Biologically synthesized titanium oxide nanostructures combined with morphogenetic protein as wound healing agent in the femoral fracture after surgery

Zhang, Yushu; Zhang, Chuanlian; Liu, Kemiao; Zhu, Xia; Liu, Fang; Ge, Xiaofen

doi:10.1016/j.jphotobiol.2018.03.005

Cited by 17 publications

(9 citation statements)

References 28 publications

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“…Synthetic methods of TiO 2 NPs generally include sol–gel synthesis, hydrothermal methods, microwave methods and green synthetic strategies [ 6 ]. Currently, green synthetic strategies using plant extracts have been actively applied to produce TiO 2 NPs: Aloe barbadensis [ 8 ], Citrus limon [ 9 ], Trigonella foenum-graecum [ 10 ], Cochlospermum gossypium [ 11 ], Eichhornia crassipes [ 12 ], Artemisia haussknechtii [ 13 ], Echinacea purpurea [ 14 ], Carica papaya [ 15 ], Syzygium cumini [ 16 ], and Citrus sinensis [ 17 ]. The diverse activity of the abovementioned TiO 2 NPs has been reported as follows.…”

Section: Introductionmentioning

confidence: 99%

“…Anatase TiO 2 NPs green-synthesized using Cochlospermum gossypium (Kondagogu gum) showed photocatalytic activity on organic dyes [ 11 ]. Interestingly, TiO 2 NPs produced by Eichhornia crassipes were combined with morphogenic proteins [ 12 ]. These newly prepared TiO 2 NPs demonstrated effective bone fusion behavior and enhanced antibacterial activity against pathogenic bacteria.…”

Section: Introductionmentioning

confidence: 99%

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Facile Green Synthesis of Titanium Dioxide Nanoparticles by Upcycling Mangosteen (Garcinia mangostana) Pericarp Extract

et al. 2022

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In the present report, green synthesis of titanium dioxide nanoparticles (TiO2 NPs) was performed by upcycling mangosteen (Garcinia mangostana) pericarp extract (methanol and ethyl acetate extracts). Field emission scanning electron microscopy images revealed an aggregated structure with a highly porous network of TiO2 NPs. TiO2 NPs synthesized with ethyl acetate extract (EtOAc-TiO2 NPs) exhibited more monodispersity and possessed smoother surfaces than the control TiO2 NPs (Con-TiO2 NPs) and TiO2 NPs synthesized with methanol extract (MeOH-TiO2 NPs). High-resolution X-ray diffraction patterns clearly confirmed that TiO2 NPs had a crystalline nature. A mixture of anatase and rutile was observed in Con-TiO2 NPs and MeOH-TiO2 NPs, while EtOAc-TiO2 NPs had only anatase with the smallest size (12.50 ± 1.81 nm). Ethyl acetate extract contained the highest amount of α-mangostin; thus, the surface of TiO2 NPs was functionalized with ethyl acetate extract. The functionalized TiO2 NPs synthesized with ethyl acetate extract (EtOAc-TiO2-αm) showed the highest 2,2-diphenyl-1-(2,4,6-trinitrophenyl)hydrazyl (DPPH) radical scavenging activity. In vitro cell viability on mouse fibroblast cells (NIH3T3) indicated that the newly synthesized TiO2 NPs did not show any significant cytotoxicity. Therefore, the TiO2 NPs in the present report have the potential to be used in cosmetic applications such as sunscreens.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Facile Green Synthesis of Titanium Dioxide Nanoparticles by Upcycling Mangosteen (Garcinia mangostana) Pericarp Extract

et al. 2022

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“…McFarland standard [13,47,48]. Separate suspensions of bacteria were injected onto the nutrient agar's surface.…”

Section: Investigation Of Agar Well Diffusion Methodsmentioning

confidence: 99%

Facile construction of antibiotics-loaded glucose-capped gold nanoparticles for in vitro antimicrobial and treatment and care of severe Pneumonia

