Bioactive Glass Coatings Synthesized by Pulsed Laser Deposition Technique

Abstract

Surface modification of medical implants is often required to improve their biocompatibility or, through bioactive properties of the surface material, facilitate its intergrowth with the living tissue. Bioactive-glass coatings can serve that purpose for the bone implants. We report a successful preparation of silicate-phosphate bioactive-glass coating on titanium substrate using the pulsed laser deposition method and present the coating characterization in terms of bonding configuration and chemical activity. The former was studied with high-resolution Raman microspectroscopy and revealed the presence of structural units responsible for the material's bioactivity. The bioactivity was also tested directly, in vitro, by soaking the samples in the simulated body fluid and examining the result with the Raman spectroscopy. The Raman spectrum, typical of hydroxyapatite was observed proving that the bone-like-material formed on the coating's surface.

Analysis of solvent induced porous PMMA–Bioglass monoliths by the phase separation method – mechanical and in vitro biocompatible studies

“…The feature near 814 cm À1 is attributed to the CC 4 symmetric stretching of the PMMA molecules. 38 38,39 This spectral evidence confirms the formation of the PMMA-Bioglass composites. The spectral intensity of phosphate and Q 4 is slightly higher in the ethanol-water prepared scaffold as indicated by the vertical lines.…”

“…) and Q 4 (Si-O-Si = 1601) components respectively. 39 In general, the high abundance of the Q 2 component represents a higher bioactivity in the bioactive glasses. Furthermore, the peaks present at 954 and 974 cm À1 are due to the P-O symmetric vibrations (PO 4 3À ) and P-O-P stretching vibrations of the phosphate molecules present in the glass network.…”

Structural variations of bioactive glasses obtained by different synthesis routes

“…The band in this spectral region is also characteristic for the asymmetric stretching of Q 4 Si units [45,46]. The broadening of the 1073 cm −1 band suggests the presence of these entities in the structure of A2_gel glass.…”

“…Raman spectrum shows the band at 1034-1051 cm −1 , which corresponds to asymmetric stretching of bridging oxygen in Q 1 , Q 2 , Q 3 and Q 4 Si units [44,46]. Furthermore, two bands at 958-972 cm −1 and 1000-1019 cm −1 indicate the presence of Q 0 and Q 1 P entities, respectively [28,44,47].…”

Thermal treatment stimulus on erythrocyte compatibility and hemostatic behavior of one‐dimensional bioactive nanostructures

“…Likewise, Si‐O‐Si bending vibration was observed in the range of 833 cm −1 (Aguiar, Serra, Gonzalez, & Leon, 2009). The band at 938 cm −1 in 800‐3h structure is dominated with Q 2 metasilicate chains (Si 2 O 6 4− ), Kwiatkowska, Suchanek, and Rajchel (2012) reported that abundance of Q 2 vibrations in bioactive materials has the characteristic nature of high bioactivity. In all the bioactive materials, around 960 to 970 cm −1 peaks designate the P‐O symmetric vibrational modes (Notingher et al, 2003).…”