Biotechnological approaches for cultivation and enhancement of secondary metabolites in Arnica montana L.

Petrova, Maria; Zayova, Ely; Vassilevska-Ivanova, R.; Vlahova, M.

doi:10.1007/s11738-012-0987-x

Cited by 14 publications

(15 citation statements)

References 53 publications

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“…Roots of A. montana contain thymol, which is used for flavouring purposes, as antioxidant in foodstuffs and beverages and also as fungicide, preservative and insecticidal agent . Roots of the plant are also used as bacteriostatic, antiphlogistic, choleretic and cholagogic due to presence of polyacetylenic compounds, phenol esters and phenolcarboxylic acids . Alcoholic or isopropanolic extract of A. montana flowers in the form of liquid formulations such as syrups, tinctures and ointments is used for the treatment of cattle, sheep, horses, swine and goats for inflammation of udder, joints, tendons, skin; eczema and to cure wounds of mucous membrane and skin .…”

Section: Occurrence Botanical Description and Ethnopharmacologymentioning

confidence: 99%

Arnica montana L. – a plant of healing: review

Kriplani

Guarve

Baghael

2017

Journal of Pharmacy and Pharmacology

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Objectives Arnica montana is a widely used therapeutic plant used traditionally to treat various ailments. The objective of this study was to evaluate the botany, phytochemistry and ethnopharmacology along with special emphasis given on pharmacological activity of plant A. montana. Key findings The plant extracts have been reported to possess antibacterial, antitumor, antioxidant, anti-inflammatory, antifungal and immunomodulatory activity. A wide range of chemical compounds including sesquiterpene lactones and their short-chain carbonic acid esters, flavonoids, carotenoids, essential oils, diterpenes, arnidiol, pyrrolizidine alkaloids, coumarins, phenolic acids, lignans and oligosaccharides, etc., are found in different parts of the plant. Summary It has been scrutinized that extensive research has been carried out to explore the therapeutic potential of flowers of the plant. Therefore, investigations should be carried out to explore the therapeutic potential of other parts of the plant for better therapeutic utilization.

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Section: Occurrence Botanical Description and Ethnopharmacologymentioning

confidence: 99%

Arnica montana L. – a plant of healing: review

Kriplani

Guarve

Baghael

2017

Journal of Pharmacy and Pharmacology

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“…Proizvodnja rasada iz semena i vegetativnim putem je bila prilično jednostavna i u velikoj meri uspešna, iako neki literaturni podaci ukazuju na probleme u imitiranju prirodnih uslova za razvoj klijanca (Kalynyak et al, 1995;Petrova et al, 2012). Iz prethodnih istraživanja plantažnog gajenja arnike primećeno je da biljke provode čitavu jednu vegetaciju u fazi rozete (Bomme et al, 1995;Galambosi, 1999;Radanovic et al, 2007), a da tek u narednoj vegetaciji razvijaju generativne organe.…”

Section: Stanje Ogleda I Broj Preživelih Biljakaunclassified

Influence of growing conditions on morphological and chemical properties and biological effects of extracts of Arnica montana L.

Pljevljakušić¹

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Belgrade, 2012(1,7 -2,4%).Mikroskopskim snimanjem samlevenog biljnog materijala pod različitim uveličanjima ustanovljena je jednostavna procedura identifikacije cveta arnike u odnosu na dva pretpostavljena falsifikata. Tako Since the A. montana plant specie is not native to the region of Serbia, although it occurs spontaneously in some mountain areas of neighboring countries and the Balkans in general, the aim of this study was to find a suitable technology solution of field cultivation based on the examination of induced various ecological factor effects.In this research, beside observations connected with flower heads, as the main drug, underground parts of arnica: rhizome and roots, were also studied as side products. The first phase of the experimental work included a three-year three-factorial field experiment in different modes of production, where as the factors examined: time of plantation establishment (spring and autumn planting), fertilization (manure and NPK) and methods of propagation (from seed and clonal propagation -division of the tuft). In the second phase of the experiment, characterization of the raw material was carried out in the terms of its rapid identification, qualitative evaluations based on the content of secondary metabolites and testing of biological effects of extracts obtained.Tests were performed on the field experiment conducted in 2008 at locality of Kaludjerske Bare (1008 m) on mountain Tara, in area of Nursery production department of the National Park "Tara". Since arnica its first vegetation remains in the rosette phenophase, all measurements of morphological parameters, yields and chemical Summary Doctoral Dissertation

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“…In this regard, adventitious and hairy roots are especially useful due to their fast growth and high yield of secondary metabolites (Gounaris 2010;Baque et al 2012). Nevertheless, essential oils are often found in substantial amounts also in shoot cultures, such as those of Arnica montana (Petrova et al 2012), Thymus caespititius (Mendes et al 2013) and Mentha sp. (Hilton et al 1995).…”

Section: Introductionmentioning

confidence: 99%

Production of essential oils from in vitro cultures of Caryopteris species and comparison of their concentrations with in vivo plants

et al. 2015

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The chemical composition of hydrodistilled essential oils obtained from aerial parts and roots of selected Caryopteris ('bluebeard') species (C. incana, C. mongolica, Caryopteris 9 clandonensis), as well as the newly established in vitro shoot and adventitious root cultures of the above plants, was analyzed by gas chromatography-mass spectrometry. Essential oil content and composition differed significantly depending on the type of plant material analyzed. Adventitious roots were characterized by the highest essential oil yield, reaching 1.8 % V/DW in Caryopteris 9 clandonensis. Limonene and cedrol were the main components of the essential oil derived from aerial parts of the intact plants (11.9-16.0 and 10.7-10.9 %, respectively), whereas the volatile fractions of the in vivo roots of all species contained large amounts of 3,5-bis(1,1-dimethyl)-phenol (12.9-26.2 %). 1,8-cineole, absent in the intact plant materials, was the dominating volatile constituent of the essential oils obtained from in vitro shoots (24.8-34.2 %). The volatile oil derived from adventitious root cultures consisted primarily of 1-octen-3-ol (19.7-31.5 %) and medicinally relevant diterpenoids: abietatriene and trans-totarol, which were accumulated in considerable quantities, especially in the adventitious roots of C. clandonensis (21.6 and 29.2 %, respectively).

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Biotechnological approaches for cultivation and enhancement of secondary metabolites in Arnica montana L.

Cited by 14 publications

References 53 publications

Arnica montana L. – a plant of healing: review

Arnica montana L. – a plant of healing: review

Influence of growing conditions on morphological and chemical properties and biological effects of extracts of Arnica montana L.

Production of essential oils from in vitro cultures of Caryopteris species and comparison of their concentrations with in vivo plants

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