2010
DOI: 10.1007/s11695-010-0147-6
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Biomechanical Properties of Skin in Massive Weight Loss Patients

Abstract: The skin of MWL patients demonstrated stronger mechanical parameters than that of cosmetic patients in the medial part of the abdomen; however, the decrease in elastic fibers associated with a decrease in newly formed collagen seemingly provides a contradiction. Skin changes with MWL merits further study to understand it more completely.

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Cited by 31 publications
(33 citation statements)
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“…The integumentary scarring process is complex and involves many contributing factors; scarring therapy is a scientific field that is still expanding [31], with many doubts as to the direction in which it should proceed. To understand how the integument of the morbidly ex-obese is different, studies of the epidermis, dermis [10][11][12][13]32], and hypodermis [10,33] have attempted to characterize the tissue as to guide the future testing of innovative therapies.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The integumentary scarring process is complex and involves many contributing factors; scarring therapy is a scientific field that is still expanding [31], with many doubts as to the direction in which it should proceed. To understand how the integument of the morbidly ex-obese is different, studies of the epidermis, dermis [10][11][12][13]32], and hypodermis [10,33] have attempted to characterize the tissue as to guide the future testing of innovative therapies.…”
Section: Discussionmentioning
confidence: 99%
“…The structure of integumentary connective tissue is highly mobile and macroscopically irregular; in the exobese individual [33], the dermal network of type I collagen and elastin is deformed [10,11,32], and there is a lower quantity of these two components of the extracellular matrix in the abdominal dermis, especially at the IU level [13], where the concentrations of heparan sulfate and type III collagen are reduced due to poor genetic expression of these elements in the tissue [12].…”
Section: Discussionmentioning
confidence: 99%
“…An inverse correlation between the Ua/Uf and sagging was described in obese individuals [24]. Stronger mechanical characteristics were found in samples of abdominal skin removed from massive weight loss patients [15]. Another study, in mice, reported a progressive reduction of Ua with weight gain and a reduction of the net elasticity when animals had previously been subjected to a high-fat diet [33].…”
Section: Discussionmentioning
confidence: 99%
“…Recently, obesity has been related with the elevated tissue loads which explain pressure ulcers and determine more complex deep tissue injuries [13]. New knowledge is needed to better understand the multiple controversies and contradictions involving biomechanical adaptation of skin in weight loss provided by cosmetic intervention (abdominoplastia) or other strategies and procedures evoking massive weight reduction [13,14,15]. …”
Section: Introductionmentioning
confidence: 99%
“…Hud som har vaert utspent over lengre tid, får nedsatt elastisitet (19), og det store vekttapet følges ofte av tilsvarende mengder overflødig hud. Mange fedmeopererte pasienter kan få så store fysiske plager at de vil ha behov for plastikkirurgiske korreksjoner (4,5,20).…”
Section: Overflødig Hud Etter Bariatrisk Kirurgiunclassified