Biochemical Effects of Some Traditional Nigerian Diets in Experimental Diabetic Rat Models

Ani, I. F.

doi:10.9734/ijbcrr/2012/1199

Cited by 4 publications

(1 citation statement)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The findings demonstrate the significance of eating mixed meals because the GI is much lower in mixed meals than it is in single servings of carbohydrate‐rich foods (Mbanya et al., 2003 ). Garri and afang soup, pounded yam, and edikang ekong soup consumption significantly lowered fasting blood glucose levels (Ani et al., 2011 ).…”

Section: African Diet and Management Of Diabetesmentioning

confidence: 99%

Functional foods of sub‐Saharan Africa and their implications in the management of type 2 diabetes: A review

Matsinkou Soh,

Ngaha Damndja,

Njintang Yanou

2023

Food Science & Nutrition

View full text Add to dashboard Cite

Throughout the world, the prevalence of metabolic diseases in general and type 2 diabetes (T2DM) in particular is constantly growing, and sub‐Saharan Africa (SSA) is not spared. The use of functional foods is a more practical option among the different approaches used in the management of T2DM owing to the fact that they are relatively less costly, safer, and more accessible. In addition to their low glycemic index just like foods currently used to manage diabetes, functional foods contain bioactive compounds such as polyphenols, dietary fibers, saponins, and peptides. They are so named because they have additional health advantages beyond their basic nutritional worth. Bioactive compounds can be found in a variety of SSA plant‐based foods, such as spices, fruits, vegetables, legumes, starchy foods, prepared foods, mixed foods, and prepared dishes. The goal of this review is to highlight some of the investigations into the effectiveness of local food and their antidiabetic mechanisms that have been studied in various SSA regions. Using the literature review as a basis, the authors state that SSA foods are rich in various bioactive compounds capable of regulating blood sugar through enhanced glucose tolerance, antioxidant effects, insulin sensitivity, and inhibition or activation of some key enzymes of the glucose metabolism that are linked to the prevention and management of T2DM. Many of the cited findings are preliminary, obtained from cell and preclinical studies, and therefore other studies need to be done to demonstrate the full potential of these foods to serve as bases for dietary guidelines.

show abstract

Section: African Diet and Management Of Diabetesmentioning

confidence: 99%

Functional foods of sub‐Saharan Africa and their implications in the management of type 2 diabetes: A review

Matsinkou Soh,

Ngaha Damndja,

Njintang Yanou

2023

Food Science & Nutrition

View full text Add to dashboard Cite

show abstract

Antihyperglycemic and antidyslipidemic activity of Musa paradisiaca‐based diet in alloxan‐induced diabetic rats

Ajiboye

Oloyede

Salawu

2017

Food Science & Nutrition

View full text Add to dashboard Cite

This study was aimed at investigating the antihyperglycemic and antidyslipidemic activity of Musa paradisiaca‐based diets in alloxan‐induced diabetic mellitus rats. Diabetes was induced by a single intraperitoneal injection of alloxan (150 mg/kg b.w) in 48 randomly selected rats. The rats were randomly grouped into four as follows: normal rats fed Dioscorea rotundata‐based diet, diabetic control rats fed D. rotundata‐based diet, diabetic rats fed D. rotundata‐based diet and administered metformin (14.2 mg/kg body weight) orally per day, and diabetic rats fed M. paradisiaca‐based diet. Body weight and fasting blood glucose level were monitored, on 28th days the rats were sacrificed, liver was excised. Thereafter, the hyperglycemic and dyslipidemic statii of the induced diabetic animals were determined. The M. paradisiaca‐based diet significantly (p < .05) reversed the levels of fasting blood glucose, with significant (p < .05) increase in insulin and glycogen concentrations. The diet also increased the activity of hexokinase with significant reduction (p < .05) in glucose‐6‐phosphatase and fructose‐1‐6‐diphosphatase activities. M. paradisiaca‐based diet demonstrated significant reduction (p < .05) in cholesterol, triacylglycerol (TG), very low‐density lipoprotein (VLDL), low‐density lipoprotein (LDL), and significant increase (p < .05) in high‐density lipoprotein (HDL) compared with those of diabetic control group. Also, M. paradisiaca‐based diet significantly (p < .05) reversed the activities of aspartate aminotransferase and alanine aminotransferase when compared with diabetic control animals. The consumption of this diet may be useful in ameliorating hyperglycemia and dyslipidemia in diabetes mellitus patients.

show abstract

Effect of cyanide ions (CN-) extracted from cassava (Manihotesculenta Crantz) on Alveolar Epithelial Cells (A549 cells)

et al. 2021

View full text Add to dashboard Cite

Biochemical Effects of Some Traditional Nigerian Diets in Experimental Diabetic Rat Models

Cited by 4 publications

References 13 publications

Functional foods of sub‐Saharan Africa and their implications in the management of type 2 diabetes: A review

Functional foods of sub‐Saharan Africa and their implications in the management of type 2 diabetes: A review

Antihyperglycemic and antidyslipidemic activity of Musa paradisiaca‐based diet in alloxan‐induced diabetic rats

Effect of cyanide ions (CN-) extracted from cassava (Manihotesculenta Crantz) on Alveolar Epithelial Cells (A549 cells)

Contact Info

Product

Resources

About