Biochemical and histological studies on adverse effects of mobile phone radiation on rat’s brain

Hussein, Shaymaa; El-Saba, A. A.; Galal, Mona K.

doi:10.1016/j.jchemneu.2016.07.009

Cited by 34 publications

(22 citation statements)

References 30 publications

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“…The brain is known as the most sensitive organ to oxidative stress because of its high oxygen consumption and low antioxidant content [ 40 ]. The results are in agreement with a recent study reporting that oxidative stress causes congestion and cerebral hemorrhage [ 41 ].…”

Section: Discussionsupporting

confidence: 93%

The Antioxidant Content and Protective Effect of Argan Oil and Syzygium aromaticum Essential Oil in Hydrogen Peroxide-Induced Biochemical and Histological Changes

Bakour

Soulo

Hammas

et al. 2018

IJMS

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Oxidative stress is an important etiology of chronic diseases and many studies have shown that natural products might alleviate oxidative stress-induced pathogenesis. The study aims to evaluate the effect of Argan oil and Syzygium aromaticum essential oil on hydrogen peroxide (H2O2)-induced liver, brain and kidney tissue toxicity as well as biochemical changes in wistar rats. The antioxidant content of Argan oil and Syzygium aromaticum essential oil was studied with the use of gas chromatography. The animals received daily by gavage, for 21 days, either distilled water, Syzygium aromaticum essential oil, Argan oil, H2O2 alone, H2O2 and Syzygium aromaticum essential oil, or H2O2 and Argan oil. Blood samples were withdrawn on day 21 for the biochemical blood tests, and the kidney, liver and brain tissue samples were prepared for histopathology examination. The results showed that the content of antioxidant compounds in Syzygium aromaticum essential oil is higher than that found in Argan oil. H2O2 increased level of blood urea, liver enzymes, total cholesterol, Low Density Lipoprotein (LDL-C), Triglycerides (TG) and Very Low Density Lipoprotein (VLDL), and decreased the total protein, albumin and High Density Lipoprotein-cholesterol (HDL-C). There was no significant effect on blood electrolyte or serum creatinine. The histopathology examination demonstrated that H2O2 induces dilatation in the central vein, inflammation and binucleation in the liver, congestion and hemorrhage in the brain, and congestion in the kidney. The H2O2-induced histopathological and biochemical changes have been significantly alleviated by Syzygium aromaticum essential oil or Argan oil. It is concluded that the Argan oil and especially the mixture of Argan oil with Syzygium aromaticum essential oil can reduce the oxidative damage caused by H2O2, and this will pave the way to investigate the protective effects of these natural substances in the diseases attributed to the high oxidative stress.

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Section: Discussionsupporting

confidence: 93%

The Antioxidant Content and Protective Effect of Argan Oil and Syzygium aromaticum Essential Oil in Hydrogen Peroxide-Induced Biochemical and Histological Changes

Bakour

Soulo

Hammas

et al. 2018

IJMS

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“…Adapun efek negatif tersebut berupa peningkatan aktivitas enzim NADH oksidase. Karena perubahan tersebut nantinya akan menimbulkan stres oksidatif pada hipokampus yang dapat merubah struktur organ itu sendiri serta mengakibatkan gangguan fungsi ataupun kerusakan sel pada hipokampus (Hussein et al, 2016). Dalam penelitian Hussein et al (2016), terdapat perubahan pada otak tikus pada saat diberi paparan radiasi ponsel selama 2 jam/hari selama 3 bulan.…”

Section: Pendahuluanunclassified

“…Apabila ditemukan perubahan degeneratif sel piramidal hipokampus pada subjek penelitian (bisa berupa tikus putih) yang dipaparkan gelombang elektromagnetik telepon seluler berarti terjadi kerusakan sel pada hipokampus karena proses stres oksidatif. Perubahan degeneratif ini dapat ditandai dengan perubahan bentuk sel piramidal yang awalnya berbentuk segitiga (triangular shape) menjadi bentuk yang tidak beraturan ataupun bentuk lain, adanya pengurangan ukuran diameter serta jumlah sel piramidal hipokampus (Hussein et al, 2016). Selain itu, perubahan sel piramidal hipokampus dapat ditandai dengan terjadinya degenerasi hidrofik ataupun piknosis pada inti sel.…”

