Bioelectrical Impedance Analysis–Derived Measurements in Chronic Hepatitis C: Clinical Relevance of Fat‐Free Mass and Phase Angle Evaluation

Bering, Tatiana; Diniz, K.G.D.; Coelho, M.P.P.; Souza, Ana Carolina M. de; Melo, Luisa Freitas de; Vieira, Diego Alves; Soares, Maria Marta Sarquis; Kakehasi, Adriana Maria; Correia, Maria Isabel Toulson Davidson; Teixeira, Rosângela; Queiroz, Dulciene Maria Magalhães; Rocha, Gifone A.; Silva, Luciana D.

doi:10.1177/0884533617728487

Cited by 23 publications

(12 citation statements)

References 36 publications

(91 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In addition, PhA values might be altered in subjects with severe obesity due not only to changes in BCM but also to those in tissue hydration, which occur because of a physiologically higher ECW/TBW ratio in adipose tissue or a pathophysiological fluid overload [18]. Of note, in terms of body function PhA has been directly related to muscle strength [15,19], being higher in athletes [20] and lower in sarcopenic subjects [21], to impaired quality of life [22] and poor prognosis in various chronic diseases [23,24]. Thus, based on the aforementioned points, the EWGSOP 2019 consensus on sarcopenia proposed PhA as a possible index of muscle quality [9].…”

Section: Introductionmentioning

confidence: 99%

Bioelectrical impedance (BIA)-derived phase angle in adults with obesity: A systematic review

Vincenzo

Marra²,

Sacco

et al. 2021

Clinical Nutrition

View full text Add to dashboard Cite

Background & aims: Bioimpedance analysis-derived phase angle (PhA), as marker of body cell mass and cell integrity, might be altered in obesity, a condition which is characterized by alterations in muscle structure and function. The aim of this systematic review was to evaluate whether and to which extent PhA varies in individuals/ patients with excess body weight focusing on: a) changes in PhA due to obesity; b) changes in PhA after bariatric interventions or training programs. Methods: According to PRISMA criteria, a systematic literature search until February 2021 using PubMed, Embase, Scopus, and Web of Science was performed. Selection criteria included studies on patients with obesity without comorbidities other than metabolic diseases. Results: A total of 278 articles were first identified. After removing duplicates and excluding studies that did not fulfil the inclusion criteria, the full text of the remaining 80 potentially relevant studies was examined to finally retrieve 11 cross-sectional and 10 longitudinal studies. Few studies have shown that PhA is lower in individuals/patients with obesity than in controls. The only study on the matter showed a decrease with age after the fourth decade of life. Four out of five studies reported consistently greater mean values in men than in women. In two studies PhA was lower in patients with severe obesity; in addition, Patients with low PhA had higher BMI and PhA was inversely correlated with fat mass. Longitudinal studies showed that PhA markedly decreased after bariatric surgery and slightly increased after training programs. Conclusions: Thus, a relatively low number of studies have evaluated PhA in individuals/patients with obesity with sometimes contradictory and preliminary results. PhA might be useful to evaluate muscle quality in individuals/patients with obesity but further studies are needed to more accurately associate this variable with changes in muscle structure and strength, as well as in metabolic functions.

show abstract

Section: Introductionmentioning

confidence: 99%

Bioelectrical impedance (BIA)-derived phase angle in adults with obesity: A systematic review

Vincenzo

Marra²,

Sacco

et al. 2021

Clinical Nutrition

View full text Add to dashboard Cite

show abstract

“…The authors showed a statistically significant difference of a lower PA in patients with cirrhosis. This low PA was linked to malnutrition (23) . Dorna et al also demonstrated the association between PA and advanced fibrosis in HCV patients.…”

Section: Discussionmentioning

confidence: 99%

Malnutrition in Cirrhosis: Association With Etiology and Hepatocellular Dysfunction

Oliveira

Fernandes

et al. 2020

Arq. Gastroenterol.

