Biomedical Applications of &lt;em&gt;Chasmanthera dependens&lt;/em&gt; stem extract mediated silver nanoparticles as Antimicrobial, Antioxidant, Anticoagulant, thrombolytic, and Larvicidal agents

Aina, Daniel Ayandiran; Owolo, Oluwafayoke; Lateef, Agbaje; Aina, Folasade O.; Hakeem, Abbas Saeed; Adeoye-Isijola, Morenike O.; Okon, Victor; Asafa, T. B.; Elegbede, Joseph Adetunji; Olukanni, Olumide D.; Adediji, Isaac Oluwole

doi:10.33640/2405-609x.1018

Cited by 40 publications

(11 citation statements)

References 30 publications

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“…Over the past periods, silver has been proved to be a harmless inorganic antibacterial agent that is non-toxic and well recognized for the assassination of about 650 kinds of diseases producing microbes [15][16][17] . Silver has been labeled as energetic for its capability to exercise potential for a varied variety of biological applications such as anti-fungal agents, anti-bacterial agents, avoiding contagions, healing wounds, and anti-inflammatory even at low concentrations 18,19 . Silver ions are involved in the devising of dental resins, bone adhesive, ion exchange fibers, and medical tools coating 20 .…”

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confidence: 99%

Optimization for biogenic microbial synthesis of silver nanoparticles through response surface methodology, characterization, their antimicrobial, antioxidant, and catalytic potential

Ibrahim

Ahmad

Manzoor

et al. 2021

Sci Rep

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Silver is a poisonous but precious heavy metal that has widespread application in various biomedical and environmental divisions. Wide-ranging usage of the metal has twisted severe environmental apprehensions. Henceforth there is a cumulative call for the progress of modest, low-cost and, the ecological method for remediation of silver. In the present study, Bacillus cereus was isolated from contaminated soil. Various experimental factors like the amount of AgNO3, inoculum size, temperature, time, and pH were improved by using central composite design (CCD) grounded on response surface methodology (RSM). Optimized values for AgNO3 (1 mM) 10 ml, inoculum size (Bacillus cereus) 8.7 ml, temperature 48.5 °C, time 69 h, and pH 9 showed in the form of optimized ramps. The formed nanoparticles stayed characterized by UV–visible spectrophotometer, Scanning Electron Microscopy, Fourier transform infra-red spectrometry, particle size analyzer, and X-ray diffraction. The particle size ranges from 5 to 7.06 nm with spherical form. The antimicrobial effectiveness of synthesized nanoparticles was tested contrary to five multidrug resistant microbial strains, Staphylococcus epidermidis, Staphylococcus aureus, Escherichia coli, Salmonella enterica, Porteus mirabilis by disc diffusion method. The minimum inhibitory concentrations and minimum lethal concentrations were detected by the broth macro dilution method. 2,2-diphenyl-1-picrylhydrazyl-hydrate (DPPH) was used to check the free radical scavenging ability of biogenic silver nanoparticles. Similarly, anti-radical activity was checked by 2,2′-Azino-Bis-3-Ethylbenzothiazoline-6-Sulfonic Acid (ABTS) with varying time intervals. Catalytic potential of biosynthesized silver nanoparticles was also investigated.

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confidence: 99%

Optimization for biogenic microbial synthesis of silver nanoparticles through response surface methodology, characterization, their antimicrobial, antioxidant, and catalytic potential

Ibrahim

Ahmad

Manzoor

et al. 2021

Sci Rep

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“…Several authors have reported different colours for AgNPs solution which includes dark brown reported by Aina et al [44] and Lateef et al [45] using Chasmanthera dependens and Petiveria alliacea plant materials, respectively, while reddish brown colouration was reported for corn silk AgNPs [28]. Lateef et al [20] reported the formation of dark brown AgNPs solution using the crude extracellular keratinase of the strain of B. safensis LAU 13, Jeevan et al [46] reported the formation of yellowish-brown AgNPs using cultured supernatant of Pseudomonas aeruginosa, while Oladipo et al [22] reported dark brown AgNPs using cell free-extracts of Enterococcus species.…”

Section: Biosynthesis and Characterization Of Agnpsmentioning

confidence: 97%

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Akintayo

Yekeen

Azeez

et al. 2021

Nano Plus: Sci. Tech. Nanomat.

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“…Thus, the concentration of 5 mM would be ideal for the further optimization of pH factor. For this purpose, the extract and 5 mM silver nitrate solution were adjusted to different pH (7,9,12); with increasing the reaction pH, the absorbance band exhibited a peak at the area of 400 nm (Figure 2(d)). It seems that electrical charges of biomolecules were changed by reaction pH, and possible to influence their capping and stabilizing capacities and subsequently the synthesis and growth rate of NPs (54).…”

Section: Biosynthesis Of Snpsmentioning

confidence: 99%

Antimicrobial, antioxidant, anti-glycation and toxicity studies on silver nanoparticles synthesized using Rosa damascena flower extract

Peron

Hadi

Azarbani

et al. 2021

Green Chemistry Letters and Reviews

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The perspective of this research was to investigate the antioxidant, antibacterial, cytotoxic activity and anti-glycation of the SNPs synthesized by aqueous flower extract of pink Rosa damascena plant and compare with the biological effect of plant extract. The antioxidant activity of plant extract, and SNPs, their inhibitory effect on albumin glycosylation and also the cytotoxic effect on the human fibroblast cells were assessed by DPPH, spectrophotometric assay and MTT test, respectively. The antibacterial activity of SNPs against Staphylococcus aureus, Bacillus cereus, Escherichia coli and Klebsiella pneumoniae was examined by the disk diffusion method. The percentage of free radicals inhibited by the extract was increased compared to the SNPs. The flower extract and the SNPs both showed anti-glycation effects under in vitro conditions, but SNPs showed the efficient inhibitory effect of on glycation of BSA in the order; 1000 extract < 500 SNP < 250 SNP < 1000 SNP. The toxicity effects of the extract and SNPs were also found to depend on their concentration and time of incubation, still, SNPs showed 8% higher toxicity than the extract. Although SNPs showed antibacterial activity, their effect on S. aureus was significant. It is concluded that the SNPs exhibited multifunctional properties for many medicinal applications.

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Biomedical Applications of <em>Chasmanthera dependens</em> stem extract mediated silver nanoparticles as Antimicrobial, Antioxidant, Anticoagulant, thrombolytic, and Larvicidal agents

Cited by 40 publications

References 30 publications

Optimization for biogenic microbial synthesis of silver nanoparticles through response surface methodology, characterization, their antimicrobial, antioxidant, and catalytic potential

Optimization for biogenic microbial synthesis of silver nanoparticles through response surface methodology, characterization, their antimicrobial, antioxidant, and catalytic potential

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Antimicrobial, antioxidant, anti-glycation and toxicity studies on silver nanoparticles synthesized using Rosa damascena flower extract

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