Biological Monitoring of Exposure to Benzene in Petrol Pump Workers and Dry Cleaners.

Verma, Yeshvandra; Rana, S. V. S.

doi:10.2486/indhealth.39.330

Cited by 20 publications

(12 citation statements)

References 22 publications

(11 reference statements)

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“…Significant difference in the values of phenol between alcoholics and smokers was observed in comparison to nonalcoholics and nonsmokers. Similar results were recorded in our earlier study made in petrol pump workers 7) . The metabolism of chemicals may be modified by social habits 17) .…”

Section: Discussionsupporting

confidence: 81%

“…However, no such study has apparently been made in Indian cities. Verma and Rana (2001) while performing biological monitoring studies in petrol pump workers reported that gasoline is a potent source of Specific gravity of urine samples was determined by an urinometer (Atago Company Ltd. Tokyo, Japan). Creatinine was determined by alkaline picrate method 8) .…”

Section: Introductionmentioning

confidence: 99%

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Biological Monitoring of Exposure to Benzene in Traffic Policemen of North India.

2003

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Occupational health of traffic policemen employed at six major towns of north India was monitored during these investigations. Traffic controllers face the risk of exposure to benzene present in the ambient air as a component of fuel exhaust. Inhaled benzene is metabolized and excreted as phenol. Our observations on urinary phenol show much higher values than prescribed by ACGIH. Furthermore, social habits like alcohol consumption and cigarette smoke were found to modulate benzene metabolism. It was noticed that cigarette smoke synergizes the effect of benzene whereas antagonistic effects of alcohol were observed.

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Section: Discussionsupporting

confidence: 81%

Section: Introductionmentioning

confidence: 99%

Biological Monitoring of Exposure to Benzene in Traffic Policemen of North India.

2003

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“…Shops 2 and 3 (range 18.8-53.1 mg/m 3 ) were considerably more contaminated than the others, where levels of 0.4-2.1 mg/m 3 in personal sampling and 0.1-1.3 mg/m 3 in stationary sampling were found. BZ values found in shops 2 and 3 were very high, even if compared with exposure levels for professional categories commonly exposed to BZ such as employees of petroleum industries 35) , automobile mechanics 36) , petrol pump attendants [37][38][39] .…”

Section: Air Monitoringmentioning

confidence: 99%

Exposure to Organic Solvents among Handicraft Car Painters: A Pilot Study in Italy

Vitali¹,

Ensabella²,

Stella³

et al. 2006

Ind Health

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Car repair painters usually experience long-term exposure to many different solvents. In Italy, the greater part of car painting shops are "handicraft", i.e. 2-5 workers and small premises. Usually workers do not have specific duties, but everyone takes part in all different operations. Moreover, working time is not standardized but varies according to the workload, working methods tend to be traditional, and compliance to individual protection devices is poor. We have hence assessed, on a sample of 8 italian handicraft car painting shops, the exposure levels to solvents, implementing three classic exposure monitoring methods: environmental sampling with charcoal tubes, personal sampling with diffusive charcoal samplers, and urinary determination of unmetabolised solvents. A simple regression analysis was performed to evaluate relationships between the three series of data. The solvents analysed were toluene, ethylbenzene, 1, 2-dichloropropane, n-butylacetate, n-amylacetate, xylene isomers, ethylacetate, and benzene. Benzene was included due to several factors, among others its presence (1% v/v) in the italian unleaded gasoline. Benzene was found in all shops, at levels around or higher than the 8-h timeweighted average limit (8-h TLV-TWA). Other solvents were found in the different shops at various levels, 10 2 -10 1 times the 8-h TLV-TWA. Air concentrations of toluene, n-butylacetate, xylenes, and benzene were positively correlated with urinary levels of the parent compounds, while a negative correlation was found for ethylbenzene. The health implications of workers' exposure level was briefly discussed.

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“…KR is indicative of more extensive nuclear chromatin aggregation which leads to disintegration of the nucleus [23]. Binucleus formation is considered as indicator of cytotoxicity, while KR and KL are considered as indicators of apoptosis [21].…”

Section: Resultsmentioning

confidence: 99%

Micronuclei - As a Biomarker of Genotoxicity in Automobile Mechanics of Western Maharashtra

Patil

Kanitkar

2018

Asian J Pharm Clin Res

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Objective: The aim of this study was to assess the potential cytogenetic damage associated with occupational exposure to polycyclic aromatic hydrocarbons (PAHs) among automobile mechanics (AMs) using micronuclei (MNs) and other nuclear abnormalities (NAs) such as binucleate cell (BN), karyorrhexis (KR), and karyolysis (KL) as biomarkers of genotoxicity. Methods:The study was conducted on 60 AMs between age group of 20-40 years who were working in automobile garages for more than 1 year from western Maharashtra, and 60 healthy males with same socioeconomic status were chosen as controls. AMs were divided into three groups based on their duration of exposure, i.e. 1-5 years, 6-10 years, and more than 11 years. The exfoliated buccal cells were obtained and fixed with methanol for 10 min. Then, air-dried and stained it with Giemsa stain. Statistical analysis was done using unpaired t-test for two groups and one-way ANOVA for multiple groups of exposures. Results:The mean values of MN, BN, KR, and KL in AMs (8.20, 13.57, 16.70, and 22.10, respectively) are significantly increased as compared to controls (5.10, 8.82, 12.30, and 16.12, respectively). As the year of exposure increased, the mean values of MN and other NAs were significantly increased in AMs (p<0.05).Conclusion: MN and other NAs reflect genetic changes and events associated with carcinogenesis. Therefore, the results of this study indicate that AMs exposed to PAHs are under risk of significant cytogenetic damage. Therefore, it is important to provide and to create better awareness of occupational hazards among these workers to promote occupational safety.

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Biological Monitoring of Exposure to Benzene in Petrol Pump Workers and Dry Cleaners.

Cited by 20 publications

References 22 publications

Biological Monitoring of Exposure to Benzene in Traffic Policemen of North India.

Biological Monitoring of Exposure to Benzene in Traffic Policemen of North India.

Exposure to Organic Solvents among Handicraft Car Painters: A Pilot Study in Italy

Micronuclei - As a Biomarker of Genotoxicity in Automobile Mechanics of Western Maharashtra

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