Biogenetic Autonomy of Mitochondria and Its Limits

Mitochondrial Genes and Translation Products

“…Although there is abundant evidence that mitochondrial translation and/ or transcription are controlled by the nUcleocytoplasmic system of the cell (20,72), the reverse does not appear to hold true. Most of the cytoplasmic products, including those that are destined to be integrated into enzymes containing mitochondrially derived subunits, are synthesized at near normal levels even when mitochondrial synthesis is inhibited.…”

CHLOROPLAST RIBOSOME BIOGENESIS IN CHLAMYDOMONAS

“…Under permissive conditions, however, the protein-synthesizing systems of mitochondria of baker's yeast, Saccharomyces cerevisiae, a facultative anaerobe (cf. Mahler, 1973), and of the chloroplast of the green acetate flagellate, Chlamydomonas reinhardtii (Boynton et al, 1972Goodenough and Levine, 1971) appear to be dispensable. In addition, variegated plastome mutants of barley, cotton, and Pelargonium have been described in which the white sectors show a deficiency of chloroplast ribosomes while green sectors are normal and apparently serve to support growth of the chloroplast ribosome-deficient tissue (BiSrner et al, 1973;Hagemann et al, 1973;Katterman and Endrizzi, 1973).…”

Association Between Subcellular Proliferating Membranes and Mitochondria in Dog Thyroid Follicular Cells Induced by Synthetic Double-Stranded Rna Administration

“…framework for these enzymes to be assembled. Indeed, recent studies have pro¬ vided conclusive evidence for self-assembly of subcellular structures (Mahler 1973). This growth of the GMM would tend to continue until a fusion with itself is accomplished (Fig.…”