Biodiversity characteristics of Teucrium polium species in Saudi Arabia

Bukhari, Najat A.; Al-Otaibi, Reem A.; Ibhrahim, Mohammed M.

doi:10.1016/j.sjbs.2014.11.002

Cited by 17 publications

(9 citation statements)

References 29 publications

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“…The genus Teucrium includes more than 100 species and is largely distributed in Europe, North Africa, Asia, and especially in the Mediterranean region [4,5]. The Saudi Arabia flora comprises six Teucrium species: T. hijazicum Hedge & R.A. King, T. leucocladum Boiss, T. oliverianum Ging.…”

Section: Introductionmentioning

confidence: 99%

HR-LCMS-Based Metabolite Profiling, Antioxidant, and Anticancer Properties of Teucrium polium L. Methanolic Extract: Computational and In Vitro Study

et al. 2020

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In this study, we investigate the phytochemical profile, anticancer, and antioxidant activities of Teucrium polium methanolic extract using both in vitro and in silico approaches. The results showed the identification of 29 phytochemical compounds belonging to 13 classes of compounds and 20 tripeptides using High Resolution-Liquid Chromatography Mass Spectrometry (HR-LCMS). 13R-hydroxy-9E,11Z octadecadienoic acid, dihydrosamidin, valtratum, and cepharantine were the main compounds identified. The tested extract showed promising antioxidant activities (ABTS-IC50 = 0.042 mg/mL; 1,1-diphenyl-2-picrylhydrazyl (DPPH)-IC50 = 0.087 mg/mL, β-carotene-IC50 = 0.101 mg/mL and FRAP-IC50 = 0.292 mg/mL). Using both malignant Walker 256/B and MatLyLu cell lines, T. polium methanolic extract showed a dose/time-dependent antitumor activity. The molecular docking approach revealed that most of the identified molecules were specifically binding with human peroxiredoxin 5, human androgen, and human progesterone receptors with high binding affinity scores. The obtained results confirmed that T. polium is a rich source of bioactive molecules with antioxidant and antitumor potential.

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Section: Introductionmentioning

confidence: 99%

HR-LCMS-Based Metabolite Profiling, Antioxidant, and Anticancer Properties of Teucrium polium L. Methanolic Extract: Computational and In Vitro Study

et al. 2020

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“…In Saudi Arabian folk medicine, germander ( T. polium ) is known under the vernacular name of “Jaada” used by Bedouins as a febrifuge and vermifuge to fight stomach and intestinal troubles. The plant is also used in cold and fever [ 24 , 25 , 26 ]. In the Mediterranean basin, many scientific reports highlighted the medicinal benefits of germander [ 27 , 28 , 29 , 30 ].…”

Section: Introductionmentioning

confidence: 99%

“…In the Mediterranean basin, many scientific reports highlighted the medicinal benefits of germander [ 27 , 28 , 29 , 30 ]. Few studies have focused on the chemical oil of T. polium in Middle East [ 26 , 31 ]. Most of the research on T. polium tends towards the uses of the plant and plant- based extract as antimicrobial compounds.…”

Section: Introductionmentioning

confidence: 99%

Phytochemical Screening, Antibacterial, Antifungal, Antiviral, Cytotoxic, and Anti-Quorum-Sensing Properties of Teucrium polium L. Aerial Parts Methanolic Extract

Alreshidi

Noumi

Bouslama

et al. 2020

Plants

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The chemical profile of Teucrium polium L. (T. polium) methanolic extract was tested using liquid chromatography coupled with high resolution mass spectrometry (HR-LCMS). Disc diffusion and microdilution assays were used for the antimicrobial activities. Coxsackievirus B-3 (CVB3) and Herpes simplex virus type 2 (HSV-2) were used for the antiviral activities. Chromobacterium violaceum (ATCC 12472 and CV026) and Pseudomonas aeruginosa PAO1 were used as starter strains for the anti-quorum sensing tests. Isoprenoids are the main class of compounds identified, and 13R-hydroxy-9E,11Z-octadecadienoic acid, valtratum, rhoifolin, sericetin diacetate, and dihydrosamidin were the dominant phytoconstituents. The highest mean diameter of growth inhibition zone was recorded for Acinetobacter baumannii (19.33 ± 1.15 mm). The minimal inhibitory concentrations were ranging from 6.25 to 25 mg/mL for bacterial strains, and from 6.25 to 25 mg/mL for Candida species. The 50% cytotoxic concentration on VERO (African Green Monkey Kidney) cell lines was estimated at 209 µg/mL. No antiviral activity was recorded. Additionally, T. polium extract was able to inhibit P. aeruginosa PAO1 motility in a concentration-dependent manner. However, the tested extract was able to inhibit 23.66% of the swarming and 35.25% of swimming capacities of PAO1 at 100 µg/mL. These results highlighted the role of germander as a potent antimicrobial agent that can interfere with the virulence factors controlled by the quorum-sensing systems.

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“…The taxonomic complexity of Teucrium is reflected in the changes in its classification using different characteristics as pollen morphology (Díez et al, 1993), karyology (Valdés-Bermejo and Sánchez-Crespo, 1978), indumentum characteristics (Manzanares et al, 1983;El Oualidi and Puech, 1993;Navarro and EL Oualidi, 2000b), phytochemistry (Harborne et al, 1986;VelascoNegueruela and Pérez-Alonso, 1990;Bukhari et al, 2014) and amino acid composition (Juani et al, 2004). Meanwhile, there is an imminent danger for genetic erosion of Libyan wild species due to the increment in drought and anthropogenic activities, that has resulted in habitat loss and fragmentation leading to the diminishing of the germplasm reservoir (Al-Idrissi et al, 1996).…”

Section: Resultsmentioning

confidence: 99%

Pollen morphology of <i>Teucrium</i> L. (Lamiaceae, Ajugoideae) in Libya

Marzouk

El-Darier

Askar

2017

Bangladesh J. Plant Taxon

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Pollen grains of 11 taxa of Teucrium from Libya were examined using light microscopy (LM) and scanning electron microscopy (SEM) in order to provide better insight on the evaluation of palynological attributes for species characterization of Teucrium with special emphasis on the five Libyan endemic. Two main pollen shapes were documented; subprolate and prolate or perprolate in T. fruticans. The exine sculpture inspected at surface, operculum and pole were mostly verrucate, perforate or scabrate. Teucrium fruticans attained the phenomenon of pollen dimorphism with two distinct shapes and specifics sculpture for each form. The results validated the taxonomic significance of pollen grains for the discrimination among Teucrium species in Libya.

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Biodiversity characteristics of Teucrium polium species in Saudi Arabia

Cited by 17 publications

References 29 publications

HR-LCMS-Based Metabolite Profiling, Antioxidant, and Anticancer Properties of Teucrium polium L. Methanolic Extract: Computational and In Vitro Study

HR-LCMS-Based Metabolite Profiling, Antioxidant, and Anticancer Properties of Teucrium polium L. Methanolic Extract: Computational and In Vitro Study

Phytochemical Screening, Antibacterial, Antifungal, Antiviral, Cytotoxic, and Anti-Quorum-Sensing Properties of Teucrium polium L. Aerial Parts Methanolic Extract

Pollen morphology of <i>Teucrium</i> L. (Lamiaceae, Ajugoideae) in Libya

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