Biochemical changes following electro-acupuncture and static magnetic field therapy in rabbits for bone defect healing

Abstract

Aim: To evaluate the effect of Electro-Acupuncture (EA) and Static Magnetic Field (SMF) therapy on healing of bone defect in rabbits. Materials and MethodsA 2 mm bone defect was created at radial midshaft of 18 New Zealand White rabbits. The animals were then randomly divided into 3 equal groups. The animals in the group A did not receive any physiotherapy and served as control. Group B animals were treated with the EA using 50 Hz and 3-10 mA DD current for 10 min. Group C animals were treated with SMF therapy on alternate days till day 15. Activity of serum calcium (Ca), potassium (P) and ALP; Plasma Cortisol and LPO were evaluated preoperatively and on days 7, 15, 30 and 60 of experiment.Results: Postoperatively, SMF therapy treated animals exhibited higher Ca, P and ALP level and low initial level of Cortisol and LPO as compared to EA and control group animal. Conclusion:SMF and EA had positive effect on bone defect healing and early resolution of stress, induced due to creation of bone defect, however SMF had an edge over EA.