Biochemical study on the potential therapeutic use of novel curcumin copper oxide nanocomposite in diabetic complications in rats

AlSenosy, Yakout; Prince, Abd El-Bary M.; Zaher, Amira

doi:10.21608/bvmj.2018.29427

Cited by 2 publications

(2 citation statements)

References 16 publications

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“…In 2018, Senosy et al have produced curcumin-CuO complex, where commercial CuO and curcumin were mixed and ground together. The formed NPs were reported for biomedical applications, where it was found curcumin-CuO nanocomplex has emerged an anti-diabetic effect in vivo on streptozotocin (STZ) diabetic mice (91).…”

Section: Synthesis Of Curcumin Conjugated Copper Oxide Nanoparticlesmentioning

confidence: 99%

Curcumin as a novel reducing and stabilizing agent for the green synthesis of metallic nanoparticles

Patra

Kurdi

2021

Green Chemistry Letters and Reviews

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This review expands for the first time the development of curcumin as reducing and stabilizing agent. Curcumin is widely used in food industries, cosmetic domain and the biomedical field. The combination of green synthesis and curcumin to produce nanoparticles has been effective as the amount of toxic waste is highly reduced. Starting with a general introduction about nanoparticles synthesis and curcumin, the use of curcumin as a principal reducing agent and stabilizing compounds in the production of nanoparticles is developed. Consecutively, the preparation of different nanoparticles as gold nanoparticles (Au NPs), silver nanoparticles (Ag NPs), copper nanoparticles (Cu NPs), iron nanoparticles (Fe NPs), and manganese and manganese oxide nanoparticles (Mn NPs, MnO NPs) using curcumin is investigated and elaborated. The mechanism of interaction of curcumin with the different metal has also been developed. A concluding section summarizes the advantages of using curcumin as reducing/ stabilizing agent in nanoparticles formation and their analytical applications.

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Section: Synthesis Of Curcumin Conjugated Copper Oxide Nanoparticlesmentioning

confidence: 99%

Curcumin as a novel reducing and stabilizing agent for the green synthesis of metallic nanoparticles

Patra

Kurdi

2021

Green Chemistry Letters and Reviews

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“…The developed nanocomplex has been tested for its anti-diabetic effect in vivo on streptozotocin (STZ) induced diabetic mice. Curcumin–CuO treatment resulted in a significant decrease in malonaldehyde (MDA) levels, increase in GSH and SOD levels, increase in insulin concentration, and upregulated mRNA-expression levels of insulin gene (IR-A and IR2), compared to the results of pure curcumin treatment [ 58 ]. Bhandari et al [ 59 ] reported a direct coating of Fe 3 O 4 NPs with curcumin and tested the antioxidant property of the composite.…”

Section: Metal Oxides As Curcumin Carriersmentioning

confidence: 99%

Curcumin Nanoformulations with Metal Oxide Nanomaterials for Biomedical Applications

et al. 2021

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In the past few decades, curcumin, a natural polyphenolic phytochemical, has been studied for treating a wide variety of diseases. It has shown promising results as a potential curative agent for a variety of diseases. However, its inherent limitations, such as poor aqueous solubility, poor absorbability, fast metabolic rate, and quick elimination from the body, have limited its application beyond preclinical studies. A huge number of studies have been made to address the issues of curcumin and to maximally utilize its potentials. Many review articles have tried to assess and summarize different nanocarriers, especially organic nanocarriers, for nanoformulations with curcumin. Nevertheless, few exclusive reviews on the progress in nanoformulation of curcumin with inorganic nanomaterials have been made. In this review, we present an exclusive summary of the progress in nanoformulation of curcumin with metal oxide nanoparticles. The beneficial feature of the metal oxide nanoparticles used in the curcumin nanoformulation, the different approaches followed in formulating curcumin with the metal oxides, and the corresponding results, protective effect of curcumin from different metal oxide caused toxicities, and concluding remarks are presented in the review.

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Biochemical study on the potential therapeutic use of novel curcumin copper oxide nanocomposite in diabetic complications in rats

Cited by 2 publications

References 16 publications

Curcumin as a novel reducing and stabilizing agent for the green synthesis of metallic nanoparticles

Curcumin as a novel reducing and stabilizing agent for the green synthesis of metallic nanoparticles

Curcumin Nanoformulations with Metal Oxide Nanomaterials for Biomedical Applications

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