Structural variations of bioactive glasses obtained by different synthesis routes

Dziadek, Michał; Zagrajczuk, Barbara; Jeleń, Piotr; Olejniczak, Zbigniew; Cholewa‐Kowalska, Katarzyna

doi:10.1016/j.ceramint.2016.06.095

Cited by 76 publications

(68 citation statements)

References 75 publications

(154 reference statements)

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“…ACP-OCP-CDHA maturation process was reported as similar to in vivo bone biomineralization [42,44]. In case of bioactive glasses, bioactivity process depends mainly on their chemical composition, as well as textural (porosity, specific surface area) and structural characteristics [21,22,50]. Nevertheless, when considering bioactive response of composite materials, in which bioactive glass particles are dispersed in polymer matrix, other parameters such as BG particle distribution in matrix, composite porosity, specific surface area, surface topography and wettability must also be taken into account.…”

Section: Discussionmentioning

confidence: 99%

“…Such composites combine excellent biocompatibility, relatively high mechanical strength, ease of processing, as well as low degradation rate of PCL [9,[18][19][20] with excellent bone-bonding ability, osteoconductive and/or osteoinductive character, stiffness and high hydrophilicity of bioactive glasses [8,9,18,21,22]. Furthermore, there is a possibility to use sol-gel-derived glass particles that have a larger surface area and -OH groups present in their structure, and therefore usually exhibit higher bioactivity than conventional melt-derived glasses [23,24].…”

Section: Introductionmentioning

confidence: 99%

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Poly(ε-caprolactone)-based membranes with tunable physicochemical, bioactive and osteoinductive properties

Dziadek¹,

Zagrajczuk²,

Menaszek

et al. 2017

J Mater Sci

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In contrast to currently used materials, membranes for the treatment of bone defects should actively promote regeneration of bone tissue beyond their physical barrier function. What is more, both material properties and biological features of membranes should be easily adaptable to meet the needs of particular therapeutic applications. Therefore, the role of preparation methods (nonsolvent-induced phase separation and thermal-induced phase separation) of poly(ε-caprolactone)-based membranes and their modification with gel-derived bioactive glass (BG) particles of two different sizes (\45 and \3 μm) in modulating material morphology, polymer matrix crystallinity, surface wettability, kinetics of in vitro bioactivity and also osteoblast response was investigated. Both surfaces of membranes were characterised in terms of their properties. Our results indicated a possibility to modulate microstructure (pore size ranging from submicron to hundreds of micrometres), wettability (from hydrophobic to fully wettable surface) and polymer crystallinity (from 19 to 60%) in a wide range by the use of various preparation methods and different BG particle sizes. Obtained composite membranes showed excellent in vitro hydroxyapatite forming ability after incubation in simulated body fluid. Here we demonstrated that bioactive layer formation on the surface of membranes occurred through ACP-OCP-CDHA-HCA transformation, that mimic in vivo bone biomineralization process. Composite membranes supported human osteoblast proliferation, stimulated cell differentiation and matrix mineralization. We proved that kinetics of bioactivity process and also osteoinductive properties of membranes can be easily modulated with the use of proposed variables. This brings new

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Poly(ε-caprolactone)-based membranes with tunable physicochemical, bioactive and osteoinductive properties

Dziadek¹,

Zagrajczuk²,

Menaszek

et al. 2017

J Mater Sci

Self Cite

View full text Add to dashboard Cite

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“…The broad bands indicate the presence of amorphous phases (Figure 3). 41 ), P-O-P stretching, asymmetric stretching of bridging oxygen in all Q species, respectively, according to the literature. The best adjustment allows the identification of the vibrations characteristic of the different structural groups present in accordance with published data.…”

Section: Resultsmentioning

confidence: 99%

“…A more detailed analysis, performed by deconvoluting the Raman spectroscopy bands (Figure 4), revealed additional information. 41 Figure 5 shows the sum of the areas of the bands associated with nonbridging oxygen vibrations. 41 ), P-O-P stretching, asymmetric stretching of bridging oxygen in all Q species, respectively, according to the literature.…”

Section: Resultsmentioning

confidence: 99%

Nontoxic glasses: Preparation, structural, electrical and biological properties

Gavinho

Prezas

Ramos

et al. 2019

Int J Applied Ceramic Tech

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Bacterial infections affect about 1 in 5 patients who receive a dental implant within 5 years of surgery. To avoid the implant rejection it is necessary for the development of innovative biomaterials, with addition or substitution of the ions, for implant coatings that promote a strong bond with the new host bone and antibacterial action. The objective of this work was to synthesize a bioactive glass with different silver concentrations to evaluate their antibacterial performance. The glasses were synthesized with up to 2% silver content by melt‐quenching. Structural, morphological, biological, and electrical properties of all samples were studied. The biological behavior was evaluated through cytotoxicity tests and antibacterial activity. The structural analysis shows that the introduction of silver do not promote significant changes, not altering the advantageous properties of the bioglass of the bioglass. It was verified that the glasses with a silver content from 0.5% to 2%, completely prevented the growth of both Staphylococcus aureus and Escherichia coli while being nontoxic toward mammalian cells. Therefore, these bioglasses are promising materials to be used in the production of dental implants with antimicrobial activity.

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“…The gel powders calcined at 610°C are mainly amorphous, but small diffraction peaks of Ca 3 SiO 5 (ICDD # 16‐0406) are present in the XRD θ‐2θ patterns (Figure A). Crystallized calcium (sodium) silicate phases were reported in the calcined Si‐Ca‐(Na)‐P glasses . Weak silver peaks are detected for the powder containing silver (10Ag).…”

Section: Resultsmentioning

confidence: 99%

Sol‐gel preparation and properties of Ag‐containing bioactive glass films on titanium

Alajmi

Shen

et al. 2017

Int J Applied Ceramic Tech

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Ag‐containing bioactive glass films (Ag/Ca atomic ratios of 0, 5% and 10%) were sol‐gel prepared for bioactive and antibacterial modification of titanium. The gel powders calcined at 610°C are mainly amorphous confirmed by x‐ray diffraction, but small diffraction peaks of Ca3SiO5 and silver are detected. The film surface is porous with the pore size of ~200 nm. Silver‐rich sub‐micro particles with sizes of 100‐480 nm are present at the surface of Ag‐glass films. CaP phase, metallic silver and silica are detected by x‐ray photoelectron spectroscopy. The mean apparent bonding strength of the films is as high as 21±1 MPa measured by the pull‐off test. The potentiodynamic polarization test shows that the coated samples have better corrosion resistance than the polished sample. The Ag‐glass coatings and their wafer samples exhibit antibacterial activity against S. aureus. The coated samples are covered by apatite layer after soaked in the simulated body fluid for 2 weeks, demonstrating their bioactivity.

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Structural variations of bioactive glasses obtained by different synthesis routes

Cited by 76 publications

References 75 publications

Poly(ε-caprolactone)-based membranes with tunable physicochemical, bioactive and osteoinductive properties

Poly(ε-caprolactone)-based membranes with tunable physicochemical, bioactive and osteoinductive properties

Nontoxic glasses: Preparation, structural, electrical and biological properties

Sol‐gel preparation and properties of Ag‐containing bioactive glass films on titanium

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