View full text Add to dashboard Cite

BACKGROUND: The protein-energy malnutrition alters the prognosis of patients with cirrhosis. Its prevalence may vary according to the etiology of liver disease, it´s severity and the evaluation of the method applied. The infection by the hepatitis C virus (HCV) and alcoholism are the main etiologies of cirrhosis and result in a significant morbidity and mortality. OBJECTIVE: To evaluate the nutritional status of patients with cirrhosis according the liver disease etiology and severity. METHODS: It is a prospective study, in which the sample was for convenience and consisted of patients with cirrhosis, infected by HCV or alcoholic etiology. The nutritional status evaluation was carried out through anthropometry, food consumption, bioelectrical impedance (BIA) and subjective global assessment (SGA). The anthropometric data evaluated were weight, height, body mass index (BMI), triceps skinfold (TSF), circumference of the arm (CA), non-dominant handshake strength (FAM) and the adductor pollicis muscle thickness (APM). Patients were classified according to the severity of liver disease, using the Child-Pugh and Model for End-stage Liver Diseases (MELD) scores. RESULTS: Ninety patients with cirrhosis were evaluated, 47 with HCV and 43 with alcoholic etiology. The prevalence of protein-calorie malnutrition ranged from 10.9% to 54.3% in the HCV group and from 4.7% to 20.9% in the alcoholic group, depending on the method used for evaluation. The group with HCV infection presented a higher malnutrition prevalence in comparison to the alcoholic in the following evaluations: TSF (P<0.001), phase angle (PA) (P=0.016) and SGA (P=0.010). PA values were lower in patients with viral cirrhosis (5.68±1.05) when compared to those with alcoholic etiology (6.61±2.31) (P=0.016). When all patients were analyzed, regardless of etiology, an inversely correlation was observed among Child-Pugh score and PA values (P=0.018). CONCLUSION: HCV cirrhosis showed worse nutritional parameters in comparison to alcoholic etiology; however, the PA was associated with worse liver function in both etiologies.

show abstract

“…In 2018, Bering et al examined 135 patients (68 men and 67 women) with hepatitis C. They studied the nutritional status of patients using the Subjective Global Assessment (SGA) scale for the risk of developing cirrhosis. A low PA value was associated with high risk of developing liver cirrhosis (OR = 3.92, p < 0.01) and high risk of malnutrition (OR = 5.52, p = 0.05) [35].…”

Section: Discussionmentioning

confidence: 99%

Electrical Changes in Polish Patients with Chronic Heart Failure: Preliminary Observations

et al. 2019

View full text Add to dashboard Cite

Introduction: Direct parameters resistance (R), reactance (Xc), phase angle (PA), capacitance of membrane (Cm), and impedance ratio (Z200/Z5)) determined by bioelectrical impedance analysis (BIA) detect changes in tissue electrical properties and have been found to be a marker of cell membrane function in various diseases. Materials and Method: The cross-sectional study was conducted to investigate whether direct bioimpedance parameters differ in a group of heart failure (HF) patients divided on the basis of the New York Heart Association (NYHA) functional classes I–II and III–IV. BIA was evaluated in 100 patients with HF treated in Clinic of Cardiology and Internal Medicine, Department of Cardiology, Military Hospital, Lublin. Results: In men, lower PA values (p = 0.01), Xc (p < 0.01), Cm (p = 0.02), and higher values of the Z200/Z5 ratio (p < 0.01) were observed in patients classified into NYHA groups III and IV in comparison to those with lower stages of disease. Similar correlations were noted in women (only Cm differences were insignificant). In addition, in men, C-Reactive Protein (CRP) correlated negatively with PA (p < 0.01), Xc (p < 0.01), and Cm (p < 0.01) and positively with the Z200/Z5 index (p < 0.01). There were no similar correlations observed in women. Conclusion: Patients with advanced CHF have altered electrical values. Changes in electrical values may directly reflect tissues as well as the whole-body condition.

show abstract

Bioelectrical Impedance Analysis–Derived Measurements in Chronic Hepatitis C: Clinical Relevance of Fat‐Free Mass and Phase Angle Evaluation

Cited by 23 publications

References 36 publications

Bioelectrical impedance (BIA)-derived phase angle in adults with obesity: A systematic review

Bioelectrical impedance (BIA)-derived phase angle in adults with obesity: A systematic review

Malnutrition in Cirrhosis: Association With Etiology and Hepatocellular Dysfunction

Electrical Changes in Polish Patients with Chronic Heart Failure: Preliminary Observations

Contact Info

Product

Resources

About