Biomimetic fabrication of new bioceramics-introduced fibrous scaffolds: From physicochemical characteristics to in vitro biological properties

Liu, Tao; Chen, Yingrui; Lai, Dongzhi; Zhang, Lixiang; Pan, Xiaodan; Chen, Jianyong; Weng, Hequn

doi:10.1016/j.msec.2018.09.063

Cited by 13 publications

(3 citation statements)

References 41 publications

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“…The autologous bone transplantation has limited clinical application due to the re-injury to the patient, lack of graft materials, bone resorption and donor site complications. The allogeneic bone grafts can avoid these limitations, however, these pose a risk of cross-infection, long-term complications and immune response [2]. In the past few decades, the rapid development of the bone tissue engineering (BTE) provides new possibilities for the clinical treatment of the organs as well as tissue repair and reconstruction.…”

Section: Introductionmentioning

confidence: 99%

Retracted: Preparation and biological properties of silk fibroin/nano-hydroxyapatite/hyaluronic acid composite scaffold

et al. 2021

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In this study, the silk fibroin/nano-hydroxyapatite/hyaluronic acid (SF/nHAp/HA) composite scaffolds with different HA contents were developed by blending, cross-linking and freeze-drying, and their physicochemical properties and cell biocompatibility in vitro were subsequently studied. It was observed that the molecular conformation of the composite scaffolds was mainly composed of silk I and a small amount of the β-sheets structure. On enhancing the HA content, the pore size of the scaffold decreased, while the porosity, water absorption, swelling ratio and mechanical properties were observed to increase. In particular, the SF/nHAp/HA scaffold with a 5.0 wt% ratio exhibited the highest water absorption and mechanical properties among the developed materials. In addition, the in vitro cytocompatibility analysis showed that the bone marrow mesenchymal stem cells exhibited excellent cell proliferation and osteogenic differentiation ability on the SF/nHAp/5.0 wt%HA scaffolds, as compared with the other scaffolds. It can be concluded that the developed composite scaffolds represent a promising class of materials for the bone tissue repair and regeneration.

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Section: Introductionmentioning

confidence: 99%

Retracted: Preparation and biological properties of silk fibroin/nano-hydroxyapatite/hyaluronic acid composite scaffold

et al. 2021

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“…Compared with SF nanofibers, MGHA‐loaded SF nanofibers significantly enhanced the cell viability and osteogenic differentiation of human mesenchymal stem cells (hMSCs). [ 117 ] Bone tissue regeneration is coregulated by osteogenic and angiogenic growth factors, and bone regeneration can be promoted through time‐controlled release of these two growth factors. Cheng prepared core–shell nanofibers by coaxial electrospinning.…”

Section: Application Of Electrospun Silk Fibroin Nanofibers In Tissue...mentioning

confidence: 99%

“…Compared with SF nanofibers, MGHAloaded SF nanofibers significantly enhanced the cell viability and osteogenic differentiation of human mesenchymal stem cells (hMSCs). [117] Bone tissue regeneration is coregulated by Figure 3. A) Schematic illustration of two-step cross-electrospinning to manufacture a small-diameter vascular graft with an oriented intimal structure and a vertically porous outer layer.…”

Section: Bone Tissue Regenerationmentioning

confidence: 99%

Silk Fibroin Combined with Electrospinning as a Promising Strategy for Tissue Regeneration

Chen

et al. 2022

Macromolecular Bioscience

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The development of tissue engineering scaffolds is of great significance for the repair and regeneration of damaged tissues and organs. Silk fibroin (SF) is a natural protein polymer with good biocompatibility, biodegradability, excellent physical and mechanical properties and processability, making it an ideal universal tissue engineering scaffold material. Nanofibers prepared by electrospinning have attracted extensive attention in the field of tissue engineering due to their excellent mechanical properties, high specific surface area, and similar morphology as to extracellular matrix (ECM). The combination of silk fibroin and electrospinning is a promising strategy for the preparation of tissue engineering scaffolds. In this review, the research progress of electrospun silk fibroin nanofibers in the regeneration of skin, vascular, bone, neural, tendons, cardiac, periodontal, ocular and other tissues is discussed in detail.

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Microstructure, mechanical properties and in vitro biocompatibilities of a novel bionic hydroxyapatite bone scaffold prepared by the addition of boron nitride

et al. 2020

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Biomimetic fabrication of new bioceramics-introduced fibrous scaffolds: From physicochemical characteristics to in vitro biological properties

Cited by 13 publications

References 41 publications

Retracted: Preparation and biological properties of silk fibroin/nano-hydroxyapatite/hyaluronic acid composite scaffold

Retracted: Preparation and biological properties of silk fibroin/nano-hydroxyapatite/hyaluronic acid composite scaffold

Silk Fibroin Combined with Electrospinning as a Promising Strategy for Tissue Regeneration

Microstructure, mechanical properties and in vitro biocompatibilities of a novel bionic hydroxyapatite bone scaffold prepared by the addition of boron nitride

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