Shi

Liu

2023

Mater. Res. Express

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From the perspective of gold nanoparticles (GNPs)' potential antibacterial applications, we demonstrate the fabrication, characterization, and effective antimicrobial activity of gentamicin (GM) and kanamycin (KAN) dynamically loaded to glucose-capped gold nanoparticles (g-GNPs). Infra-red (FT-IR) spectroscopy analyzed the synthesized GNPs and g-GNPs with encapsulated antibiotic drugs. Various spectroscopical methods characterized g-GNPs and drug-loaded nanoparticles. A minimum inhibitory concentration (MIC) and active curves in the Klebsiella pneumonia strain were used to evaluate the antibacterial activity of aminoglycoside-loaded g-GNPs, and the results showed that the nanoparticles had an appropriate antimicrobial effect on the clinical strain of the bacteria. There were bacteriostatic effects and an inhibiting effect on the growth of bacteria at doses of 33 to 65 µg/ml for each GM@g-GNPs and KAN@g-GNPs. With zones of Inhibition (ZOI) of 27 and 29 mm, g-GNPs-loaded antimicrobial medications demonstrated more antibacterial activity in well diffusion experiments than free nanomaterials and antimicrobial drugs, with ZOI of 21.00 and 10.00 mm, respectively. GM and KAN-loaded g-GNPs were examined using crystal violet assay for their antibiofilm activity. Findings suggested that the concentration of nanoparticles and anti-biofilm activity were directly linked. The cell membrane integrity was assessed in g-GNPs loaded with GM and KAN, and the results showed that nucleic acids and proteins released into the environment were significant. The inhibitory effects of GM@g-GNPs and KAN@g-GNPs on bacterial efflux pump (EP) was assessed, and the result displayed that all strains were sensitive to moderate concentration of NPs and highly sensitive to concentrations of 0.6 and 0.9 µg/ml of ethidium bromide (EtBr) and 64 to 128 µg/ml of GM@g-GNPs and KAN@g-GNPs. The findings demonstrate that all strains were responsive to moderate nanoparticle concentrations.

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“…Titanium-based coated electrode could be used in many aspects of coating electrode electrolysis, such as chlor-alkali technology, seawater electrolysis, and waste water purification [18]. In addition, the shape of titanium-based coated electrodes was very malleable, with common shapes such as plates, grids, rods and tubes [19,20]. Considering the high efficiency and convenience of the electrode plate, the titanium-based coating electrode was prepared by using the mesh titanium substrate in this experiment.…”

Section: Introductionmentioning

confidence: 99%

Decomposition of Organic Matter from Wastewater Using Ti/IrO<sub>2</sub>-RuO<sub>2</sub> Coated Electrodes: Electrode Characteristics and Removal Efficiency

Leng¹,

Niu²,

Zhou³

et al. 2022

Pol. J. Environ. Stud.

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In this study, the preparation characteristics of coated electrodes were used to remove organic matter from wastewater. The effects of low concentration range in different current densities and pH on the removal of organic substances, chemical oxygen demand (COD) and ammonia nitrogen (NH 3 -N) by the coated electrode were explored. The experimental results indicated that the removal efficiency of NH 3 -N and COD achieved the optimum value when the electric current density was 8-10 mA/cm 2 , the pH value was mild alkaline or neutral, and the electrolysis time was about 30 min. The preparation process of coated electrode and the mechanism of degradation of organic matter in wastewater were investigated. The coated electrode was analyzed by blending Energy Dispersive X-Ray (EDX) and Scanning Electron Microscope (SEM). The results indicated that the titanium-based ruthenium coated electrode was more suitable for practical application.

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Biologically synthesized titanium oxide nanostructures combined with morphogenetic protein as wound healing agent in the femoral fracture after surgery

Cited by 17 publications

References 28 publications

Facile Green Synthesis of Titanium Dioxide Nanoparticles by Upcycling Mangosteen (Garcinia mangostana) Pericarp Extract

Facile Green Synthesis of Titanium Dioxide Nanoparticles by Upcycling Mangosteen (Garcinia mangostana) Pericarp Extract

Facile construction of antibiotics-loaded glucose-capped gold nanoparticles for in vitro antimicrobial and treatment and care of severe Pneumonia

Decomposition of Organic Matter from Wastewater Using Ti/IrO<sub>2</sub>-RuO<sub>2</sub> Coated Electrodes: Electrode Characteristics and Removal Efficiency

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