IUGR. It may be used to tell growth-restricted babies from small-for-their-age children.

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Section: Resultssupporting

confidence: 93%

A New Predictor for Growth Restriction in Preeclampsia. A Case Control Study

Gad¹,

El-Barbary²,

Ismail³

et al. 2023

The Egyptian Journal of Hospital Medicine

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“…The present study showed that FGR is much more prevalent in the preeclamptic group than in the preeclamptic group (30.1% vs. 9.6%). In this study, neonates of preeclamptic mothers were 3.7 times more likely to have FGR than neonates of non-preeclamptic mothers, consistent with a recent cohort study in Germany (22), resulting from impaired uteroplacental blood flow. Preeclampsia and FGR are known to be associated with placental infarctions; therefore, they are likely to be related (23,24).…”

Section: Discussionsupporting

confidence: 91%

“…neonates of preeclamptic mothers had low birth weight (22). As gestational age at birth significantly affects birth weight, preeclampsia results in an earlier delivery, resulting in a lower birth weight rate.…”

Section: Discussionmentioning

confidence: 99%

Neonatal Outcomes of Severe Preeclampsia in Neonates Under 34 Weeks of Gestation

Sharami,

Kabodmehri,

Rafiei Sorouri

et al. 2023

J Kermanshah Univ Med Sci

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Background: Preterm birth is one of the common complications of preeclampsia. Neonatal outcomes seem to be more severe in the presence of preeclampsia in women with preterm birth. Objectives: This study aimed to evaluate the effect of preeclampsia on morbidity and mortality of neonates under 34 weeks of gestation at discharge. Methods: This retrospective cohort study was conducted on 311 neonates admitted to the Alzahra Tertiary Care Hospital from 2019 to 2021. Data were collected using a data extraction checklist from the medical registry. The data analysis included descriptive statistics, Chi-square, and Fisher's exact test. Multiple logistic regression was used to identify the neonatal outcomes of preeclampsia. Results: Logistic regression analysis showed that risk of cesarean section (P = 0.002, OR = 2.81), low birth weight (P = 0.018, OR = 4.04), fetal growth restriction (< 0.001, OR = 3.73), fetal distress (P = 0.005, OR = 2.60), and mortality (P = 0.019, OR = 2.89) was higher in women with severe preeclampsia after adjusting for maternal age, history of In vitro fertilization, neonate sex, and gestational age. Conclusions: Based on the results, preeclampsia increased the risk of neonatal morbidity and mortality in preterm neonates under 34 weeks. Therefore, early identification of pregnant women at risk of preeclampsia is crucial. Future studies are recommended to investigate the long-term neonatal outcomes of preeclampsia.

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“…However, they were downwardly affected in preeclampsia patients. We did not observe a significant difference in apgar scores in both PE group and the patients with increased MPFD as Sirenden et al reported (16). We also found that umbilical-cord blood gas pH values were lower, and the base deficit was higher in the preeclampsia group as Sheikh et al found (17).…”

Section: Discussionsupporting

confidence: 49%

Can Placental Histopathological Lesions Be a Guide to Maternal and Neonatal Outcomes in Patients With Preeclampsia?

Atıgan¹,

Kılıç²,

Güler³

et al. 2022

jmed

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Objective: The aim of this study was to investigate the predictive role of massive perivillous fibrinoid deposition (MPFD), syncytial knots, and accompanying histopathological features of placentas of preeclampsia (PE) on maternal and neonatal outcomes. Matherials and Methods:A retrospective clinicopathological study was conducted in a tertiary unit. In the study, 51 pregnant women admitted with PE and 55 normotensive healthy pregnant women matched for age and gestational age were compared. Information regarding clinical characteristics, neonatal findings, and placental properties such as syncytial knots, vascular structure density, placental area, volume, and weight) was retrieved.Results: Massive perivillous fibrinoid deposition, syncytial knots and decreased vessels in terminal villi were significantly frequent in the PE group compared to the controls. However, these histopathological findings were not associated with clinical and neonatal outcomes.Conclusions: Syncytial knot and perivillous fibrin deposition are significant microscopic findings of preeclampsia. However, the presence and amount of fibrin deposition were not correlated with perinatal outcome.

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Birth weight, Apgar score, and fetal complications in mothers with severe preeclampsia

Cited by 6 publications

References 14 publications

A New Predictor for Growth Restriction in Preeclampsia. A Case Control Study

A New Predictor for Growth Restriction in Preeclampsia. A Case Control Study

Neonatal Outcomes of Severe Preeclampsia in Neonates Under 34 Weeks of Gestation

Can Placental Histopathological Lesions Be a Guide to Maternal and Neonatal Outcomes in Patients With Preeclampsia?

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