Section: Pendahuluanunclassified

Efek Protektif Penggunaan Antiradiasi Alpha Spin Terhadap Histologi Hipokampus Tikus Putih (Rattus novergicus) Galur Sprague dawley yang Terpapar Gelombang Elektromagnetik Ponsel

Prasetia

Rudiyanto

Sari

2020

JHSP

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Exposure to cellphone electromagnetic radiation can cause oxidative stress which can later lead to changes in the hippocampal pyramidal cells. This change can be characterized by a reduction in the number of pyramidal cells and a change in cell morphology characterized by occurrence of picnosis or hydropic degeneration in the hippocampal pyramidal cell nucleus. Alpha Spin can inhibit cell phone electromagnetic radiation exposure through the quantum energy field formed by Alpha Spin. This study aims to determine the protective effect of the use of Alpha spin antiradiation on the histology of the hippocampus of white rats (Rattus norvegicus) Sprague dawley strains exposed to mobile electromagnetic waves. Laboratory experimental research using randomized controlled methods with a post test only control group design. Samples were 30 white rats divided into 3 groups. The control group (K) was only given food and drink, the treatment group 1 (P1) was exposed to cellphone electromagnetic waves and the treatment group 2 (P2) was exposed to cellphone electromagnetic waves and placed Alpha Spin. Exposure is done 2 hours / day for 30 days. There were mean differences in all groups with a significant value, which was p <0.05. There is a protective effect of Alpha Spin antiradiation on the histology of the hippocampus white rat (Rattus norvegicus) Sprague dawley strain that is exposed to cellphone electromagnetic waves.

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“…[ 3 ] Cell phones are considered as an important invention that has changed communication ways in this modern world. [ 4 ] However, using cell phones has had irregular growing rate in recent years. [ 5 ] This rapid increase of using cell phones has provided worries about radiated radiofrequency waves from them.…”

Section: Introductionmentioning

confidence: 99%

Mobile phone distance from head and temperature changes of radio frequency waves on brain tissue

2018

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Background:Analyzing the possible negative effects of using cell phones on the users’ health is an important and vital affair due to rapid growth and extensive use of these devices on human communications and interactions. The aim of this study was to determine the effect of increasing the distance of cell phones to brain tissue on the temperature of the central and gray matters of brain due to the heat generated by radio frequency waves.Methods:This study was an experimental study. A cow's brain tissue was analyzed in a compartment with three thicknesses of 2, 12, and 22 mm, in the distances of 4 mm and 4 cm from a cell phone for 15 min. Lutron thermometer was used to measure the tissue temperature, and the data analysis were done by Lutron and MATLAB software packages.Results:The tissue temperature was increased while confronting with a cell phone in distances of 4 mm and 4 cm in all the three thicknesses of 2, 12, and 22 mm. The tissue temperature was higher after removing the confrontation at 4 mm distance as compared to the distance of 4 cm.Conclusions:During confrontation and after that with the cell phone, reducing the distance of brain tissue and the cell phone increased the tissue temperature intensely. In fact, by increasing the cell phone distance from brain tissue, the thermal effect of radiofrequency waves was reduced.

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Biochemical and histological studies on adverse effects of mobile phone radiation on rat’s brain

Cited by 34 publications

References 30 publications

The Antioxidant Content and Protective Effect of Argan Oil and Syzygium aromaticum Essential Oil in Hydrogen Peroxide-Induced Biochemical and Histological Changes

The Antioxidant Content and Protective Effect of Argan Oil and Syzygium aromaticum Essential Oil in Hydrogen Peroxide-Induced Biochemical and Histological Changes

Efek Protektif Penggunaan Antiradiasi Alpha Spin Terhadap Histologi Hipokampus Tikus Putih (Rattus novergicus) Galur Sprague dawley yang Terpapar Gelombang Elektromagnetik Ponsel

Mobile phone distance from head and temperature changes of radio frequency waves on brain tissue

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